Clomiphine Citrate (Clomid) is a compound that is very similar in structure to estrogen.
Polycystic ovarian disease and obesity may decrease the response to Clomid, however this is unpredictable and a starting dose of 50 mg is still recommended.
Since Clomid is a drug used for controlled ovarian hyperstimulation (COH), it may be combined with intercourse, cup inseminations, or intrauterine insemination.
Clomid clinical use is therefore to oppose the negative feedback of estrogens on the hypothalamic-pituitary-ovarian axis, which enhances the release of LH and FSH.
Clomid and HCG are also occasionally used periodically during a steroid cycle, in an effort to prevent natural testosterone levels from diminishing.
Clomid can likewise also be used as a maintenance anti-estrogen throughout the duration of steroid intake with good confidence, just as is done with Nolvadex.
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