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Encyclopedia > Clinical biochemistry

Chemical pathology (also known as clinical biochemistry or clinical chemistry) is the area of pathology that is generally concerned with analysis of bodily fluids.


The discipline originated in the late 19th century with the use of simple chemical tests for various components of blood and urine. Subsequently other techniques were applied including the use and mesurement of enzyme activities, spectrophotometry, electrophoresis and immunoassay.


Most current laboratories are now highly automated and use assays that are closely monitored and quality controlled.


Tests that actually look at the cells of blood, as well as blood clotting studies are not included as this are usually grouped under haematology.


All biochemical tests come under chemical pathology. These are usually performed on serum, (the yellow watery part of blood that is left after cells are removed).


A large laboratory will accept up to about 700 tests. Even the largest of laboratories rarely does all these these tests themselves and some need to be referred to other labs.


This large array of tests can be further sub-categorised into sub specialities of:

Common Chemical Pathology tests are listed below

Sodium Potassium Chloride
Bicarbonate Urea Creatinine
Calcium Phosphate Albumin
Bilirubin AST ALT
GGT Alkaline phosphatase Magnesium
Osmolality Urate Iron
Transferrin Total protein Globulins
Glucose C-reactive protein HbA1c

See also



  Results from FactBites:
 
ACBI -- some definitions (496 words)
"Clinical biochemistry" is for most purposes synonymous with "clinical chemistry" and "chemical pathology".
Such designations as clinical biochemistry and chemical pathology cover the same field and, in practice, there are substantial overlaps between clinical chemistry and other clinical laboratory sciences, especially haematology, immunology, physiology and pharmacology (Dybkær 1984, p.11).
Clinical chemistry is thus a discipline which is inseparable from modern medicine, and is implicated in fundamental clinical and pathophysiological research (IFCC Handbook 1991-1993:6).
  More results at FactBites »


 

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