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Encyclopedia > Carcinoid
Carcinoid
Classifications and external resources
ICD-10 E34.0
ICD-9 259.2
ICD-O: M8240/3
OMIM 114900
DiseasesDB 2040
MedlinePlus 000347
eMedicine med/271 
Picture of a carcinoid tumour that encroaches into lumen of the small bowel. Pathology specimen. The prominent folds are plicae circulares, a characteristic of small bowel.
Picture of a carcinoid tumour that encroaches into lumen of the small bowel. Pathology specimen. The prominent folds are plicae circulares, a characteristic of small bowel.

Carcinoid, also carcinoid tumour and carcinoid tumor, is a slow-growing but often malignant type of neuroendocrine tumour, originating in the cells of the neuroendocrine system. The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ... // E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other... The International Statistical Classification of Diseases and Related Health Problems (commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ... The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ... The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ... The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The Diseases Database is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ... MedlinePlus (medlineplus. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Image File history File links Multiple_Carcinoid_Tumors_of_the_Small_Bowel_2. ... Image File history File links Multiple_Carcinoid_Tumors_of_the_Small_Bowel_2. ... Diagram showing the small intestine In biology the small intestine is the part of the gastrointestinal tract between the stomach and the large intestine (colon). ... The circular folds (valves of Kerkring) are large valvular flaps projecting into the lumen of the bowel. ... In medicine, malignant is a clinical term that is used to describe a clinical course that progresses rapidly to death. ... Neuroendocrine tumors, or more properly gastro-entero-pancreatic or gastroenteropancreatic neuroendocrine tumors (GEP-NETs), are cancers of the interface between the endocrine (hormonal) system and the nervous system. ... Neuroendocrinology is the study of the interactions between the nervous system and the endocrine system. ...

Contents

Symptoms

Most carcinoids are asymptomatic through the natural lifetime and are discovered only upon surgery for unrelated reasons; these are called coincidental carcinoids. But all carcinoids are considered to have malignant potential.


About ten percent of carcinoids secrete excessive serotonin (5-HT), causing: Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract. ...

  • Flushing
  • Diarrhea
  • Wheezing
  • Abdominal Cramping
  • Peripheral Edema

This set of symptoms is called carcinoid syndrome or (if acute) carcinoid crisis. Occasionally, haemorrhage or the effects of tumor bulk are the presenting symptoms. The most common originating sites of carcinoid are the appendix (60%) and the ileum; ovarian origin is rare. Hemorrhage (alternate spelling is Haemorrhage) is the medical term meaning bleeding. ...


Treatment

Surgery, if feasible, is the only curative therapy. If the tumour has metastasized, (most commonly, to the liver), the tumour may be ineligible for surgery (unresectable). A cardiothoracic surgeon performs a mitral valve replacement at the Fitzsimons Army Medical Center. ...


Chemotherapy is of little benefit and is generally not indicated. Octreotide (a somatostatin analogue) may decrease the secretory activity of the carcinoid. Chemotherapy is the use of chemical substances to treat disease. ... Somatostatin is a hormone. ... Somatostatin is a hormone. ...


Carcinoid tumours occur most commonly in the appendix, followed by the small intestine, rectum and stomach. They have a very slow growth rate compared to most malignant tumours.


See also

Carcinoid syndrome refers to the array of symptoms that occur secondary to carcinoid tumors. ...

External links


  Results from FactBites:
 
Dr. Koop - Carcinoid Syndrome- Health Encyclopedia and Reference (517 words)
Carcinoid syndrome is caused by an uncommon intestinal or lung tumor, called a carcinoid tumor, that secretes excess quantities of hormones.
Symptoms associated with carcinoid tumors (also called argentaffinomas) include attacks of severe flushing of the skin lasting from minutes to days, watery diarrhea, abdominal cramps, bronchoconstrictive attacks, and edema (swelling) of the head and neck.
Metastatic carcinoid tumors may be diagnosed by the clinical findings and by elevated levels of 24-hour urinary 5-hydroxyindolacetic acid (5-HIAA), a metabolic product of the serotonin produced by the tumor.
National Cancer Institute - Gastrointestinal Carcinoid Tumor Treatment (841 words)
A gastrointestinal carcinoid tumor is cancer that forms in the lining of the gastrointestinal tract.
Carcinoid tumors that start in the rectum (the last several inches of the large intestine) usually do not produce hormones.
The hormones produced by gastrointestinal carcinoid tumors are usually destroyed by blood and liver enzymes.
  More results at FactBites »


 

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