A crossover trial is one where patients are given all of the medications to be studied in random order. These studies are generally done on patients with chronic diseases to control their symptoms. They cannot determine long term effects or use drugs that can cure the disease. The data is analyzed according to the original intention to treat.
Randomization is the process of making something random. ... Medicine is the branch of health science and the sector of public life concerned with maintaining human health or restoring it through the treatment of disease and injury. ... One may be faced with the problem of making a definite decision with respect to an uncertain hypothesis which is known only through its observable consequences. ... The topics below are usually included in the area of interpreting statistical data. ... Evidence-based medicine (EBM) is a medical movement based upon the application of the scientific method to medical practice, recognizing that many long-established medical traditions are not yet subjected to adequate scientific scrutiny. ... Systematic reviews are named as the highest level of medical evidence, by evidence based medicine professionals. ... A meta-analysis is a statistical practice of combining the results of a number of studies. ... Double-blind describes an especially stringent way of conducting an experiment, usually on living, conscious, human subjects. ... A randomized contro // Headline text lInsert non-formatted text hereled trial (RCT) is a form of clinical trial, or scientific procedure used in the testing of the efficacy of == medicines oBold textreliable form of scientific evidence because [[ == it is the best known designr medical procedures. ...
References
Bland M and Peacock J (2004). Statistical Questions in Evidence Based Medicine. New York: Oxford University Press. ISBN 0-19-262992-1