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Encyclopedia > Carolyn R. Bertozzi

Dr. Carolyn Ruth Bertozzi is an award-winning chemist. She holds positions as Professor of Chemistry and Molecular and Cell Biology at the University of California, Berkeley; Professor of Molecular and Cellular Pharmacology at the University of California, San Francisco; is an Investigator of the Howard Hughes Medical Institute; and Director of the Molecular Foundry, a nanoscience research center at Lawrence Berkeley National Laboratory. She was one of the youngest scientists ever to receive a MacArthur "genius" award, at only 33 years. Chemistry (from Persian language کیمیا Kimia and Greek χημεία khemeia[1] meaning alchemy) is the science of matter at the atomic to molecular scale, dealing primarily with collections of atoms, such as gases, molecules, crystals, and metals. ... The University of California (UC) is a public university system in the state of California. ... The Foundry is located in Berkeley. ... A mite next to a gear chain produced using nanotechnology Nanotechnology as a collective term refers to technological developments on the nanometer scale, usually 0. ... The Berkeley Lab is perched on a hill overlooking the Berkeley central campus and San Francisco Bay. ... The John D. and Catherine T. MacArthur Foundation is a private, independent grantmaking institution. ...

Contents

Biography

Bertozzi was born in Boston, Massachusetts, in 1966. She received her bachelor's in chemistry at Harvard University, where she worked with Joe Grabowski on the design and construction of a photoacoustic calorimeter. After graduating she worked briefly at Bell Labs with Chris Chidsey and at Massachusetts General Hospital. Chemistry (from Persian language کیمیا Kimia and Greek χημεία khemeia[1] meaning alchemy) is the science of matter at the atomic to molecular scale, dealing primarily with collections of atoms, such as gases, molecules, crystals, and metals. ... Harvard redirects here. ... Bell Laboratories (also known as Bell Labs and formerly known as AT&T Bell Laboratories and Bell Telephone Laboratories) was the main research and development arm of the United States Bell System. ...


Bertozzi completed her Ph.D. at Berkeley in 1993 with Mark Bednarski, working on the chemical synthesis of oligosaccharide analogs. She was a postdoctoral fellow at UCSF with Steven Rosen, where she studied the activity of endothelial oligosaccharides in promoting cell adhesion at inflammation sites. Bertozzi joined the UC Berkeley faculty in 1996.


Bertozzi studies the glycobiology underlying diseases such as cancer, inflammatory disorders such as arthritis, and infectious diseases such as tuberculosis. In particular, Bertozzi has significantly advanced understanding of cell surface oligosaccharides involved in cell recognition and inter-cellular communication. The term “oligosaccharide” refers to a short chain of sugar molecules (“oligo” means “few” and “saccharide” means “sugar. ...


The Bertozzi lab has also developed significant tools for research, including chemical tools for studying glycans in living systems and more recently nanotechnologies for probing biological systems. Glycans are polysaccharides. ...


Bertozzi's father, William Bertozzi [1], and sister, Andrea Bertozzi [2], are also scientists.


Significant Papers and Publications

  • Science 1997
  • Science 2000
  • Prescher / Bertozzi Nature , the Staudinger ligation paper
  • Glycochemistry (2001) edited by Peng George Wang and Bertozzi

Awards and Honors

President Harding and the National Academy of Sciences at the White House, Washington, DC, April 1921 The National Academy of Sciences (NAS) is a corporation in the United States whose members serve pro bono as advisers to the nation on science, engineering, and medicine. ... Iota Sigma Pi is an elective US honor society for women in chemistry, first established in 1902. ... The John D. and Catherine T. MacArthur Foundation is a private, independent grantmaking institution. ... The American Chemical Society (ACS) is a learned society (professional association) based in the United States that supports scientific inquiry in the field of chemistry. ... The House of the Academy, Cambridge, Massachusetts. ... The American Association for the Advancement of Science (AAAS) is an organization that promotes cooperation between scientists, defends scientific freedom, encourages scientific responsibility and supports scientific education for the betterment of all humanity. ...

Notes and References

    External Links

    • Bertozzi Lab


     

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