Decay accelerating factor is a protein involved in the complement system. Hugo is a masculine name. ... The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The National Center for Biotechnology Information (NCBI) is part of the US National Library of Medicine (NLM), which is a branch of the US National Institutes of Health. ... Swiss-Prot is a curated biological database of protein sequences created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute. ... The Protein Data Bank (PDB) is a repository for 3-D structural data of proteins and nucleic acids. ... The Enzyme Commission number (EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. ... In biology and evolutionary computation, a locus is the position of a gene (or other significant sequence) on a chromosome. ... Chromosome 1 is, by convention, the designation for the largest human chromosome. ... A complement protein attacking an invader. ...
Activators: C6 | C7 | C9 | MBL2 | PFC Complexes: C1Q (C1QA, C1QB, C1QG) | C3-convertase | C8 (C8A, C8B, C8G) | MAC Enzymes: BF | C1R | C1S | C2 | C3 | C4 | C5 | DF | MASP1 | MASP2 Inhibitors: C1inh | C4BP (C4BPA, C4BPB) | CLU | DAF | HF1 | IF | SERPING1 | VTN Receptors: C3AR1 | C5R1 | CR1 | CR2 | ITGAM Medical Subject Headings (MeSH) is a huge controlled vocabulary (or metadata system) for the purpose of indexing journal articles and books in the life sciences. ... A complement protein attacking an invader. ... Complement component 6 is a protein involved in the complement system. ... Complement component 7 is a protein involved in the complement system. ... Complement component 9 is a protein involved in the complement system. ... Complement component 1QA is a protein involved in the complement system. ... Complement component 1QB is a protein involved in the complement system. ... Complement component 1QG is a protein involved in the complement system. ... C3-convertase is the name of the enzyme composed of the C4b-C2b complex, which forms during the Classical pathyway of the complement system. ... Complement component 8A is a protein involved in the complement system. ... Complement component 8B is a protein involved in the complement system. ... Complement component 8G is a protein involved in the complement system. ... BF is a protein involved in the complement system. ... Complement component 1R is a protein involved in the complement system. ... Complement component 1S is a protein involved in the complement system. ... Complement component 2 is a protein involved in the complement system. ... In immunology, soluble C3-convertase, also known as iC3Bb, catalyzes the proteolytic cleavage of C3 into C3a and C3b as part of the alternative complement system. ... Complement component 5 is a protein involved in the complement system. ... DF is a protein involved in the complement system. ... C1-inhibitor (C1inh) is a serine protease inhibitor (serpin) protein, the main function of which is inhibition of the complement system. ... C4BP (Complement C4B-binding protein) can refer to: C4BPA (protein) C4BPB (protein) Category: ... C4BPA is a protein involved in the complement system. ... C4BPB is a protein involved in the complement system. ... Vitronectin is an abundant glycoprotein found in blood plasma and the extra cellular matrix. ... C3AR1 is a protein involved in the complement system. ... C5R1 is a protein involved in the complement system. ... Complement component receptor 1 is a protein involved in the complement system. ... Complement component receptor 2 is a protein involved in the complement system. ...
The glyco-inositol phospholipid (GIPL) anchoring moieties of decayacceleratingfactor (DAF) proteins expressed on human erythrocytes (E hu) and nucleated cells were structurally compared to determine the mechanism of their differing sensitivity to cleavage by phosphatidylinositol-specific phospholipase C (PI-PLC).
Gas chromatographic (GC) analyses of methanolyzed, silylated, and hydrolyzed/acetylated E hu DAF protein revealed 2.20 ± 0.16 mol of fatty acid, 0.86 ± 0.05 mol of inositol, and ∼1.0 mol of alkylglycerol per mol of protein.
These findings demonstrate that DAF's anchor phospholipid is an inositol alkylacylglycerol, and that an ester-linked substitution of the inositol underlies the resistance of E hu DAF to PI-PLC.
This study was undertaken to characterize the expression and regulation of decay-accelerating factor (DAF), a complement regulator, as a potential mediator of ovarian tissue protection from ovulatory inflammation.
Decayacceleratingfactor (DAF, CD55) expressed in human reproductive organs and gametes is thought to play a pivotal role in protection against autologous complement activation in the genital tract.
To investigate the role of DAF in reproduction, He C, et al 2000 studied decayacceleratingfactor in guinea-pig reproductive organs and analysed DAF distribution in reproductive organs using guinea-pigs that express multiple DAF isoforms.
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