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Encyclopedia > Cephalon
Cephalon, Inc.
Type Public (NASDAQCEPH)
Founded 1987
Headquarters Frazer, Pennsylvania, United States
Key people Frank Baldino, Jr., Chairman and Chief Executive
Industry Biotechnology
Products http://www.cephalon.com/products/default.aspx
Employees 3,000
Slogan "Deliver more"
Website http://www.cephalon.com

Cephalon, Inc. (NASDAQCEPH) is a U.S. biopharmaceutical company co-founded in 1987 by Dr. Frank Baldino, Jr., a pharmacologist and former scientist with the DuPont Company, who continues to serve as its chairman and chief executive officer. The company's name relates to the Greek root word "cephalic" meaning "related to the head or brain," and it was established primarily to pursue treatments for neurodegenerative diseases. Image File history File links Question_book-3. ... This article does not cite any references or sources. ... NASDAQ in Times Square, New York City. ... Frazer is the name of two places in the United States: Frazer in Montana, Frazer Township in Pennsylvania. ... Capital Harrisburg Largest city Philadelphia Area  Ranked 33rd  - Total 46,055 sq mi (119,283 km²)  - Width 280 miles (455 km)  - Length 160 miles (255 km)  - % water 2. ... The structure of insulin Biotechnology is technology based on biology, especially when used in agriculture, food science, and medicine. ... This article is about work. ... Look up slogan in Wiktionary, the free dictionary. ... A website (alternatively, Web site or web site) is a collection of Web pages, images, videos or other digital assets that is hosted on one or several Web server(s), usually accessible via the Internet, cell phone or a LAN. A Web page is a document, typically written in HTML... NASDAQ in Times Square, New York City. ... Motto: (traditional) In God We Trust (official, 1956–present) Anthem: The Star-Spangled Banner Capital Washington, D.C. Largest city New York City Official language(s) None at the federal level; English de facto Government Federal Republic  - President George W. Bush (R)  - Vice President Dick Cheney (R) Independence - Declared - Recognized... E.I. du Pont de Nemours and Company (NYSE: DD) was founded in July 1802 as a gun powder mill by Eleuthère Irénée du Pont on Brandywine Creek, near Wilmington, Delaware. ... Neurodegenerative disease (Greek νέυρο-, néuro-, nerval and Latin dÄ“generāre, to decline or to worsen) is a condition in which cells of the brain and spinal cord are lost. ...


Cephalon is a component of the S&P MidCap 400 stock index, and is included in the Fortune 1000 list of U.S. companies based upon annual revenues for 2006.


The company's early research efforts were focused on the development of IGF-1, an insulin-like growth factor, under a collaboration with Chiron Corporation to treat amyotrophic lateral sclerosis, or Lou Gehrig's Disease, but the product has never been approved. More recently, the company has developed and commercialized products for the treatment of sleep disorders, pain, addiction and cancer. In addition to conducting research on kinase inhibitors and other small molecules, it has licensed compounds and acquired both products and other companies, including CIMA Labs, Anesta Corp. and Laboratoire Lafon. Its leading product is PROVIGIL® [citation needed] (modafinil) for the treatment of excessive daytime sleepiness associated with narcolepsy, sleep apnea and shift work sleep disorder. The company also markets ACTIQ® (oral transmucosal fentanyl citrate) and FENTORA® (fentanyl buccal tablet) for cancer pain, GABITRIL® (tiagabine HCl) for seizures, TRISENOX® (arsenic trioxide) for a rare form of leukemia, and VIVITROL® (naltrexone for extended release injectable suspension) for the treatment of alcohol addiction. In 2005, Cephalon bought Europe-based pharmaceutical company Zeneus. This added to its European presence and gave it further products for its portfolio, including ABLECET® (antifungal), TARGRETIN® (bexarotene)for cutaneous T-cell lymphoma and MYOCET® (liposomal doxorubicin) for metastatic breast cancer. The insulin-like growth factors (IGFs) are polypeptides with high sequence similarity to insulin. ... The insulin-like growth factors (IGFs) are polypeptides with high sequence similarity to insulin. ... Chiron Corporation (NASDAQ: NVS) was a multinational biotechnology firm based in Emeryville, California that was acquired by Novartis International AG on April 30, 2006. ... Amyotrophic lateral sclerosis (ALS, sometimes called Lou Gehrigs Disease, Maladie de Charcot or motor neurone disease) is a progressive, fatal, neurodegenerative disease caused by the degeneration of motor neurons, the nerve cells in the central nervous system that control voluntary muscle movement. ... A kinase inhibitor is a type of enzyme inhibitor which specifically blocks the action of protein kinase. ... For other uses, see Narcolepsy (disambiguation). ... Sleep apnea, sleep apnoea or sleep apnÅ“a is a sleep disorder characterized by pauses in breathing during sleep. ... Shift work sleep disorder affects people who frequently experience jet lag, either from travel, or by shifting their work or sleep schedules frequently. ...


The company has its corporate headquarters west of Philadelphia in Frazer, Pennsylvania and its research operations in nearby West Chester, as well as manufacturing and other operations in suburban Minneapolis, Minnesota and Salt Lake City, Utah; its European operations are based near Paris, France. Sales revenues exceeded one billion dollars in 2005, ranking Cephalon among the ten leading biopharmaceutical companies in the world. In 2006, industry publication MedAd News named the company one of the ten most respected biotechnology firms in the world. For other uses, see Philadelphia (disambiguation) and Philly. ... East Whiteland Township is a township in Chester County, Pennsylvania, United States. ... West Chester is the name of some places in the United States of America: West Chester Township, Butler County, Ohio West Chester, Ohio West Chester, Pennsylvania West Chester is also the name for a university in Pennsylvania West Chester University There are also some places named Westchester: Westchester, Los Angeles... “Minneapolis” redirects here. ... Salt Lake City is the capital and the most populous city of the U.S. state of Utah. ... This article is about the capital of France. ...


Key executives include J. Kevin Buchi, Dr. Peter Grebow, John E. Osborn, Robert P. Roche and Dr. Jeffry Vaught. Members of the board include venture capitalist William Egan, former COR Therapeutics CEO Vaughan Kailian, health-care economist Dr. Gail Wilensky, former Harvard physician and Glaxo USA head Dr. Charles Sanders and former Ambassador Kevin Moley.


External links

  • Cephalon corporate website

  Results from FactBites:
 
PharmaTimes WorldNews| Daily pharmaceutical news | Cephalon drops Sparlon after FDA says 'no' (199 words)
Cephalon has decided to drop its Sparlon drug for attention-deficit hyperactivity disorder (ADHD) after the US Food and Drug Administration rejected its application to market the drug.
Cephalon supplied new data to try to back up Sparlon's safety profile, but was unable to sway the agency.
After the FDA advisory committee rejected its application in March, Cephalon said its 2006 sales would be reduced by $100 million to $1.45-$1.5 billion as a result of the delay to the Sparlon project.
Cephalon Comments (6252 words)
Cephalon's Sparlon had been disingenuously (and perhaps to their own ultimate disservice) proclaimed as an "important new drug", instead of seeking supplemental approval on the basis of what it really is, a label extension for Provigil.
Cephalon is hardly standing pat, besides hiring a platoon of attorneys, they are about to begin clinical trials with single-isomer modafinil, which preclinically appears to have longer-duration of activity.
Cephalon is adding mass rapidly, but would still (because of the positive and growing revenue flow) be an attractive acquisition target itself for a larger company in possession of a strong CNS sales force.
  More results at FactBites »


 

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