Cinq-Mars was the son of Marshal Antoine Coiffier-Ruzé, marquis d'Effiat, a close friend of Richelieu, who took the boy under his protection on his father's death in 1632.
In 1642, Louis had no "favourite" (a close friend, usually a lover at court, who usually had a major influence on the King's decisions). Richelieu had introduced the young Cinq-Mars, to Louis, hoping Louis would take Cinq-Mars as a lover. The cardinal believed Cinq-Mars was easy to control. Instead, the marquis tried to convince the king to have Richelieu executed, and when Cinq_Mars took matters into his own hands, Richelieu had him imprisoned and then beheaded in Lyon, together with François de Thou. Although the king approved the execution, the death of Cinq-Mars appears to have driven a wedge between him and the cardinal.