Danaparoid sodium (Orgaran®) is an anticoagulant that works by inhibiting thrombin. It is used to prevent deep venous clots, particularly in situations with a high risk of clot formation, such as after hip surgery. It is also used in the treatment of heparin-induced thrombocytopenia. This drug is no longer marketed in the United States. An anticoagulant is a substance that prevents coagulation; that is, it stops blood from clotting. ... Thrombin (activated Factor II) is a coagulation protein that has many effects in the coagulation cascade. ... It has been suggested that Deep Vein Thrombosis be merged into this article or section. ... Bones of the Hip In anatomy, the hip is the bony projection of the femur, known as the greater trochanter, and the overlying muscle and fat. ... Heparin-induced thrombocytopenia (HIT) with or without thrombosis (HITT) is thrombocytopenia (low platelet counts) due to the administration of heparin. ...

Administration

IV In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...

Side effects

• Bleeding problems
• Low platelets, due to a low level of structural similarity between danaparoid and heparin
• Asthma exacerbations, due to allergies to sulphites contained within the medicine