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Encyclopedia > Coagulase

Coagulase is an enzyme produced by Staphylococcus aureus to localize an area of residence that converts fibrinogen to fibrin. In laboratory, it is used to distinguish between different types of Staphylococcus isolates. Coagulase negativity excludes S. aureus. Ribbon diagram of the enzyme TIM, surrounded by the space-filling model of the protein. ... Binomial name Staphylococcus aureus Rosenbach 1884 Staphylococcus aureus, the most common cause of staph infections, is a spherical bacterium, frequently living on the skin or in the nose of a healthy person, that can cause a range of illnesses from minor skin infections (such as pimples, boils, and cellulitis) and... Fibrin is a protein involved in the clotting of blood. ... For other uses of lab, see Lab. ... Species S. aureus S. caprae S. epidermidis S. haemolyticus S. hominis S. lugdunensis S. saprophyticus S. warneri S. xylosus Staphylococcus (in Greek staphyle means bunch of grapes and coccos means granule) is a genus of Gram-positive bacteria. ...


Coagulase reacts with prothrombin in the blood. The resulting complex is called staphylothrombin, which causes blood to clot by converting fibrinogen to fibrin. Some coagulase is tightly bound to the surface of the bacteria S. aureus and coats its surface with fibrin upon contact with blood. Fibrin-coated staphylococci resist phagocytosis making the bacteria more virulent. Bound coagulase is part of the larger family of MSCRAMMS Thrombin (activated Factor II) is a coagulation protein that has many effects in the coagulation cascade. ...


The coagulase test is used to differentiate Staphylococcus aureus from the other species of Staphylococcus. The test uses rabbit plasma that has been inoculated with a staphylococcal colony. The tube is then incubated at 37 degrees Celsius for 1-1/2 hours. If positive (i.e. the suspect colony is S. aureus), the serum will coagulate, resulting in a clot (sometimes the clot is so pronounced that the liquid will completely solidify). If negative (i.e. the suspect colony is S. epidermidis), the plasma remains liquid. Binomial name Staphylococcus aureus Rosenbach 1884 Staphylococcus aureus, the most common cause of staph infections, is a spherical bacterium, frequently living on the skin or in the nose of a healthy person, that can cause a range of illnesses from minor skin infections (such as pimples, boils, and cellulitis) and... Binomial name Staphylococcus epidermidis (Winslow & Winslow 1908) Evans 1916 Staphylococcus epidermidis is a member of the bacterial genus Staphylococcus, consisting of Gram-positive cocci arranged in clusters. ...


Coagulase is what turns milk into yogurt.


  Results from FactBites:
 
Coagulase - Wikipedia, the free encyclopedia (199 words)
Coagulase is an adhesin (EC 3.4.23.48) produced by Staphylococcus aureus to localize an area of residence that converts fibrinogen to fibrin.
Coagulase is not an enzyme, despite its ending ("-ase").
Some coagulase is tightly bound to the surface of the bacteria S. aureus and coats its surface with fibrin upon contact with blood.
BD - Diagnostic Systems: Coagulase Plasma (820 words)
Coagulase binds plasma fibrinogen, causing the organisms to agglutinate or plasma to clot.
Coagulase Plasma, Rabbit is lyophilized rabbit plasma with 0.85% sodium citrate and 0.85% sodium chloride, approximately.
Coagulase Plasma, Rabbit with EDTA is lyophilized rabbit plasma with 0.15% EDTA (ethylenediaminetetraacetic acid) and 0.85% sodium chloride, approximately.
  More results at FactBites »


 

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