Dermatan sulfate is a glycosaminoglycan, formerly called a mucopolysaccharide, found mostly in skin, but also in blood vessels, heart valves, tendons, and lungs. The blood vessels are part of the circulatory system and function to transport blood throughout the body. ... In anatomy, the heart valves are valves in the heart that prevent blood from flowing the wrong way. ... A tendon or sinew is a tough band of fibrous connective tissue, attached on one end to a muscle and on the other to a bone. ... The heart and lungs (from an older edition of Grays Anatomy) The lung is an organ belonging to the respiratory system and interfacing to the circulatory system of air-breathing vertebrates. ...
Dermatan sulfate accumulates abnormally in several of the mucopolysaccharidosis disorders. The mucopolysaccharidoses are inborn errors of metabolism resulting from the deficiency of specific lysosomal enzymes needed in glycosaminoglycan catabolism. ...
Dermatansulfate is a glycosaminoglycan (formerly called a mucopolysaccharide) found mostly in skin, but also in blood vessels, heart valves, tendons, and lungs.
Dermatansulfate may have roles in coagulation, cardiovascular disease, carcinogenesis, infection, wound repair, and fibrosis.
Dermatansulfate accumulates abnormally in several of the mucopolysaccharidosis disorders.
Chondroitin sulfate is a major structural component of cartilage and provides much of its resistance to compression.
Chondroitin sulfate D refers to CS predominantly sulfated at carbon 2 of the GlcA and 6 of the GalNAc sugar (chondroitin-2,6-sulfate).
Although the name "chondroitin sulfate" suggests a salt with a sulfate counter-anion, this is not the case, as sulfate is covalently attached to the sugar.
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