 | | Cefalotin | | Systematic (IUPAC) name | (6R,7R)-3-(acetoxymethyl)- 8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia- 1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid | | Identifiers | | CAS number | 153-61-7 | | ATC code | J01DB03 | | PubChem | 6024 | | DrugBank | APRD00859 | | Chemical data | | Formula | C16H16N2O6S2 | | Mol. weight | 396.44 g/mol | | Pharmacokinetic data | | Bioavailability | n/a | | Metabolism | hepatic | | Half life | 0.5–1 hour | | Excretion | renal | | Therapeutic considerations | | Pregnancy cat. | A (Aus) IUPAC nomenclature is a systematic way of naming organic chemical compounds. ...
CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ...
The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
PubChem is a database of chemical molecules . ...
DrugBank is a database available at the University of Alberta that provides information about thousands of products. ...
A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ...
The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
Metabolism (from Greek μεÏαβολιÏμÏÏ metabolismos) is the biochemical modification of chemical compounds in living organisms and cells. ...
The liver is an organ in vertebrates including humans. ...
The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ...
Excretion is the biological process by which an organism chemically separates waste products from its body. ...
Kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
Motto: None. ...
| | Legal status | Schedule 4 (Aus) POM (UK) The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...
Motto: None. ...
| | Routes | IV | Cefalotin (INN) (IPA: [kɛfəˈlotən, sɛfə-]) or cephalothin (USAN) (IPA: [kɛfəˈloθən, sɛfə-]) is a first-generation cephalosporin antibiotic. It was the first cephalosporin marketed and continues to be widely used. It is an intravenously-administered agent with a similar antimicrobial spectrum to cefazolin and the oral agent cefalexin. Cefalotin sodium is commonly marketed under the trade name Keflin (Lilly). In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
An intravenous drip in a hospital Intravenous therapy or IV therapy is the administration of liquid substances directly into a vein. ...
An International Nonproprietary Name (INN) is the official non-proprietary or generic name given to a pharmaceutical substance, as designated by the World Health Organization. ...
The International Phonetic Alphabet (IPA) is a system of phonetic notation devised by linguists to accurately and uniquely represent each of the wide variety of sounds (phones or phonemes) used in spoken human language. ...
United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States. ...
The International Phonetic Alphabet (IPA) is a system of phonetic notation devised by linguists to accurately and uniquely represent each of the wide variety of sounds (phones or phonemes) used in spoken human language. ...
The cephalosporins, are a class of β-lactam antibiotics. ...
An antibiotic is a drug that kills or slows the growth of bacteria. ...
An intravenous drip in a hospital Intravenous therapy or IV therapy is the administration of liquid substances directly into a vein. ...
Cefazolin is an antibiotic in the chemical family of Cephalosporin. ...
Cephalexin structure (racemic) Cefalexin (previously also British Approved Name Cephalexin) is a drug that is a member of the cephalosporin class of antibiotics. ...
One of the worlds largest corporations, Eli Lilly and Company NYSE: LLY is a global pharmaceutical company. ...
Clinical use
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The cephalosporins, are a class of β-lactam antibiotics. ...
See also The cephalosporins, are a class of β-lactam antibiotics. ...
Cephalexin structure (racemic) Cefalexin (previously also British Approved Name Cephalexin) is a drug that is a member of the cephalosporin class of antibiotics. ...
| Cephalosporin Antibiotics (J01D) edit | | | First Generation: | Cefacetrile, Cefadroxil, Cefalexin, Cephaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole The cephalosporins, are a class of β-lactam antibiotics. ...
An antibiotic is a drug that kills or slows the growth of bacteria. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
Cefacetrile (also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in G+ and G- bacterial infections. ...
Cefadroxil is a broadspectrum antibiotic effective on both bactria GRAM +ve and GRAM -ve bactria. ...
Cephalexin structure (racemic) Cefalexin (previously also British Approved Name Cephalexin) is a drug that is a member of the cephalosporin class of antibiotics. ...
Cefazolin is an antibiotic in the chemical family of Cephalosporin. ...
| | Second Generation: | Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam Cefaclor (brand name Raniclor®) is a 2nd generation cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections. ...
Cefprozil, sometimes spelled cefproxil and sold under the brand name Cefzil, is a cephalosporin antibiotic. ...
Cefuroxime is an cephalosporin antibiotic that has been widely available in the USA since 1977. ...
| | Third Generation: | Cefcapene , Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef Cefdinir is a semi-synthetic antibiotic in the third generation of the cephalosporin family of antibiotics. ...
Cefixime is an oral third generation cephalosporin antibiotic. ...
Cefotaxime is a third generation intravenous cephalosporin antibiotic. ...
Cefpodoxime is an oral third generation cephalosporin antibiotic. ...
Ceftazidime is an antibiotic which eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, gynecological, and urinary tract infections. ...
Ceftriaxone (trade name Rocephin®) is a third-generation cephalosporin antibiotic. ...
| | Fourth Generation: | Cefclidine, Cefepime, Cefetecol Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome This article needs to be cleaned up to conform to a higher standard of quality. ...
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