 | | Cycloserine | | Systematic (IUPAC) name | | 4-aminoisoxazolidin-3-one | | Identifiers | | CAS number | 68-41-7 | | ATC code | J04AB01 | | PubChem | 401 | | DrugBank | APRD00894 | | Chemical data | | Formula | C3H6N2O2 | | Mol. weight | 102.092 g/mol | | Pharmacokinetic data | | Bioavailability | ? | | Metabolism | ? | | Half life | ? | | Excretion | ? | | Therapeutic considerations | | Pregnancy cat. | ? Image File history File links Cycloserine. ...
IUPAC nomenclature is a systematic way of naming organic chemical compounds. ...
CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ...
The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
PubChem is a database of chemical molecules . ...
DrugBank is a database available at the University of Alberta that provides information about thousands of products. ...
A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ...
The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
It has been suggested that this article or section be merged with cell metabolism and carbohydrates. ...
The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ...
Excretion is the biological process by which an organism chemically separates waste products from its body. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
| | Legal status | | | Routes | ? | This does not cite its references or sources. Please help improve this article by introducing appropriate citations. (help, get involved!) This article has been tagged since June 2006. It is oral broad spectrum antibiotic effective against tuberculosis, it inhibits cell wall synthesis of TB bacilli at early stage of peptidoglycan synthesis. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...
In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
Staphylococcus aureus - Antibiotics test plate. ...
Being trialed for treatment of phobias as well as an adjuvant to conventional treatments for depression and schizophrenia. The term phobia, which comes from the Ancient Greek word for fear (φόβος, fobos), denotes a number of psychological and physiological conditions that can range from serious disabilities to common fears to minor quirks. ...
Clinical depression (also called major depressive disorder) is a state of intense sadness, melancholia or despair that has advanced to the point of being disruptive to an individuals social functioning and/or activities of daily living. ...
Side effects mainly CNS manifestations i.e. headache, irritability, depression, convulsions. Co-administration of pyridoxine can reduce the incidence of some of the CNS side effects(e.g. convulsions). A headache (medically known as cephalalgia, sometimes spelled as cephalgia) is a condition of pain in the head; sometimes neck or upper back pain may also be interpreted as a headache. ...
Depression, or a depressed mood, may in everyday English refer to a state of melancholia, unhappiness or sadness, or to a relatively minor downturn in mood that may last only a few hours or days. ...
Pyridoxine is one of the compounds that can be called vitamin B6, along with Pyridoxal and Pyridoxamine. ...
These psychotropic responses are related to D-cycloserine's action as a partial agonist of the neuronal NMDA receptor for glutamate and have been examined in implications with sensory-related fear extinction in the amygdala. See Michael Davis, Barbara Rothbaum, Kerry Ressler et al. and their work with PTSD at Emory University's School of Medicine. [1] Agonists An agonist is a substance that binds to a receptor and triggers a response in the cell. ...
The NMDA receptor (NMDAR) is an ionotropic receptor for glutamate (NMDA (N-methyl d-aspartate) is a name of its selective specific agonist). ...
Glutamate is the anion of glutamic acid. ...
Extinction in psychology refers to extinction of conditional reflexes when a reinforcement is witheld. ...
This article or section does not cite its references or sources. ...
Michael Davis is a philosopher of law and ethics, author, and Professor of Philosophy, currently at the Illinois Institute of Technology. ...
Barbara Rothbaum, Ph. ...
Posttraumatic stress disorder (PTSD), is a term for the psychological consequences of exposure to or confrontation with stressful experiences, which involve actual or threatened death, serious physical injury or a threat to physical integrity and which the person found highly traumatic. ...
Emory University is a private university in the city of Atlanta, Georgia. ...
References
- ^ Picower Institute speakers (2005). "EChange Your Mind: Memory and Disease — Worldwide". MIT World Video Archive.
| Antimycobacterials (J04) edit | | Tuberculosis: | Aminosalicylic acid, Calcium aminosalicylate, Capreomycin, Cycloserine, Ethambutol, Ethionamide, Isoniazid, Morinamide, Protionamide, Pyrazinamide, Rifabutin, Rifampicin, Rifamycin, Rifapentin, Sodium aminosalicylate, Terizidone, Tiocarlide Species See below. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
Tuberculosis (abbreviated as TB for Tubercle Bacillus) is a common and deadly infectious disease caused by the bacterium Mycobacterium tuberculosis, which most commonly affects the lungs (pulmonary TB) but can also affect the central nervous system, lymphatic system, circulatory system, genitourinary system, bones and joints. ...
Aminosalicylic acid (C7H7NO3) is also known as para-aminosalicylic acid, p-aminosalicylic acid or 4-aminosalicylic acid; abbreviated 4-ASA, PAS or P. It is sold in the US by Jacobus Pharmaceutical as Paser®. 5-aminosalicylic acid is a closely related compound that also has medical uses. ...
A peptide Antibiotic which is given in combination with other antibiotics in tuberculosis adverse effects includes nephrotoxicity and 8th cranial nerve toxicity. ...
A bacteriostatic antimycobacterial prescribed to treat Tuberculosis (Mycobacterium). ...
Ethionamide (2-ethylthioisonicotinamide, Trecator SC®) is an antibiotic used in the treatment of tuberculosis. ...
Isoniazid (also called isonicotinyl hydrazine or isonicotinic acid hydrazide); abbreviated INH or just H. Isoniazid is a first-line antituberculous medication used in the prevention and treatment of tuberculosis. ...
Pyrazinamide is an antituberculosis agent used to treat tuberculosis in afflicted patients. ...
Rifabutin is an antibiotic drug primarily used in the treatment of tuberculosis. ...
Rifampicin (INN) (IPA: ) or rifampin (USAN) is a bacteriocidal antibiotic drug of the rifamycin group. ...
The rifamycins are a group of antibiotics which are synthesized either naturally by the bacterium Amycolatopsis mediterranei, or artificially. ...
Rifapentin (or rifapentine) is an antibiotic used in the treatment of tuberculosis. ...
| | Leprosy: | Aldesulfone sodium, Clofazimine, Dapsone Leprosy, also known as Hansens disease,[1] is an infectious disease caused by a DNA plasmid (transposon, or ultravirus, a small circle of DNA) carried in Hansens bacillus (the Mycobacterium leprae bacterium) which is thus the vector. ...
Aldesulfone sodium (or sulfoxone) is an antibiotic used in the treatment of leprosy. ...
Clofazimine is a fat-soluble riminophenazine dye used for the treatment of leprosy. ...
Dapsone is an antibiotic medication most commonly used for the treatment of Mycobacterium leprae infections (leprosy). ...
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