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Encyclopedia > Central serous retinopathy
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Central serous retinopathy or CSR is a visual impairment, often temporary, usually in one eye, affecting males in the age group 20 to 50. The disorder is characerized by leakage of fluid in the central macula, which results in blurred or distorted vision (metamorphopsia). A blind or gray spot in the central vision is common, along with flashes of light. Jump to: navigation, search Listen to this article · (info) This audio file was created from the revision dated 2005-07-19, and does not reflect subsequent edits to the article. ...

Contents


Diagnosis

The diagnosis usually starts with a dilated examination of the retina, followed with confirmation by fluorescein angiography. The angiography test will usually show one or more fluorescent spots with fluid leakage. In 10%-15% of the cases these will appear in a "classic" smoke stack shape. Fluorescein angiography, or fluorescent angiography, is a technique for examining the circulation of the retina. ...


Causes

CSR is a detachment of macula layers from their supporting tissue. This allows choroidal fluid to leak into the subretinal space. The buildup of fluid seems to occur because of small breaks in the retinal pigment epithelium. Human eye cross-sectional view. ...


CSR is sometimes called idiopathic CSR which means that its cause is unknown. Nevertheless, stress appears to play an important role. Persons in stressful occupations, such as airplane pilots, have a higher incidence of CSR. The "type A personality" has also been linked to this condition. Idiopathic is a medical adjective that indicates that a recognized cause has not yet been established. ... Jump to: navigation, search Stress has different meanings in different fields: Look up stress on Wiktionary, the free dictionary. ... Type A personality is a term used to describe people who are driven, hard-working, busy, and impatient. ...


CSR has also been associated with cortisol, i.e. people who suffer from CSR have higher levels of cortisol than normal, and persons with higher levels of cortisol than normal also have a higher propensity to suffer from CSR. Cortisol is a hormone secreted by the adrenal cortex which allows the body to deal with stress, which may explain the CSR-stress association. It is also known that corticosteroids ("cortisone") --- commonly used to treat inflamations, allergies, skin conditions and even certain eye conditions --- can aggravate CSR and cause relapses. Cortisol (hydrocortisone, C21H30O5 ), is a corticosteroid hormone synthesized in the zona fasciculata of the cortex of the adrenal glands. ... A hormone (from Greek horman - to set in motion) is a chemical messenger from one cell (or group of cells) to another. ... In mammals, the adrenal glands are the triangle-shaped endocrine glands that sit atop the kidneys. ... Jump to: navigation, search Cortisone is a hormone. ...


The incidence of CSR in persons with Cushing's syndrome is 5%. Cushing's syndrome is characterized by very high cortisol levels.


Prognosis

Most patients recover normal vision without treatment in three or four months. Some visual abnormalities can remain even if visual acuity is measured at 20/20. Lasting problems can include decreased night vision and some distortion. About 50% of the patients get the severe and extensive form of the disease after 12 years of evolution. Visual acuity is the eyes ability to detect fine details and is the quantitative measure of the eyes ability to see an in-focus image at a certain distance. ... Night-vision is seeing in the dark. ...


Treatment

There is no known effective treatment for the disease. Laser photocoagulation, which effectively burns the leak area shut, is sometimes suggested. In many cases the leak is very near the central macula, where photocoagulation would leave a blind spot. Additionally, a better long term outcome has not been demonstrated with photocoagulation. So more often than not the condition goes untreated.


CSR sufferers usually find their own ways to manage the condition, which may include stress reduction and changes in nutrition (see, for example, [1]).


See Also

Diabetic retinopathy is retinopathy (damage to the retina) caused by complications of diabetes mellitus, which could eventually lead to blindness. ... Hypertension, or high blood pressure that does not respond to treatment, has several ocular manifestations. ... Listen to this article · (info) This audio file was created from the revision dated 2005-07-19, and does not reflect subsequent edits to the article. ... Cortisol (hydrocortisone, C21H30O5 ), is a corticosteroid hormone synthesized in the zona fasciculata of the cortex of the adrenal glands. ... Jump to: navigation, search Stress has different meanings in different fields: Look up stress on Wiktionary, the free dictionary. ...

External Links

  • Csreye support mailing list

  Results from FactBites:
 
Dr. Koop - Central Serous Retinopathy- Health Encyclopedia and Reference (481 words)
Retinopathy is a condition in which deterioration of the retina is caused by damage to, or over-production of, the blood vessels in the retina.
Central serous retinopathy is a slight accumulation of fluid in the macular region of the eye thatlies between the retinal pigment epithelium and the outer segments.
Central serous retinopathy is characterized by an accumulation of transparent fluid at the posterior pole of the fundus (base), causing a circumscribed area of retinal detachment at the posterior pole.
  More results at FactBites »


 
 

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