 | | Cefuroxime | | Systematic (IUPAC) name | | 4-(carbamoyloxymethyl)-8- [2-(2-furyl)-2-methoxyimino-acetyl]amino -7-oxo- 2-thia-6-azabicyclo[4.2.0]oct -4-ene-5-carboxylic acid IUPAC nomenclature is a systematic way of naming organic chemical compounds. ...
| | Identifiers | | CAS number | 55268-75-2 | | ATC code | J01DC02 | | PubChem | 41375 | | DrugBank | APRD00285 | | Chemical data | | Formula | C16H16N4O8S | | Mol. weight | 424.386 g/mol | | Pharmacokinetic data | | Bioavailability | 37% on empty stomach, up to 52% if taken after food | | Metabolism | axetil moiety is metabolized to acetaldehyde and acetic acid | | Half life | 80 minutes | | Excretion | ? | | Therapeutic considerations | | Pregnancy cat. | ? CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ...
The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
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DrugBank is a database available at the University of Alberta that provides information about thousands of products. ...
A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ...
The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
Metabolism (from Greek μεταβολισμός metabolismos) is the biochemical modification of chemical compounds in living organisms and cells. ...
R-phrases , , S-phrases , , , Flash point −39 °C Autoignition temperature 185 °C RTECS number AB1925000 Supplementary data page Structure and properties n, εr, etc. ...
Acetic acid, also known as ethanoic acid, is an organic chemical compound best recognized for giving vinegar its sour taste and pungent smell. ...
The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ...
Excretion is the biological process by which an organism chemically separates waste products from its body. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
| | Legal status | | | Routes | oral, intramuscular, intravenous | Cefuroxime is a second-generation cephalosporin antibiotic that has been widely available in the USA since 1977. It is also available under the brand name Ceftin. Glaxo Smith Kline sells the antibiotic in Australia (and other countries, such as Israel) under the name Zinnat, with the Australian pharmaceutical code of R 47621. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...
In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
Intramuscular injection is an injection of a substance directly into a muscle. ...
An intravenous drip in a hospital Intravenous therapy or IV therapy is the administration of liquid substances directly into a vein. ...
The cephalosporins, are a class of β-lactam antibiotics. ...
Staphylococcus aureus - Antibiotics Test plate. ...
Indications
As for the cephalosporins, although as a second-generation it is less susceptible to Beta-lactamase and so may have greater activuty against Haemophilus influenzae, Neisseria gonorrhoeae and Lyme disease. The cephalosporins, are a class of β-lactam antibiotics. ...
Beta-lactamase is a type of enzyme (EC 3. ...
Binomial name Haemophilus influenzae (Lehmann & Neumann 1896) Winslow 1917 Haemophilus influenzae, formerly called Pfeiffers bacillus or Bacillus influenzae, is a non-motile Gram-negative coccobacillus first described in 1892 by Dr. Richard Pfeiffer during an influenza pandemic. ...
Binomial name Neisseria gonorrhoeae Zopf, 1885 Neisseria gonorrhoeae is a species of Gram-negative (see also Gram Stain) bacteria responsible for the disease gonorrhoea. ...
Lyme disease or Lyme borreliosis is the most common tick-borne disease in the United States and Europe, and one of the fastest growing infectious diseases in the United States. ...
Side effects Cefuroxime is generally well tolerated and side effects are usually transient. Cefuroxime if taken with food is both better absorbed and less likely to cause its commonest upsets of diarrhea, nausea, vomiting and abdominal pain.
As with the cephalosporins generally, there is a 10% cross-over sensitivity for those people with allergy to penicillins. The cephalosporins, are a class of β-lactam antibiotics. ...
An allergy can refer to several kinds of immune reactions including Type I hypersensitivity in which a persons body is hypersensitised and develops IgE type antibodies to typical proteins. ...
Penicillin nucleus Penicillin (sometimes abbreviated PCN) refers to a group of β-lactam antibiotics used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms. ...
| Cephalosporin Antibiotics (J01D) edit | | | First Generation: | Cefacetrile, Cefadroxil, Cefalexin, Cephaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole The cephalosporins, are a class of β-lactam antibiotics. ...
Staphylococcus aureus - Antibiotics Test plate. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
Cefacetrile (also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in G+ and G- bacterial infections. ...
Cefadroxil is a broadspectrum antibiotic effective on both bactria GRAM +ve and GRAM -ve bactria. ...
Cephalexin structure (racemic) Cefalexin (previously also British Approved Name Cephalexin) is a drug that is a member of the cephalosporin class of antibiotics. ...
Cephaloglycin is a first generation cephalosporin antibiotic. ...
Cefalotin (INN) (IPA: ) or cephalothin (USAN) (IPA: ) is a first-generation cephalosporin antibiotic. ...
Cefapirin (or cephapirin) is a first-generation cephalosporin antibiotic. ...
Cefazolin is an antibiotic in the chemical family of Cephalosporin. ...
Cefradine (INN) or cephradine (former BAN) is a first generation cephalosporin antibiotic. ...
| | Second Generation: | Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam Cefaclor (brand name Raniclor®) is a 2nd generation cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections. ...
Ceforanide is a second-generation cephalosporin antibiotic Crowle A, Sbarbaro J, May M (1988). ...
Cefotiam is a second-generation cephalosporin antibiotic. ...
Cefprozil, sometimes spelled cefproxil and sold under the brand name Cefzil, is a cephalosporin antibiotic. ...
| | Third Generation: | Cefcapene , Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef Cefdinir is a semi-synthetic antibiotic in the third generation of the cephalosporin family of antibiotics. ...
Cefixime is an oral third generation cephalosporin antibiotic. ...
Cefmenoxime is a third-generation cephalosporin antibiotic. ...
Cefotaxime is a third generation intravenous cephalosporin antibiotic. ...
Cefpiramide is a third-generation cephalosporin antibiotic. ...
Cefpodoxime is an oral third generation cephalosporin antibiotic. ...
Ceftazidime is an antibiotic which eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, gynecological, and urinary tract infections. ...
Ceftriaxone (trade name Rocephin®) is a third-generation cephalosporin antibiotic. ...
| | Fourth Generation: | Cefclidine, Cefepime, Cefetecol Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome This article needs to be cleaned up to conform to a higher standard of quality. ...
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