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BioMed Central | Full text | Maize haplotype with a helitron-amplified cytidine deaminase gene copy (6341 words) |
 | Cytidine deaminases are a superfamily, which includes Cytidine deaminase, nucleoside deaminase, deoxycytidylate deaminase and riboflavin deaminase. |
| They are enzymes that de-aminate cytidine to uridine and play an important role in a variety of pathways from bacteria to man. Ancestral members of this superfamily were only able to de-aminate cytidine of mononucleotides or nucleosides. |
| The cytidine deaminase super-family can be classified into RNA-editing deaminases, cytidine deaminases, nucleoside deaminases and deoxycytidylate deaminases, based on substrate specificity and homology of the active-site sequence [26]. |
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Olympus MIC-D: Polarized Light Gallery - Cytidine (325 words) |
| Cytosine, the organic base of cytidine, was first isolated from the thymus of a calf in 1894 and was synthesized in the laboratory in 1903. |
| As a crystal, cytidine appears as a white or almost white powder and is available in a chemically synthesized regular or radiolabeled form. |
| The enzyme is used by geneticists and gene therapists for cutting and splicing DNA and RNA segments, and may explain somatic mutations and evolution by viral and bacterial vectors. |
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