Coccidioidomycosis
Classification & external resources | | | Histopathological changes in a case of coccidioidomycosis of the lung showing a large fibrocaseous nodule. | | ICD-10 | B38 | | ICD-9 | 114 | | MedlinePlus | 001322 | | eMedicine | med/103 ped/423 | Coccidioidomycosis (also known as Valley fever, California valley fever, and (incorrectly) coccidiomycosis) is a fungal disease caused by Coccidioides immitis or C. posadasii.[1] It is endemic in certain parts of Arizona, California, Nevada, New Mexico, Texas, Utah and northwestern Mexico.[2] Image File history File links Size of this preview: 800 × 536 pixel Image in higher resolution (2876 × 1927 pixel, file size: 5. ...
Histopathology is a field of pathology which specialises in the histologic study of diseased tissue. ...
The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...
The following codes are used with International Statistical Classification of Diseases and Related Health Problems. ...
The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...
The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ...
MedlinePlus (medlineplus. ...
eMedicine is an online clinical medical knowledge base that was founded in 1996. ...
Divisions Chytridiomycota Zygomycota Glomeromycota Ascomycota Basidiomycota Deuteromycota Fungi (singular fungus) are a kingdom of eukaryotic organisms. ...
Binomial name Coccidioides immitis G.W. Stiles Sputum culture of Coccidioides immitis on Sabourauds medium, showing white, cottony fungus growth. ...
In epidemiology, an infection is said to be endemic in a population when that infection is maintained in the population without the need for external inputs. ...
Official language(s) English Capital Phoenix Largest city Phoenix Area Ranked 6th - Total 113,998 sq mi (295,254 km²) - Width 310 miles (500 km) - Length 400 miles (645 km) - % water 0. ...
Official language(s) English Capital Sacramento Largest city Los Angeles Area Ranked 3rd - Total 158,302 sq mi (410,000 km²) - Width 250 miles (400 km) - Length 770 miles (1,240 km) - % water 4. ...
This article does not adequately cite its references or sources. ...
Capital Santa Fe Largest city Albuquerque Area Ranked 5th - Total 121,665 sq mi (315,194 km²) - Width 342 miles (550 km) - Length 370 miles (595 km) - % water 0. ...
Official language(s) No Official Language See languages of Texas Capital Austin Largest city Houston Area Ranked 2nd - Total 261,797 sq mi (678,051 km²) - Width 773 miles (1,244 km) - Length 790 miles (1,270 km) - % water 2. ...
Official language(s) English Capital Salt Lake City Largest city Salt Lake City Area Ranked 13th - Total 84,876 sq mi (219,887 km²) - Width 270 miles (435 km) - Length 350 miles (565 km) - % water 3. ...
C. immitis resides in the soil in certain parts of the southwestern United States, northern Mexico, and a few other areas in the Western Hemisphere. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, which are a form of spore. The disease is not transmitted from person to person. C. immitis is a dimorphic saprophytic organism that grows as a mycelium in the soil and produces a sherule form in the host organism. The geographical western hemisphere of Earth, highlighted in yellow. ...
Arthroconidia are a type of fungal spores typically produced by segmentation of pre-existing fungal hyphae. ...
This article is about a biological reproductive structure; for the video game, see Spore (video game). ...
Mycelium is the vegetative part of a fungus consisting of a mass of branching threadlike hyphae that exists below the ground or within another substrate. ...
Symptomatic infection (40% of cases) usually presents as an influenza-like illness with fever, cough, headaches, rash, and myalgia (muscle pain).[3] Some patients fail to recover and develop chronic pulmonary infection or widespread disseminated infection (affecting meninges, soft tissues, joints, and bone). Severe pulmonary disease may develop in HIV-infected persons.[4] Influenza, commonly known as flu, is an infectious disease of birds and mammals caused by an RNA virus of the family Orthomyxoviridae (the influenza viruses). ...
A typical rash A rash is a change in the skin which affects its appearance or texture. ...
