Chymosin (or rennin) is an aspartic acid protease enzyme found in rennet. It is produced by the cow of its lining of the abomasum (its fourth stomach). The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The Protein Data Bank (PDB) is a repository for 3-D structural data of proteins and nucleic acids. ... National Center for Biotechnology Information logo The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. ... Swiss-Prot is a curated biological database of protein sequences created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute. ... The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. ... Short and long arms Chromosome. ... Chromosome 3 is one of the 23 pairs of chromosomes in humans. ... The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... Look up Hugo in Wiktionary, the free dictionary. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. ... Short and long arms Chromosome. ... Chromosome 1 is, by convention, the designation for the largest human chromosome. ... Aspartic acid Aspartic acid proteases are protease enzymes which have an aspartic acid residue in the active site of the enzyme. ... Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... Rennet (IPA pronunciation: ) is a natural complex of enzymes produced in any mammalian stomach to digest the mothers milk. ... The abomasum is the fourth and final stomach compartment of the stomach in ruminants. ...

Bovine chymosin is produced nowadays recombinantly in E.coli, Aspergillus niger var awamori and K.lactis as alternative resource to the one from the cows. Binomial name Escherichia coli T. Escherich, 1885 E. coli at 10,000x magnification Escherichia coli (usually abbreviated to E. coli) is one of the main species of bacteria that live in the lower intestines of warm-blooded animals (including birds and mammals) and are necessary for the proper digestion of... ... Kluyveromyces lactis is a Kluyveromyces yeast commonly used for genetic studies and industrial applications. ...

The gene is found in humans (on chromosome 1), but it is not in a functioning form. Chromosome 1 is, by convention, the designation for the largest human chromosome. ...

Enzymatic reaction

It causes cleavage of a specific linkage, the peptide bond between phenylalanine and methionine. If this reaction applies to milk, the specific linkage between the hydrophobic (para-casein) and hydrophilic (acidic glycopeptide) group of casein inside milk would be broken, since they are joined by phenylalanine and methionine. The hydrophobic group would unite together and would form a 3D network to trap the aqueous phase of the milk. The resultant product is calcium phosphocaseinate. Look up cleavage in Wiktionary, the free dictionary. ... A peptide bond is a chemical bond that is formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule, releasing a molecule of water (H2O). ... Phenyl alanine is an α-amino acid with the formula HO2CCH(NH2)CH2C6H5. ... Methionine is an α-amino acid with the chemical formula HO2CCH(NH2)CH2CH2SCH3. ... In chemistry, hydrophobic or lipophilic species, or hydrophobes, tend to be electrically neutral and nonpolar, and thus prefer other neutral and nonpolar solvents or molecular environments. ... The adjective hydrophilic describes something that likes water (from Greek hydros = water; philos = friend). ... This page may meet Wikipedias criteria for speedy deletion. ... Casein (from Latin caseus cheese) is the most predominant phosphoprotein found in milk and cheese. ... The space we live in is three-dimensional space. ...

Due to this reaction, rennin is used to bring about the extensive precipitation and curd formation in cheese making. Curd is a dairy product obtained by curdling (coagulating) milk with rennet or an edible acidic substance such as lemon juice or vinegar and then draining off the liquid portion (called whey). ... Cheese is a solid food made from the milk of cows, goats, sheep, and other mammals. ...

External links

• MeSH Chymosin
• Chymosin at eMedicine Dictionary

Rennin clots milk and works best in acidic conditions :) Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... eMedicine is an online clinical medical knowledge base that was founded in 1996. ... Proteases (proteinases, peptidases, or proteolytic enzymes) are enzymes that break peptide bonds between amino acids of proteins. ... Aspartic acid Aspartic acid proteases are protease enzymes which have an aspartic acid residue in the active site of the enzyme. ... The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. ... Pepsin is a digestive protease (EC 3. ... Not to be confused with rennin, the active enzyme in rennet. ... Please wikify (format) this article or section as suggested in the Guide to layout and the Manual of Style. ... β-secretase — also called BACE1 (β-site of APP cleaving enzyme) or memapsin-2 — is an aspartic-acid protease important in the pathogenesis of Alzheimers disease. ... Plasmepsins are a class of at least 10 enzymes produced by the plasmodium parasite. ... HIV-1 protease is an aspartyl protease that is essential for the life-cycle of HIV. Inhibition of this protease prevents maturation of HIV particles. ...