In 1516, King François I invited Leonardo da Vinci to Amboise and provided him with the Clos_Lucé as a place to stay and to work. Da Vinci, a famous painter and inventor, arrived with three samples of his painting, namely the Mona Lisa, Sainte Anne, and Saint Jean Baptiste. Da Vinci lived at the Clos-Lucé for the last three years of his life until his death on May 2, 1519.
Today, the Clos-Lucé mansion is a museum that reflects the prestigious history of the region and includes forty models of the various machines designed by da Vinci.