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Dioscorins from different Dioscorea species all exhibit both carbonic anhydrase and trypsin inhibitor activities (2997 words) |
 | Carbonic anhydrase activity staining (A) and trypsin inhibitor activity staining (B) of yam tuber crude extracts. |
| Inhibition experiments of carbonic anhydrase activity of dioscorins from Dioscorea batatas Decne without inhibitors (A, control) or with 5 mM acetazolamide (requiring protection against light) (B); or with 5 mM pyridinedicarboxyl acid (C) in 100 mM Tris buffer (pH 8.5) with gentle shaking for 2 h followed by carbonic anhydrase activity staining. |
| The activity of sulfonamides and anions against the carbonic anhydrases of animals, plants, and bacteria. |
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Patent 5944021: Therapeutic use of a carbonic anhydrase enzyme inhibitor for the treatment of brain edema (1878 words) |
| It is preferred to combine the a carbonic anhydrase enzyme inhibitor therapy with hyperventilation of the lungs, even including the use of supplemental oxygen, thereby to reduce the concentration of carbon dioxide in the blood and hence in the brain. |
| The method of claim 1 wherein a first dose of said carbonic anhydrase enzyme inhibitor is administered by intravenously injecting a mixture comprising said carbonic anhydrase enzyme inhibitor and sterile water and administering a subsequent dose of said carbonic anhydrase enzyme inhibitor by ingestion. |
| The method of claim 11 wherein a first dose of said carbonic anhydrase enzyme inhibitor is administered by intravenously injecting a mixture comprising said carbonic anhydrase enzyme inhibitor and sterile water and administering a subsequent dose of said carbonic anhydrase enzyme inhibitor by ingestion. |
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