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Encyclopedia > Congenital amputation

Congenital amputation is a congenital disorder caused by fibrous bands of the amnion that constrict foetal limbs to such an extend, that they fall off due to missing blood supply. The child is born without one or more limbs or without parts of limbs (amelia). A congenital disorder is a medical condition that is present at birth. ... Amniotic band syndrome (ABS, also called amniotic band constriction, congenital constriction bands or rings, congential amputation, ADAM syndrome) is a congenital disorder caused by entrapment of fetal parts (usually a limb or digits) in fibrous amniotic bands while in utero. ... Foetus can refer to: a fetus, an embryo in later stages of development Foetus, a band fronted by industrial music pioneer J.G. Thirlwell. ... Amelia is the birth defect of lacking one or more limbs. ...


Causes

The inner fetal membrane (amnion) ruptures without injury to the outer membrane (chorion). Fibrous bands from the ruptured amnion float in the amniotic fluid and can entangle the fetus, reducing blood supply of limbs to such an extend, that they fall of and get absorbed in the amniotic fluid. Amnion ruptures might be caused by: For the alien race in Stephen Donaldsons The Gap Cycle, see Amnion (Gap Cycle). ... For the entertainment company see Chorion (company) The chorion surrounds the embryo and other membranes. ...

// Teratogenesis is a medical term from the Greek, literally meaning monster-birth, which derives from teratology, the study of the frequency, causation, and development of congenital malformations—misleadingly called birth defects. ... // Thalidomide is a sedative, hypnotic, and anti-inflammatory medication. ... Phocomelia (from Greek φoko = seal plus μέλος (plural μέλεα) = limb) is a congenital disorder involving the limbs (dysmelia), that presents at birth very short or absent long bones and flipper-like appearance of hands and sometimes feet. ... The mushroom cloud of the atomic bombing of Nagasaki, Japan, in 1945 lifted nuclear fallout some 18km (60,000 feet) above the epicenter. ... Radioiodine is the common name for iodine-131, a radioisotope of iodine. ... Clinac 2100 C100 accelerator Radiation therapy (or radiotherapy) is the medical use of ionizing radiation as part of cancer treatment to control malignant cells (not to be confused with radiology, the use of radiation in medical imaging and diagnosis). ... Trauma can represent: Physical trauma, an often serious and body-altering physical injury, such as the removal of a limb. ...

Treatment

In rare cases, if diagnosed in utero, fetal surgery may be considered to save a limb which is in danger of amputation. Open fetal surgery is an invasive form of fetal intervention in the treatment of birth defects where the uterus is opened up for direct surgery on the fetus. ... Partial hand amputation For the song Amputations by Death Cab for Cutie, see You Can Play These Songs with Chords Amputation is the removal of a body extremity by trauma (also referred to as avulsion) or surgery. ...


Literature

  • Gabos PG. (Department of Orthopedic Surgery, Alfred I. duPont Hospital for Children, Wilmington, DE 19899, USA) Modified technique for the surgical treatment of congenital constriction bands of the arms and legs of infants and children Orthopedics. 2006 May;29(5):401-4
  • Walter JH Jr, Goss LR, Lazzara AT. (Department of Orthopedics, Pennsylvania College of Podiatric Medicine, Philadelphia 19107, USA.) Amniotic band syndrome J Foot Ankle Surg. 1998 Jul-Aug;37(4):325-333
  • Light TR, Ogden JA. (Dept. of Orthopaedic Surgery, Loyola University School of Medicine, Maywood, Illinois 60153, USA) Congenital constriction band syndrome. Pathophysiology and treatment Yale J Biol Med. 1993 May-Jun;66(3):143-155
  • Further literature available e.g. via PubMed, free medical literature database of the US health authority (search for: congenital amputation or amniotic band or congenital constriction bands or other synonyms) via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed


 

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