Each generation has a broader spectrum of activity than the one before.
In addition, cefoxitin (Mefoxin), a cephamycin, is highly active against anaerobic bacteria, which makes it useful in prevention and treatment of infections of the intestines.
The third generation drugs, cefotaxime, ceftizoxime, ceftriaxone, and others, cross the blood-brain barrier and may be used to treat meningitis and encephalitis.
A strangulated hernia can be distinguished from an incarcerated hernia by the presence of fever; pain that persists after the doctor has reduced the hernia manually; and pain that is more severe than warranted by the examination findings.
If the doctor suspects that the hernia is strangulated, he or she will give the patient a broad-spectrum antibiotic (usually cefoxitin) intravenously before the patient is taken to the operating room.
Adults scheduled for a nonemergency herniorraphy are given standard blood tests and a urinalysis.
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