Myalgia means muscle pain and is a symptom of many diseases and disorders. ...
The meninges (singular meninx) are the system of membranes that envelop the central nervous system. ...
Species Human immunodeficiency virus 1 Human immunodeficiency virus 2 Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immunodeficiency syndrome (AIDS, a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. ...
 Geographic distribution of coccidioidomycosis. Image File history File links Size of this preview: 492 × 599 pixel Image in higher resolution (2020 × 2460 pixel, file size: 327 KB, MIME type: image/png)Geographic distribution of Coccidioidomycosis. ...
Image File history File links Size of this preview: 492 × 599 pixel Image in higher resolution (2020 × 2460 pixel, file size: 327 KB, MIME type: image/png)Geographic distribution of Coccidioidomycosis. ...
Biological Warfare
C. immitis was investigated by the United States during the 1950s and 1960s as a potential biological weapon.[citation needed] The Cash strain received the military symbol OC, and original hopes were for its use as an incapacitant. As medical epidemiology later made clear, OC would have lethal effects on several segments of the population, so it was later considered a lethal agent. It was never standardized, and beyond a few field trials, it was never weaponized. Most military work on OC was on vaccines by the mid-1960s.
Diagnostic test The fungal infection can be demonstrated by mycroscopic detection of diagnostic cells in body fluids, exudates, sputum and biopsy-tissue. With specific nucleotide primers C.immitis DNA can be amplified by PCR. It can also be detected in culture by morphological identification or by using molecular probes that hybridize with C.immitis RNA. An indirect demonstration of fungal infection can be achieved also by serologic analysis detecting fungal antigen or host antibody produced against the fungus. Sputum is matter that is coughed up from the respiratory tract, such as mucus or phlegm, mixed with saliva and then expectorated from the mouth. ...
Brain biopsy A biopsy (in Greek: bios = life and opsy = look/appearance) is a medical test involving the removal of cells or tissues for examination. ...
A nucleotide is a chemical compound that consists of a heterocyclic base, a sugar, and one or more phosphate groups. ...
The structure of part of a DNA double helix Deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic instructions for the development and function of living organisms. ...
Wikipedia does not yet have an article with this exact name. ...
This article or section does not adequately cite its references or sources. ...
An antigen is a substance that stimulates an immune response, especially the production of antibodies. ...
Each antibody binds to a specific antigen; an interaction similar to a lock and key. ...
Popular culture The illness is mentioned in episode 3x04 of the TV Show House, as the cause of a young girl's loss of inhibition. The illness does not actually cause loss of inhibition, nor does it cause milky tears. This was not a factual error in the episode: House was tricking the girl, however this was not obvious to many viewers. Lines in the Sand is the fourth episode of the third season of House and the fiftieth episode overall. ...
House, also known as House M.D., is a critically-acclaimed American medical drama television series created by David Shore and executive produced by film director Bryan Singer. ...
It is also the center of an episode of Bones (1x09), The Man In the Fallout Shelter. After being exposed to the fungus, the team was quarantined over Christmas to determine whether or not they had become infected. Errorneously claimed to be contagious from person to person. Bones is a current crime drama television series on the FOX Network. ...
References - ^ Walsh TJ, Dixon DM (1996). Spectrum of Mycoses. In: Baron's Medical Microbiology (Baron S et al, eds.), 4th ed., Univ of Texas Medical Branch. (via NCBI Bookshelf) ISBN 0-9631172-1-1.
- ^ Hector R, Laniado-Laborin R (2005). "Coccidioidomycosis--a fungal disease of the Americas.". PLoS Med 2 (1): e2. PMID 15696207.
- ^ Ryan KJ; Ray CG (editors) (2004). Sherris Medical Microbiology, 4th ed., McGraw Hill, pp. 680-83. ISBN 0838585299.
- ^ Ampel N (2005). "Coccidioidomycosis in persons infected with HIV type 1.". Clin Infect Dis 41 (8): 1174-8. PMID 16163637.
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