NationMaster - Encyclopedia: Cidofovir

Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA synthesis. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Antiviral drugs are a class of medication used specifically for treating viral infections. ... Species see text Cytomegalovirus (CMV), is a genus of Herpes viruses; in humans the species is known as Human herpesvirus 5 (HHV-5). ... The retinitis is defined as the inflammation of the retina. ... Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS or Aids) is a collection of symptoms and infections in humans resulting from the specific damage to the immune system caused by the human immunodeficiency virus (HIV). ...

Cidofovir demonstrated a statistically significant effect in delaying the progression of CMV retinitis lesions in newly diagnosed patients, as well as in previously treated patients who had failed other therapies. Maintenance therapy with cidofovir involves an infusion only once every two weeks, making it a convenient treatment option. Because dosing is relatively infrequent, a permanent catheter is not necessary for infusions.

Cidofovir was developed by Gilead Sciences and is marketed with the brand name Vistide® by Gilead in the USA, and by Pfizer elsewhere. Progressive multifocal leukoencephalopathy (PML), also known as progressive multifocal leukoencephalitis, is a rare and usually fatal viral disease that is characterized by progressive damage (-pathy) or inflammation (-itis) of the white matter (leuko-) of the brain (-encephalo-) at multiple locations (multifocal). ... 2005 is a common year starting on Saturday of the Gregorian calendar. ... Smallpox (also known by the Latin names Variola or Variola vera) was a highly contagious viral disease unique to humans. ... Bioterror is the use of biological agents for terrorism. ... Gilead Sciences NASDAQ: GILD is a biopharmaceutical company that discovers, develops and commercializes therapeutics to advance the care of patients suffering from life-threatening diseases, principally HIV, hepatitis B and influenza. ... Pfizer, Incorporated (NYSE: PFE) (pronounced faÉªzÉ™É¹ or faÉªzÉ™), is the worlds largest pharmaceutical company. ...

