Curling's ulcer is an acutepeptic ulcer of the duodenum resulting as a complication from severe burns when reduced plasma volume leads to sloughing of the gastric mucosa. The condition was first described in 1823 and named for a doctor, Thomas Blizard Curling, who observed ten such patients in 1842.[1] In medicine, an acute disease is a disease with either or both of: a rapid onset; a short course (as opposed to a chronic course). ... A benign gastric ulcer (from the antrum) of a gastrectomy specimen. ... In anatomy of the digestive system, the duodenum is a hollow jointed tube connecting the stomach to the jejunum. ... Blood plasma is the liquid component of blood, in which the blood cells are suspended. ... The gastric mucosa the mucous membrane layer of the stomach which contains the glands and the gastric pits. ... Thomas Blizard Curling (1811-1888), British surgeon, was born in London in 1811. ...
These stress ulcers were once a common complication of serious burns, presenting in over 10% of cases,[1] and especially common in child burn victims.[2] They result in perforation and hemorrhage more often than other forms of intestinal ulceration[3] and had correspondingly high mortality rates.[1] While emergency surgery was once the only treatment, combination therapies including enteral feeding with powerful antacids such as H2-receptor antagonists or, more recently, proton pump inhibitors such as omeprazole have made Curling's ulcer a rare complication.[4] To meet Wikipedias quality standards, this article or section may require cleanup. ... A feeding tube is a medical device used to provide nutrition to patients who cannot or refuse to (cf. ... An H2-receptor antagonist, often shortened to H2-antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. ... Proton pump inhibitors are a group of drugs whose main action is pronounced and long-lasting reduction of gastric acid production. ... Omeprazole (INN) (IPA: ) is a proton pump inhibitor (brand names Antra® in Italy) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome. ...
A similar condition involving elevated intracranial pressure is known as Cushing ulcer. A Cushing ulcer is a gastric ulcer produced by elevated intracranial pressure. ...
References
^ abc Pruitt, Basil A., Jr., F.D. Foley and John A. Moncrief (Oct 1970). "Curling's Ulcer:A Clinical-Pathology Study of 323 Cases". Annals of Surgery172.
^ Bruck, H.M. and Basil A. Pruitt, Jr. (Jun 1972). "Curling's ulcer in children: a 12-year review of 63 cases". Journal of Trauma12.
^ Lev, Robert et al. (Dec 1973). "Stress erosions". Digestive Diseases and Sciences18.
^ Moran, K.T., T. O'Reilly and A.M. Munster (Oct 1987). "A combined regimen for the prophylaxis of Curling's ulcer". American Surgeons53.
A peptic ulcer is one that occurs in the upper digestive tract.
An ulcer (from Latin ulcus) is an open sore of the skin, eyes or mucous membrane, often caused by an initial abrasion and generally maintained by an inflammation and/or an infection.
The ulcer is superficial and presents as an abrasion, blister, or wound with a shallow center.
An ulcer (from Latin ulcus) is an open sore of the skin, eyes or mucous membrane, often caused, but not exclusively, by an initial abrasion and generally maintained by an inflammation, an infection, and/or medical conditions which impede healing.
Ulcers are healing wounds that develop on the skin, mucous membranes or eye.
Peptic ulcer (of the stomach, esophageal cardium or duodenum)
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