David 'Davy' Adriaan van Dorp (Amsterdam April 27, 1915 - Vlaardingen February 19, 1995) was a Dutch chemist. Amsterdam Location Country The Netherlands Province North Holland Population 739. ... April 27 is the 117th day of the year (118th in leap years) in the Gregorian Calendar, with 248 days remaining. ... 1915 was a common year starting on Friday (see link for calendar). ... Vlaardingen is a city in South Holland in the Netherlands. ... February 19 is the 50th day of the year in the Gregorian Calendar. ... 1995 was a common year starting on Sunday of the Gregorian calendar. ...

Van Dorp was born as the son of Hendrik van Dorp and Maria van Dorp, and studied chemistry in Amsterdam where he received a PhD for his thesis Aneurine en gistphosphatase in 1941.

In 1946, while employed by the Dutch Organon company in Oss, Van Dorp and Jozef Ferdinand Arens ('Coco') published the synthesis for vitamin A acid in the scientific journal Nature. In 1947, they completed the first full synthesis for the complex compound vitamin A, by taking the final step and turning the acid in an alcohol. Their synthesis was not to be used for commercial production, as an alternative route that was published soon after by Otto Isler and co-workers (Hoffmann-La Roche) turned out to be much more suited for upscaling. The Organon is the name given by Aristotles followers, the Peripatetics, for the standard collection of six of his works on logic. ... For the Icelandic Óss rune ᚨ, see Aesir. ... Retinol, the dietary form of vitamin A, is a fat-soluble, antioxidant vitamin important in vision and bone growth. ... Hoffmann-La Roche, Ltd. ...

Van Dorp joined the Unilever Research Laboratory in Vlaardingen in 1959, and was a key person in the studies regarding the role of arachidonic acid in the metabolic pathway to prostaglandin E2, in close cooperation with Sune K. Bergström who would later receive a Nobel prize for his work on prostaglandins. Unilever is an Anglo-Dutch company which owns many of the worlds consumer product brands in foods, beverages, cleaning agents and personal care products. ... Vlaardingen is a city in South Holland in the Netherlands. ... Arachidonic acid is a polyunsaturated fatty acid with four cis double bonds, which are the sources of its flexibility and give it the capacity to react with molecular oxygen. ... A prostaglandin is any member of a group of lipid compounds that are derived from fatty acids and have important functions in the animal body. ... Sune Karl Bergström (January 10, 1916 - August 15, 2004) was a Swedish biochemist. ... Photographs of Nobel Prize Medals. ...

References

• J.F. Arens, D.A. van Dorp, Nature 157, 190-191 (1946)
• D.A. van Dorp, J.F. Arens, Nature 160, 189 (1947)
• O. Isler, W. Huber, A. Ronco, M. Kofler, Helv. Chim. Acta 30, 1911-1927 (1947)
• D.A. van Dorp, R.K. Beerthuis, D.H. Nugteren, H. Vonkeman, Biochim. Biophys. Acta 90, 204-207 (1964)
• S. Bergström, H. Danielsson, B. Samuelsson, Biochim. Biophys. Acta 90, 207-210 (1964)

External link

• Bergströms scientific biography (http://nobelprize.org/medicine/laureates/1982/bergstrom-lecture.pdf)