FACTOID # 153: In all the countries surveyed, women do more housework than men.
 
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CD8 (cluster of differentiation 8) is a molecule that is expressed on the surface of cytotoxic T cells. It is attracted to portions of the Class I MHC molecule. This affinity keeps the cytotoxic T cell and the target cell bound closely together during antigen-specific activation. Cytotoxic T cells with CD8 surface protein are called CD8+ T cells. Cluster of differentiation (CD) molecules are markers on the cell surface, as recognized by specific sets of antibodies, used to identify the cell type, stage of differentiation and activity of a cell. ... A cytotoxic (or TC) T cell is a T cell (a type of white blood cell) which has on its surface antigen receptors that can bind to fragments of antigens displayed by the Class I MHC molecules of virus infected somatic cells and tumor cells. ... MHC class I molecules are cell surface proteins found on most cells of the body. ...


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CD8 - Wikipedia, the free encyclopedia (114 words)
CD8 (cluster of differentiation 8) is a glycoprotein which serves as a co-receptor that is expressed on the surface of cytotoxic T cells.
CD8 consists of an α and a ß chain, which both resemble an immunoglobulin-like domain that is connected to the membrane by a thin stalk.
This affinity keeps the T cell receptor of the cytotoxic T cell and the target cell bound closely together during antigen-specific activation.
Product Detail for CD8 (IM2638) (320 words)
The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8α homodimer or as a CD8αβ heterodimer.
CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells.
CD8 is widely used as a marker of cytotoxic T lymphocytes.
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