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Encyclopedia > Destrin
destrin (actin depolymerizing factor)
Identifiers
Symbol DSTN
HUGO 15750
Entrez 11034
OMIM 609114
RefSeq NM_006870
UniProt P60981
Other data
Locus Chr. 20 [1]

Destrin is a protein in microfilaments. Hugo is a masculine name. ... The Entrez logo The Entrez Global Query Cross-Database Search System allows access to databases at the National Center for Biotechnology Information (NCBI) website. ... The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and - when possible - links them to the relevant genes in the human genome. ... The National Center for Biotechnology Information (NCBI) is part of the US National Library of Medicine (NLM), which is a branch of the US National Institutes of Health. ... Swiss-Prot is a curated biological database of protein sequences created in 1986 by Amos Bairoch during his PhD and developed by the Swiss Institute of Bioinformatics and the European Bioinformatics Institute. ... Short and long arms Chromosome. ... Chromosome 20 is one of the 23 pairs of chromosomes in humans. ... This article or section should be merged with actin Microfilaments or actin filaments are made up of two twisted monomeric actin subunits. ...


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  Results from FactBites:
 
Identification of Two 17-kDa Rat Parotid Gland Phosphoproteins, Subjects for Dephosphorylation upon beta-Adrenergic ... (6457 words)
Because destrin and cofilin are actin-depolymerizing proteins whose activities are possibly regulated by their phosphorylation/dephosphorylation, the two parotid proteins reported here might be involved in cortical F-actin disruption observed in parallel with exocytotic amylase secretion.
Destrin and cofilin are actin-binding proteins that induce depolymerization of F-actin(38, 39, 40).
In an attempt to obtain larger quantities of the phosphorylated destrin- and cofilin-like proteins, we incubated parotid slices with calyculin A, an inhibitor of protein phosphatases 1 and 2A(55).
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