In genetics, a centimorgan (abbreviated cM) is a unit of recombinant frequency. It is often used to imply distance along a chromosome. The centimorgan is equal to a 1% chance that a marker at one genetic locus on a chromosome will be separated from a marker at a second locus due to crossing over in a single generation. In human beings, one centimorgan is equivalent, on average, to one million base pairs. The centimorgan was named in honor of geneticist Thomas Hunt Morgan by his student Alfred Henry Sturtevant. Note that the parent unit of the centimorgan, the morgan, is never used. Genetics (from the Greek genno γεννώ= give birth) is the science of genes, heredity, and the variation of organisms. ... Figure 1: Chromosome. ... The word locus (plural loci) is Latin for place. In biology, a locus is the position of a gene (or other significant sequence) on a chromosome. ... The word locus (plural loci) is Latin for place. In biology, a locus is the position of a gene (or other significant sequence) on a chromosome. ... Chromosomal crossover is the process by which two chromosomes, paired up during Prophase I of meiosis, exchange some distal portion of their DNA. Crossover occurs when two chromosomes, normally two homologous instances of the same chromosome, break and then reconnect but to the different end piece. ... In genetics, two nucleotides on opposite complementary DNA or RNA strands that are connected via hydrogen bonds are called a base pair (often abbreviated bp). ... Thomas Hunt Morgan Thomas Hunt Morgan (September 25, 1866 - December 4, 1945) worked in natural history, zoology, and macromutation in the fruit fly Drosophila. ... Alfred Henry Sturtevant (November 21, 1891 - April 5, 1970) was an American geneticist, Sturtevant constructed the first genetic map of a chromosome in 1913. ...
A map unit (abbreviated m.u.) is synonymous with centimorgan.
In genetics, a centimorgan (abbreviated cM) is a unit of recombinant frequency.
The centimorgan is equal to a 1% chance that a marker at one genetic locus on a chromosome will be separated from a marker at a second locus due to crossing over in a single generation.
In human beings, one centimorgan is equivalent, on average, to one million base pairs.
This genetic map of the mouse shows the location of loci in terms of recombinational distance from the centromere, the correlation between the genetic and cytogenetic maps, and the known homologies to human chromosomes.
Between centimorgan distances the order of loci is the best estimate derived from consideration of the literature, particularly Copeland et al ( 1993), and again should be considered approximate.
Within a centimorgan position no attempt has been made to show the order of the loci, and loci are listed alphabetically.
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