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CSF analysis reached a peak in the 1950s and early 1960s, when almost no workup of a significant central nervous system (CNS) problem was performed without a lumbar puncture (LP).
CSF analysis remains important in the diagnosis of infections (eg, bacterial, mycobacterial, fungal, viral, protozoan) and certain inflammatory diseases (eg, multiple sclerosis, Guillain-Barre syndrome, vasculitis).
CSF pressure should be measured with the subject in the horizontal lateral decubitus position (as described previously) and relaxed as much as possible.
Cerebrospinal fluid (CSF) leaks are composed of CSF rhinorrhea or otorrhea, which implies an abnormal communication between the subarachnoid space and the nasal cavity or tympanomastoid space.
CSF rhinorrhea involves a breakdown of all barriers that separate the subarachnoid space from the nasal cavity or paranasal sinuses.
Temporal bone CSF leak is an indication of an abnormal communication or series of communications between the subarachnoid space and the temporal bone.
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