Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus, (An Anatomical Exercise on the Motion of the Heart and Blood in Living Beings) is the best-known work of the physician William Harvey. The book was first published in 1628, and had an immediate and far-reaching influence on Harvey's contemporaries; Thomas Hobbes said that Harvey was the only modern author whose doctrines were taught in his lifetime. William Harvey William Harvey (April 1, 1578 – June 3, 1657) was an English medical doctor, who is credited with being the first to correctly describe, in exact detail, the properties of blood being pumped around the body by the heart. ... 1628 was a leap year starting on Saturday of the Gregorian calendar (or a leap year starting on Tuesday of the 10-day slower Julian calendar). ... “Hobbes” redirects here. ...

In the De motu cordis, Harvey investigated the effect of ligatures on blood flow. The book also argued that blood was pumped around the body in a "double circulation", where after being returned to the heart, it is recirculated in a closed system to the lungs and back to the heart, where it is returned to the main circulation. In medicine, a ligature is a device, similar to a tourniquet, usually of thread or string, tied around a limb, blood vessel or similar to restrict blood flow. ...

Synopsis

This work is one of the greatest and most famous contributions to physiology, for it introduces into biology the doctrine of the complete circulation of the blood. Partial anticipations of Harvey's great discovery go back to the thirteenth century, when the pulmonary or lesser circulation was proposed by Al-Nafis. In 1553, Michael Servetus said that blood flows from the heart to the lungs, and that it there mixes with air to form the arterial blood which flows back to the heart. Between 1570 and 1590, Cesalpino suggested, in a controversy with Galenists, that the movement of blood was more like a circulation than an oscillation; but this view lacks clarity. In 1603, Hieronymus Fabricius ab Acquapendente published a work clearly describing the valves in the veins and showing that they hinder the flow of blood away from the heart. From 1597 to 1602, Harvey studied arts and medicine at Padua, and made a careful study of the heart and the movement of blood. By 1616, he was presenting in lectures his case for the circulation of the blood, but it was not until 1628 that he published it in his classic work, De Motu Cordis et Sanguinis. This book is important both for the discovery of the complete circulation and for the experimental, quantitive and mechanistic methodology which Harvey introduced. He looked upon the heart, not as a mystical seat of the spirit and faculties, but as a pump analyzable along mechanical lines. He also measured the amount of blood which it sent out to the body. He observed that with each beat two ounces of blood leave the heart; so that with 72 heart beats per minute, the heart throws into the system 540 pounds of blood every hour. Where could all this blood come from? The answer seems to be that it is the same blood that is always returning. Moreover, the one-way valves in the heart, like those in the veins, indicate that, following the pulmonary circulation, the blood goes out to all parts of the body through the arteries and returns by way of the veins. The blood thus makes a complete closed circuit. As Harvey expressed it, "There must be a motion, as it were, in a circle." There was, however, one stage in the circulation which Harvey was not able to see - that in which the veins and arteries lose themselves by subdivision into the tiny capillary vessels. It was in 1660, three years after Harvey's death, that Marcello Malpighi saw the blood moving in the capillary vessels of the frog's lung, and thus supplied the missing link in Harvey's proof of the circulation of the blood. Ala-al-din abu Al-Hassan Ali ibn Abi-Hazm al-Qarshi al-Dimashqi (Arabic: علاء الدين أبو الحسن عليّ بن أبي حزم القرشي الدمشقي ) known as ibn Al-Nafis (Arabic: ابن نفيس ), was an Arab physician who is mostly famous for being the first to describe the pulmonary circulation of the blood. ... // Events June 26 - Christs Hospital in London gets a Royal Charter July 6 - Edward VI of England dies July 10 - Lady Jane Grey is proclaimed Queen of England - for the next nine days July 18 - Lord Mayor of London proclaims Queen Mary as the rightful Queen - Lady Jane Grey... Michael Servetus. ... Events January 23 - The assassination of regent James Stewart, Earl of Moray throws Scotland into civil war February 25 - Pope Pius V excommunicates Queen Elizabeth I of England with the bull Regnans in Excelsis May 20 - Abraham Ortelius issues the first modern atlas. ... Bold text{| align=right cellpadding=3 id=toc style=margin-left: 15px; |- | align=center colspan=2 | Years: 1587 1588 1589 - 1590 - 1591 1592 1593 |-vdsf gno[gldw[pvkijxaiamknn csogfhbvdowkhbfkqhjkhrjkhwgfhbjkpnkfokfgok3pkpk9pjhkt9erktyujkip9kijker9thhrkg9hkitr9gtkih9t0ykltk[u0jo0iey9uhyit90ertyhige9rity9riyh9ujirtyuhjnh-4e9tyigh9thiuy0h8tyh34tu8uy8u8u8u8rtu5y8ru8thu0tru0ut0rhutuh0trhu0hseogtrhr8uyhju8t89er9te9r8fy8shit ass dick bitch fuck | align=center colspan=2 | Decades: 1560s 1570s 1580s - 1590s - 1600s 1610s 1620s |- | align=center | Centuries... Girolamo Fabrizi d Acquapendente. ... A city and historical diocese in Italy. ... A valve is a mechanical device that regulates the flow of fluids (either gases, fluidised solids, slurries or liquids) by opening, closing, or partially obstructing various passageways. ... In biology, a vein is a blood vessel which carries blood toward the heart. ... The heart and lungs, from an older edition of Grays Anatomy. ... Events 17 January - A court case in Guildford recorded evidence that a certain plot of land was used for playing “kreckett” (i. ... This page is about the year. ... Tronco Maestro Riviera: a pedestrian walk along a section of the inland waterway or naviglio interno of Padua. ... Year 1616 (MDCXVI) was a leap year starting on Friday (link will display the full calendar) of the Gregorian calendar (or a leap year starting on Monday of the 10-day slower Julian calendar). ... 1628 was a leap year starting on Saturday of the Gregorian calendar (or a leap year starting on Tuesday of the 10-day slower Julian calendar). ... An electrically driven pump (electropump) for waterworks near the Hengsteysee, Germany. ... Pulmonary circulation is the portion of the cardiovascular system which carries oxygen-depleted blood away from the heart, to the lungs, and returns oxygenated blood back to the heart. ... Section of an artery An artery or arterial is also a class of highway. ... television cameras for surveillance. ... // Events January 1 - Colonel George Monck with his regiment crosses from Scotland to England at the village of Coldstream and begins advance towards London in support of English Restoration. ... Marcello Malpighi (March 10, 1628 - September 30, 1694) was an Italian doctor, who gave his name to several physiological features. ... Distribution of frogs (in black) Suborders Archaeobatrachia Mesobatrachia Neobatrachia - List of Anuran families The frog is an amphibian in the order Anura (meaning tail-less from Greek an-, without + oura, tail), formerly referred to as Salientia (Latin saltare, to jump). ...

Cultural influence

Harvey's De motu cordis plays a central role in the campus novel The Surleighwick Effect, written by the (pseudonymous) author Charles Cutting. In the novel, the only learned professor there bequeaths his books to Surleighwick University. The books are inspected by the venal and stupid Librarian and Vice-Chancellor. Finding one tatty old volume in which many words seem to end in 'u', they assume it is written in Romanian and discard it as being worthless. In fact it is an immensely valuable copy of the first edition of the De motu cordis, and much of the plot of the rest of novel turns on the vain efforts of these two contemptible figures to get the volume back. A campus novel is a novel whose main action is set in and around the campus of a university. ...

External links

• English translation of the book at Fordham University
• Exercitatio Anatomica de Motu Cordis et Sanguinis 1628. From Rare Book Room. Scanned first edition.