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Encyclopedia > Dapsone

Dapsone chemical structure
Dapsone Image File history File links Dapsone. ...


IUPAC name
CAS number
80-08-0
ATC code
J04BA02
PubChem
2955
DrugBank
APRD00345
Chemical formula C12H12N2O2S
Molecular weight 248.302
Bioavailability  ?
Metabolism  ?
Elimination half-life  ?
Excretion  ?
Pregnancy category  ?
Legal status  ?
Routes of administration  ?

Dapsone is an antibiotic medication most commonly used for the treatment of Mycobacterium leprae infections (leprosy). Dapsone can also be used to treat dermatitis herpetiformis and other skin conditions. It is also sometimes used to prevent Pneumocystis carinii pneumonia (PCP) in patients with HIV and to treat Idiopathic thrombocytopenic purpura. IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... A section of the Anatomical Therapeutic Chemical Classification System. ... PubChem is a database of chemical molecules . ... DrugBank is a database available at the University of Alberta that provides information about thousands of products. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Santorio Santorio (1561-1636) in his steelyard balance, from Ars de statica medecina, first published 1614 Metabolism (from μεταβολισμος (metabolismos)) is the biochemical modification of chemical compounds in living organisms anggjgjhnd cell (b). ... The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ... Excretion is the biological process by which an organism chemically separates waste products from its body. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother. ... The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... An antibiotic is a drug that kills or slows the growth of bacteria. ... Binomial name Mycobacterium leprae Hansen, 1874 Mycobacterium leprae, also known as Hansen’s bacillus, is the bacterium that causes leprosy (Hansens disease). ... For the malady found in the Hebrew Bible, see the article Tzaraath. ... Dermatitis herpetiformis, or DH, is a skin disorder often associated with celiac disease. ... Pneumocystis jiroveci pneumonia or Pneumocystis pneumonia (PCP) is a form of pneumonia caused by a yeast-like fungal microorganism called Pneumocystis jiroveci (sometimes spelled jirovecii and formerly known as Pneumocystis carinii). ... Human immunodeficiency virus (commonly known as HIV, and formerly known as HTLV-III and lymphadenopathy-associated virus) is a retrovirus that primarily infects vital components of the human immune system such as CD4+ T cells, macrophages and dendritic cells. ... Idiopathic thrombocytopenic purpura is the condition of having a low platelet count (thrombocytopenia) of no known cause (idiopathic). ...


Dapsone is administered orally.


The primary side effect of this drug is anemia (hemolytic) and methemoglobinemia, though other side effects, including nausea, headache, and peripheral neuropathy have been known to occur in patients on this medication. This article discusses the medical condition. ... For other uses, see Nausea (disambiguation). ... A headache (medically known as cephalgia) is a condition of mild to severe pain in the head; sometimes neck or upper back pain may also be interpreted as a headache. ... Peripheral neuropathy is the medical term for damage to nerves of the peripheral nervous system, which may be caused either by diseases of the nerve or from the side-effects of systemic illness. ...


Dapsone is thought to act by depleting the body's stores of para-aminobenzoic acid (PABA). Para-Aminobenzoic acid (PABA) is a chemical used in sunscreen that is an essential nutrient for some bacteria. ...


External links

  • MedlinePlus Drug Information

  Results from FactBites:
 
dapsone - definition of dapsone in Encyclopedia (100 words)
Dapsone is an antibiotic medication most commonly used for the treatment of Mycobacterium leprae infections (leprosy).
Dapsone can also be used to treat dermatitis herpetiformis and other skin infections.
Dapsone is thought to act by depleting the body's stores of para-aminobenzoic acid (PABA).
  More results at FactBites »


 

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