CSAIL's research activities are organized around a number of semi-autonomous research groups, each of which is headed by one or more professors or research scientists. These groups are divided up into seven general areas of research:
David D. Clark, former chief protocol architect for the Internet, and co-author with Jerome H. Saltzer (also a CSAIL member) and David P. Reed of the influential paper "End-to-End Arguments in Systems Design" (see End-to-end principle)
CSAIL is the result of a merger in July 2003 of the Artificial Intelligence Laboratory and the Laboratory for Computer Science.
In a real sense, the CSAIL conference and reception will showcase a merger in progress, as the integration of LCS and AI Lab will not be fully complete until the physical move.
CSAIL is also working on molecular biology projects with the Whitehead Institute's Rick Young, looking at developing algorithms to identify gene regulatory pathways in cells.