Deoxycholic acid
Chemical name	(3α,5β,12α)-3,12-Dihydroxycholan-24-oic acid
Other names	Deoxycholic acid Deoxycholate
Chemical formula	C24H40O4
Molecular mass	392.58 g/mol
CAS number	[83-44-3]
Density	? g/cm3
Melting point	174 - 176 °C
SMILES	C[C@@]34[C@](CC[C@@H]4[C@@H](CCC (O)=O)C)([H])[C@]2([H])CC[C@]1([H])C [C@H](O)CC[C@@](C)1[C@] ([H])2C[C@@H]3O
Disclaimer and references

Deoxycholic acid, also known as deoxycholate, cholanoic acid, and 3α,12α-dihydroxy-5β-cholanate, is a bile acid. When pure, it comes in a white to off-white crystalline powder form. Deoxycholic acid is one of the 4 main acids produced by the liver. It is soluble in alcohol and acetic acid. Image File history File links Deoxycholic_acid. ... IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ... This article or section does not cite any references or sources. ... General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Standard atomic weight 12. ... General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ... General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ... The molecular mass (abbreviated Mr) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ... In physics, density is mass m per unit volume V. For the common case of a homogeneous substance, it is expressed as: where, in SI units: ρ (rho) is the density of the substance, measured in kg·m-3 m is the mass of the substance, measured in kg V is... The melting point of a crystalline solid is the temperature at which it changes state from solid to liquid. ... The simplified molecular input line entry specification or SMILES is a specification for unambiguously describing the structure of chemical molecules using short ASCII strings. ... Bile acids are steroid acids found predominantly in the bile of mammals. ... Acidity redirects here. ... The liver is an organ present in vertebrates and some other animals. ... Functional group of an alcohol molecule. ... Acetic acid, also known as ethanoic acid, is an organic chemical compound best recognized for giving vinegar its sour taste and pungent smell. ...

Applications

In the human body deoxycholic acid is used in the emulsification of fats for the absorption in the intestine. Outside the body it is used in experimental basis of cholagogues and is also use to prevent and dissolve gallstones. The human body is the entire physical structure of a human organism. ... An emulsion is a mixture of two immiscible substances. ... Fats consist of a wide group of compounds that are generally soluble in organic solvents and largely insoluble in water. ... In anatomy, the intestine is the segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine (or colon). ... Cholagogue is a substance which is added to the bile canaliculi in the alimentary canal during glyco-respiration. ... This article or section does not adequately cite its references or sources. ...

Sodium deoxycholate, the sodium salt of deoxycholic acid, is frequently used in mesotherapy injections, mixed with phosphatidylcholine. Mesotherapy (from Greek mesos, middle, and therapy from Greek therapeia, to treat medically) is a non-surgical cosmetic medicine treatment. ... Lecithin, also known as Phosphatidylcholine Lecithin is usually used as synonym for phosphatidylcholine, a phospholipid which is the major component of a phosphatide fraction which may be isolated from either egg yolk (in Greek lekithos - λεκιθος), or soy beans. ...

In research deoxycholic acid is used as a mild detergent for the isolation of membrane associated proteins.

Deoxycholates and bile acid derivatives in general are actively being studied as structures for incorporation in nanotechnology.^[1] They also have found application in microlithography as photoresist components. ^[2][3]

The critical micelle concentration for deoxycholic acid is approximately 0.2%. In chemistry, the critical micelle concentration (CMC) is defined as the concentration of surfactants in free solution in equilibrium with surfactants in aggregated form. ...

See also

• Ursodesoxycholic acid
• Bile acids

Ursodesoxycholic acid (also Ursodeoxycholic acid) is a component of bile acid, produced by the liver and stored in the gall bladder. ... Bile acids are steroid acids found predominantly in bile of mammals. ...

References

1. ^ Molecules, 2001, 6, 21.
2. ^ Polym. Mat. Sci. Eng., 1997, 77, 445.
3. ^ Chemistry Letters, 2000, 414.