 | | Dextropropoxyphene | | Systematic (IUPAC) name | | [(2R,3R)-4-dimethylamino- 3-methyl-1,2-diphenyl-butan-2-yl] propanoate | | Identifiers | | CAS number | 469-62-5 | | ATC code | N02AC04 | | PubChem | 10100 | | Chemical data | | Formula | C22H29NO2 | | Mol. weight | 339.471 | | Pharmacokinetic data | | Bioavailability | ? | | Metabolism | ? | | Half life | ? | | Excretion | ? | | Therapeutic considerations | | Pregnancy cat. | ? Image File history File links Dextropropoxyphene. ...
IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ...
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The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
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In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
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The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ...
Excretion is the process of eliminating waste products of metabolism and other materials that are of no use. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
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The Standard for the Uniform Scheduling of Drugs and Poisons, abbreviated SUSDP, is a document used in the regulation of drugs and poisons in Australia. ...
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| | Routes | ? | Dextropropoxyphene is an analgesic in the opioid category. It is used to treat mild to moderate pain and as an antitussive. It can be used to ease pain before, during and after an operation. It is often combined with acetaminophen in the preparation co-proxamol (Darvocet in the US and CAPADEX in AUS). In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
An analgesic (colloquially known as a painkiller) is any member of the diverse group of drugs used to relieve pain (achieve analgesia). ...
An opioid is a chemical substance that has a morphine-like action in the body. ...
A cough medicine is a drug used to treat coughing and related conditions. ...
Acetaminophen (USAN) or paracetamol (INN), is a popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ...
Dextropropoxyphene is an analgesic in the opioid category. ...
Manufactured and distributed by Eli Lilly and Company, Darvocet is a brand name for mild narcotic analgesic drug which combines Acetaminophen and Propoxy or Propoxyphene, prescribed for the relief of mild to moderate pain, with or without fever. ...
CAPADEX is prescription only medication consisting of Dextropropoxyphene Hydrochloride (32. ...
It is an optical isomer of Levopropoxyphene. The racemic mixture is called Propoxyphene. Optical isomerism is a form of isomerism (specifically stereoisomerism) whereby the different 2 isomers are the same in every way except being non-superimposable mirror images* of each other. ...
The structure of Levopropoxyphene Levopropoxyphene is an antitussive. ...
In chemistry, a racemate is a mixture of equal amounts of left- and right-handed stereoisomers of a chiral molecules. ...
Some preparations that contain dextropropoxyphene include: Distalgesic and Doloxene.
Indications
Analgesia Dextropropoxyphene, like codeine, is a "weak" opioid. Codeine is more commonly used, however some individuals (approximately 10-20% of the Caucasian population) are unable to metabolize it, due to poor functioning of the enzyme CYP2D6. It is in these people that dextropropoxyphene is particularly useful, as its metabolism does not require CYP2D6. Codeine (INN) or methylmorphine is an opiate used for its analgesic, antitussive and antidiarrheal properties. ...
It has been suggested that Caucasoid race be merged into this article or section. ...
Cytochrome P450 2D6 (abbreviated CYP2D6, EC 1. ...
Opioid withdrawal In pure form, dextropropoxyphene is commonly used to ease the withdrawal symptoms in people addicted to opioids. Being very weak in comparison to the opioids that are commonly abused, dextropropoxyphene can only act as a "partial" substitute. It does not have much effect on mental cravings; however it can be effective in alleviating physical withdrawal effects, such as muscle cramps. Withdrawal refers to the characteristic signs and symptoms that appear when a drug that causes a physical dependency is regularly used for a long time and then suddenly discontinued or decreased in dosage. ...
Dextropropoxyphene is subject to some controversy: while many physicians prescribe it for a wide range of mildly to moderately painful symptoms as well as for treatment of diarrhoea, many others refuse to prescribe it, citing its highly addictive nature and limited effectiveness. The Doctor by Samuel Luke Fildes This article is about the term physician, one type of doctor; for other uses of the word doctor see Doctor. ...
Diarrhoea is the correct way to spell the word Diarrhoea. ...
The therapeutic index of dextroproxyphene is relatively small. In the UK, dextropropoxyphene and co-proxamol are now discouraged from general use; and, since 2004, preparations containing only dextropropoxyphene have been discontinued. This has been a somewhat controversial decision, since it has caused abusers to switch to the combined product and risk acetaminophen toxicity. Australia declined to follow suit and opted to allow pure dextropropoxyphene to remain available by prescription. The therapeutic index of a medication is a comparison of the amount that causes the therapeutic effect to the amount that causes toxic effects. ...
In the United States, dextropropoxyphene HCl is available as a prescription formulation with acetaminophen in ratio anywhere from 30mg / 600mg to 60mg / 325mg, respectively. These are usually named "Darvocet." On the other hand, "Darvon" is a pure Propoxyphene preparation available in the U.S. that does not contain acetaminophen. In Australia, dextropropoxyphene is available on prescription, both as a combined product (32.5mg dextropropoxyphene per 325mg acetaminophen) known as either "Di-gesic", "Capadex", or "Paradex," and in pure form (100mg capsules) known as "Doloxene". Acetaminophen (USAN) or paracetamol (INN), is a popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ...
