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The coxsackie viruses are divided into two major subgroups, labeled A and B. There are 23 known coxsackie A viruses that usually cause only enteric diseases, and 6 known coxsackie B viruses, which are the ones of greatest concern because of their ability to cause serious diseases beyond the intestinal tract.
Coxsackie B viruses are estimated to be responsible for at least 50% of the cases of infection-caused heart diseases.
Coxsackie infections are recognized as health problems in modern China, contributing to the high rates of childhood intestinal disease, meningitis, and, for adults, myocarditis.
The settlement of Coxsackie began in the 17th Century, around 1652 as part of the development of New Netherlands.
The area became a district in 1772, and the Town of Coxsackie was founded in 1788.
Further land was lost in the formation of the newer Towns of Cairo and Greenville, Greene County, NewYork (1803), New Baltimore (1811), and Athens in 1815.
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