Chromosome 9 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 9 spans about 136 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells. Figure 1: Chromosome. ... Binomial name Homo sapiens Linnaeus, 1758 Subspecies Homo sapiens idaltu(extinct) Homo sapiens sapiens Homo (genus). ... In molecular biology, two nucleotides on opposite complementary DNA or RNA strands that are connected via hydrogen bonds are called a base pair (often abbreviated bp). ... Space-filling model of a section of DNA molecule Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions specifying the biological development of all cellular forms of life (and most viruses). ... Cells in culture, stained for keratin (red) and DNA (green) The cell is the structural and functional unit of all living organisms, and are sometimes called the building blocks of life. ...

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 9 likely contains between 800 and 1,200 genes. This stylistic schematic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). ...

Genes

The following are some of the genes located on chromosome 9:

• ADAMTS13: ADAM metallopeptidase with thrombospondin type 1 motif, 13
• ALAD: aminolevulinate, delta-, dehydratase
• ALS4: amyotrophic lateral sclerosis 4
• ASS: argininosuccinate synthetase
• COL5A1: collagen, type V, alpha 1
• ENG: endoglin (Osler-Rendu-Weber syndrome 1)
• FXN: frataxin
• GALT: galactose-1-phosphate uridylyltransferase
• GRHPR: glyoxylate reductase/hydroxypyruvate reductase
• IKBKAP: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
• TMC1: transmembrane channel-like 1
• TSC1: tuberous sclerosis 1

ADAMTS13 (A Disintegrin And Metalloproteinase with a ThromboSpondin type 1 motif, member 13) is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. ... ASS or ass has several meanings: In zoology, an ass was the original word for donkey. ... #REDIRECT Electronic news gathering ... Galt is the name of some places in the United States of America: Galt, California Galt, Illinois Galt, Iowa Galt, Kansas Galt, Maryland Galt, Missouri Galt, Nevada The former city of Galt, Ontario, Canada, is now part of Cambridge. ...

Diseases

The following diseases are some of those related to genes on chromosome 9:

• ALAD deficiency porphyria
• amyotrophic lateral sclerosis
• amyotrophic lateral sclerosis, type 4
• citrullinemia
• Ehlers-Danlos syndrome
• Ehlers-Danlos syndrome, classical type
• familial dysautonomia
• Friedreich ataxia
• galactosemia
• hereditary hemorrhagic telangiectasia
• nonsyndromic deafness
• nonsyndromic deafness, autosomal dominant
• nonsyndromic deafness, autosomal recessive
• porphyria
• primary hyperoxaluria
• thrombotic thrombocytopenic purpura
• tuberous sclerosis

Motor Neurone Disease (MND) is a term used to cover a number of illnesses of the motor neurone. ... Citrullinemia s an inherited disorder that causes ammonia and other toxic substances to accumulate in the blood. ... Ehlers-Danlos syndrome is a group of rare (1 in 250,000 altogether) genetic disorders that diminish the bodys ability to make connective tissues. ... Familial dysautonomia, or FD, is a disorder of the autonomic nervous system resulting in variable syptoms including insensivity to pain, inability to produce tears, poor growth, and labile blood pressure. ... Friedreichs ataxia is rare, although it is one of the most common forms of autosomal recessive ataxia. ... Galactosemia is a rare genetic metabolic disorder which affects an individuals ability to properly digest the sugar galactose. ... In medicine, hereditary hemorrhagic telangiectasia (HHT), also known as Rendu-Osler-Weber syndrome, is a genetic disorder that leads to vascular malformations. ... Nonsyndromic deafness is hearing loss that is not associated with other signs and symptoms. ... This article is about the disease. ... Thrombotic thrombocytopenic purpura (TTP or Moschcowitz disease) is a rare disorder of the blood coagulation system that in most cases arises from the deficiency or inhibition of the enzyme responsible for cleaving von Willebrand factor. ... Tuberous sclerosis, (meaning hard potatoes), also known as Bourneville disease, is a rare genetic disorder primarily characterized by a triad of seizures, mental retardation, and skin lesions (called adenoma sebaceum). ...

References

• Gilbert F, Kauff N (2001). Disease genes and chromosomes: disease maps of the human genome. Chromosome 9. Genet Test 5 (2): 157-74. PMID 11551106
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