Canarreos Archipelago is an archipelago south of Cuba. It is located in the Caribbean Sea, at 21.6394444° N 82.2361111° W. Largest island of the archipelago is Isla de la Juventud, the second largest is Cayo Largo del Sur. Map of Central America and the Caribbean A Caribbean beach in Isla Margarita, Venezuela. ... The Isla de la Juventud (Spanish) or Isle of Youth (English) is the largest island of Cuba after Cuba proper. ... Shallow water surrounds Cayo Largo, evidenced by the lighter shade of blue around the islands perimeter. ...