Category: Pharmacology stubs Wikipedia does not yet have an article with this exact name. ... A section of the Anatomical Therapeutic Chemical Classification System. ... A section of the Anatomical Therapeutic Chemical Classification System. ... A section of the Anatomical Therapeutic Chemical Classification System. ... Genera Subfamily Alphaherpesvirinae Simplexvirus Varicellovirus Mardivirus Iltovirus Subfamily Betaherpesvirinae Cytomegalovirus Muromegalovirus Roseolovirus Subfamily Gammaherpesvirinae Lymphocryptovirus Rhadinovirus Unassigned Ictalurivirus The Herpesviridae are a family of DNA viruses that cause diseases in humans and animals. ... Aciclovir (INN) (IPA: ) or acyclovir (USAN, former BAN) is a guanine analogue antiviral drug used most commonly for the treatment of herpes simplex virus infection. ... Docosanol 10% cream is a topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). ... Famciclovir is an antiviral medicine that stops the varicella zoster virus that causes shingles. ... Fomivirsen (brand name Vitravene) is an antiviral drug. ... Foscarnet sodium (FoscavirÂ®, AstraZeneca) is an antiviral medication used to treat herpes viruses, including cytomegalovirus (CMV) and herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2). ... Ganciclovir sodium (CytoveneÂ®) is an antiviral medication used to treat cytomegalovirus (CMV) infections. ... Idoxuridine is an anti-herpesvirus antiviral drug. ... Penciclovir (INN) (IPA: ) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections. ... Trifluridine is an anti-herpesvirus antiviral drug, used primarily on the eye. ... Tromantadine Tromantadine is an antiviral medicine used to treat herpes simplex virus. ... Valaciclovir (INN) or valacyclovir (USAN) is an antiviral drug used in the management of herpes simplex and herpes zoster (shingles). ... Valganciclovir hydrochloride (ValcyteÂ®) is an antiviral medication used to treat cytomegalovirus infections. ... Chemical structure of vidarabine Vidarabine is an anti-viral drug which is active against herpes simplex and varicella zoster viruses. ... Influenza, commonly known as the flu, is an infectious disease of birds and mammals caused by an RNA virus of the family Orthomyxoviridae (the influenza viruses). ... Amantadine, 1-aminoadamantane, is an antiviral drug that was approved by the FDA in 1976 for the treatment of influenza type A in adults. ... Oseltamivir (INN) (IPA: ) is an antiviral drug used in the treatment and prophylaxis of both Influenzavirus A and Influenzavirus B. Like zanamivir, oseltamivir is a neuraminidase inhibitor. ... Please expand this article. ... Rimantadine (systematic name 1-(1-aminoethyl)adamantane) is an orally administered medicine used to treat, and in rare cases prevent, Influenzavirus A infection. ... Zanamivir is a neuraminidase inhibitor used in the treatment of and prophylaxis of both influenza A and influenza B. Zanamivir was the first neuraminidase inhibitor commercially developed. ... Antiretroviral drugs are medications for the treatment of infection by retroviruses, primarily HIV. Different classes of antiretroviral drugs act at different stages of the HIV life cycle. ... Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection. ... Abacavir (ABC) is extremely potent reverse transcriptase inhibitor, meant for the treatment of AIDS. ABC is capable of crossing the blood-brain barrier. ... Didanosine (2-3-dideoxyinosine, ddI) is sold under the trade names VidexÂ® and Videx ECÂ®. It is a reverse transcriptase inhibitor, effective against HIV and usually used in combination with other antiviral drug therapy as part of highly active antiretroviral therapy (HAART). ... Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) for the treatment of HIV infection in adults. ... Lamivudine (2,3-dideoxy-3-thiacytidine, 3TC) is a potent reverse transcriptase inhibitor of the class nucleoside analog reverse transcriptase inhibitor (NARTI). ... Stavudine (2-3-didehydro-2-3-dideoxythymidine, d4T, brand name ZeritÂ®) is a thymidine analogue active against HIV. It is phosphorylated by cellular kinases into active triphosphate. ... Zalcitabine (2-3-dideoxycytidine, ddC), is a derivative of the naturally existing deoxycytidine, made by replacing the hydroxyl group in position 3 with a hydrogen. ... Zidovudine (INN) or azidothymidine (AZT) (also called ZDV) is an antiretroviral drug, the first one approved for treatment of HIV. It is also sold under the names RetrovirÂ® and RetrovisÂ®, and as an ingredient in CombivirÂ® and TrizivirÂ®. It is an analog of thymidine. ... Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection. ... Tenofovir disoproxil fumarate belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NtRTIs), which block reverse transcriptase, an enzyme crucial to viral production in HIV-infected people. ... Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection. ... This article needs to be cleaned up to conform to a higher standard of quality. ... Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection. ... This article or section contains information that has not been verified and thus might not be reliable. ... Protease inhibitors are a class of medication used to treat or prevent viral infections. ... Amprenavir (AgeneraseÂ®) is a protease inhibitor used to treat HIV. It was approved by the FDA on April 15, 1999, for twice-a-day dosing instead of needing to be taken every eight hours. ... Categories: Stub ... Darunavir, sold as PrezistaÂ®, is a protease inhibitor used to treat HIV. It was approved by the Food and Drug Administration (FDA) on June 23, 2006. ... Fosamprenavir calcium (LexivaÂ®) is a pro-drug of the protease inhibitor and antiretroviral drug amprenavir. ... Categories: Possible copyright violations ... Lopinavir (ABT-378) is an antiretroviral of the protease inhibitor class. ... Nelfinavir (ViraceptÂ®) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV). ... Ritonavir is a drug from the protease inhibitor class used to treat AIDS. It is manufactured as Norvir® by Abbott Laboratories. ... Saquinavir (FortovaseÂ®, Roche) is a protease inhibitor, used as a component of HIV therapy. ... Tipranavir is a new protease inhibitor (PI) that was approved by the FDA in June 2005. ... A fusion inhibitor is a class of drugs used to treat HIV. External Links Fusion Inhibitor Resource Center Categories: Medical treatment stubs ... Enfuvirtide is a novel antiretroviral drug used in combination therapy for the treatment of HIV-1 infection. ... Adefovir dipivoxil, previously called bis-POM PMEA, is an orally-administered nucleotide analogue reverse transcriptase inhibitor (NtRTI), which works by blocking DNA polymerase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. ... Fomivirsen (brand name Vitravene) is an antiviral drug. ... Imiquimod (Aldaraâ„¢) is a prescription medication used to treat certain diseases of the skin, including skin cancer (malignant melanoma and actinic keratosis) as well as genital warts. ... Chemical structure of inosine. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... Podophyllin is a drug obtained from the rhizome of the American Mayapple (â€˜â€™Podophyllum peltatumâ€™â€™), an herbaceous perennial belonging to the natural order Berberidaceae, indigenous in woods in Canada and the United States. ... Ribavirin (CopegusÂ®; RebetolÂ®; RibasphereÂ®; VilonaÂ®,VirazoleÂ®, also generics from Sandoz, Teva, Warrick) is an anti-viral drug which is active against a number of DNA and RNA viruses. ... Viramidine (ICN 3142) is an anti-viral drug in Phase III human trials, but not yet approved for pharmaceutical use. ...