Congophilic angiopathy is a condition in which the same amyloid protein associated with Alzheimer's disease (Amyloid beta) is deposited in the walls of the blood vessels of the brain. It is known as congophilic angiopathy because the presence of this abnormal amyloid protein can be demonstrated by microscopic examination of brain tissue after application of a special stain called Congo red. This deposition of amyloid makes these vessel walls prone to leak blood and can result in brain hemorrhages (a type of stroke). Because it is the same amyloid protein that is associated with Alzheimer's dementia such brain hemorrhages are more common in people who suffer from Alzheimer's, however they can also occur in those who have no history of dementia. The hemorrhage within the brain is usually confined to a particular lobe and this is slightly different compared to brain hemorrhages which occur as a consequence of high blood pressure (hypertension) - a more common cause of a hemorrhagic stroke (or cerebral hemorrhage). Angiopathy is a disease of the blood vessels (arteries, veins, and capillaries) that occurs when someone has diabetes for a long time. ... Amyloid beta (Aβ or Abeta) is a protein fragment of 39-42 amino acids that is the main constituent of amyloid plaques in various neurological disorders, most prominently Alzheimers disease. ... Amyloid describes various types of protein aggregations that share specific traits when examined microscopically. ... Look up Tissue on Wiktionary, the free dictionary The word tissue has several meanings: Aerial tissu is an acrobatic art form, and is one of the circus arts. ... Chemical structure of congo red Congo red is the sodium salt of benzidinediazo-bis-1-naphtylamine-4-sulfonic acid (formula: C32H22N6Na2O6S2; molecular weight: 696. ... Amyloid describes various types of protein aggregations that share specific traits when examined microscopically. ... A stroke or cerebrovascular accident (CVA) occurs when the blood supply to a part of the brain is suddenly interrupted. ... Dementia (from Latin demens) is progressive decline in cognitive function due to damage or disease in the brain beyond what might be expected from normal aging. ... For other forms of hypertension see hypertension (disambiguation) Hypertension or high blood pressure is a medical condition where the blood pressure is chronically elevated. ... A cerebral hemorrhage is bleeding directly into the brain parenchyma (tissue) itself, otherwise known as hemorrhagic stroke. ...

The condition is also known as cerebral amyloid angiopathy.