Destrin is a protein in microfilaments. Hugo is a masculine name. ... The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The National Center for Biotechnology Information (NCBI) is part of the US National Library of Medicine (NLM), which is a branch of the US National Institutes of Health. ... Swiss-Prot is a curated biological database of protein sequences created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute. ... Short and long arms Chromosome. ... Chromosome 20 is one of the 23 pairs of chromosomes in humans. ... This article or section should be merged with actin Microfilaments or actin filaments are made up of two twisted monomeric actin subunits. ...
Because destrin and cofilin are actin-depolymerizing proteins whose activities are possibly regulated by their phosphorylation/dephosphorylation, the two parotid proteins reported here might be involved in cortical F-actin disruption observed in parallel with exocytotic amylase secretion.
Destrin and cofilin are actin-binding proteins that induce depolymerization of F-actin(38, 39, 40).
In an attempt to obtain larger quantities of the phosphorylated destrin- and cofilin-like proteins, we incubated parotid slices with calyculin A, an inhibitor of protein phosphatases 1 and 2A(55).