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Charles de Lorraine, duc de Mayenne, (March 26, 1554 – October 3, 1611), or Charles de Guise, was a French nobleman and military leader.
The second son of Francis of Lorraine, Duke of Guise, he was absent from France at the time of the massacre of St Bartholomew, but took part in the siege of La Rochelle in the following year, when he was created duke and peer of France.
Mayenne was urged to claim the crown for himself, but he was faithful to the official programme of the League and proclaimed Charles, cardinal of Bourbon, at that time a prisoner in the hands of Henry IV, as Charles X of France.
Charles' office of secretary of state and his care for the business of the family did not prevent him from giving time to study, and even to recreations in the form of playing the lute and violoncello, and a game of ball.
Charles was now assured that it was his duty to remain in the world; but all the more he felt he ought to visit his diocese, though the pope always opposed his departure.
Charles was at Lodi, at the funeral of the bishop.
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