Adverse effects Darvocet overdose is commonly broken into two categories: liver toxicity (from acetaminophen poisoning) and dextropropoxyphene overdose. Many users experience toxic effects from the acetaminophen in pursuit of the endlessly-increasing dose required to achieve euphoria. They suffer acute liver toxicity, which causes severe stomach pain, nausea, and vomiting (all of which are increased by light or stimulation of the sense of sight). The liver is an organ in some animals, including vertebrates (and therefore humans). ...
Look up euphoria in Wiktionary, the free dictionary. ...
For other uses, see Nausea (disambiguation). ...
Vomiting (also throwing up or emesis) is the forceful expulsion of the contents of ones stomach through the mouth and sometimes the nose. ...
Dextropropoxyphene also has several other non-opioid side-effects.
Both propoxyphene and its metabolite norpropoxyphene, have local anesthetic effects at concentrations about 10 times those necessary for opioid effects. In this respect, norpropoxyphene is more potent than propoxyphene, and they are both more potent than lidocaine.[1] Anesthesia (AE), also anaesthesia (BE), is the process of blocking the perception of pain and other sensations. ...
Lidocaine (INN) (IPA: ) or lignocaine (former BAN) (IPA: ) is a common local anesthetic and antiarrhythmic drug. ...
Both propoxyphene and norpropoxyphene also have direct cardiac effects which include decreased heart rate, decreased contractility, and decreased electrical conductivity (ie, increased PR, AH, HV, and QRS intervals). Norpropoxyphene is several times more potent than propoxyphene in this activity. These effects appear to be due to their local anesthetic activity and are not reversed by naloxone.[1][2][3] The infant/neonatal rate of heartbeat is around 130-150 bpm, the toddlers about 100–130 bpm, the older childs about 90–110 bpm, and the adolescents about 80–100 bpm. ...
Contractility is one of the factors which affect myocardial performance. ...
Electrical conductivity is a measure of a materials ability to conduct an electric current. ...
Naloxone is a drug used to counter the effects of opioid overdose, for example heroin and morphine overdose. ...
Both propoxyphene and norpropoxyphene are potent blockers of cardiac membrane sodium channels and are more potent than lidocaine, quinidine, and procainamide in this respect.[4] Sodium channels are integral membrane proteins that exist in a cells plasma membrane and regulate the flow of sodium (Na+) ions into it. ...
Lidocaine (INN) (IPA: ) or lignocaine (former BAN) (IPA: ) is a common local anesthetic and antiarrhythmic drug. ...
Quinidine is a pharmaceutical agent that acts as a class I antiarrhythmic agent in the heart. ...
Procainamide (trade name Pronestyl®) is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias, classified by the Vaughan Williams classification system as class Ia. ...
They (propoxyphene and nor-propoxyphene) appear to have the characteristics of a Vaughn Williams Class IC antiarrhythmic.
Darvon, a dextropropxyphene made by Eli Lilly, which had been on the market for 25 years, came under heavy fire in 1978 by consumer groups that said it was associated with suicide. Darvon was never withdrawn from the market, but Lilly has waged a sweeping, and largely successful, campaign among doctors, pharmacists and Darvon users to defend the drug as safe when it is used in proper doses and not mixed with alcohol. One of the worlds largest corporations, Eli Lilly and Company (NYSE: LLY) is a global pharmaceutical company with headquarters in Indianapolis,Indiana, USA. A Fortune 500 corporation, the company had revenues of $12. ...
Suicide (from Latin sui caedere, to kill oneself) is the willful act of killing oneself. ...
Toxicologic Mechanism A) Excessive opioid receptor stimulation is responsible for the CNS depression, respiratory depression, miosis, and gastrointestional effects seen in propoxyphene poisoning. It may also account for mood/thought altering effects. Clinical depression is a state of sadness, melancholia or despair that has advanced to the point of being disruptive to an individuals social functioning and/or activities of daily living. ...
In medicine, hypoventilation exists when ventilation is inadequate to perform gas exchange. ...
Miosis should not be confused with meiosis, the cellular division process involved in sexual reproduction. ...
Mood may refer to: chese Grammatical mood Emotional mood This is a disambiguation page, a list of pages that otherwise might share the same title. ...
Personification of thought (Greek Εννοια) in Celsus Library in Ephesos, Turkey Thought or thinking is a mental process which allows beings to model the world, and so to deal with it effectively according to their goals, plans, ends and desires. ...
B) Local anesthetic activity appears to be responsible for the arrhythmias and cardiovascular depression seen in propoxyphene poisoning.[3] Widening of the QRS complex appears to be a result of a quinidine-like effect of propoxyphene, and sodium bicarbonate therapy appears to have a positive direct effect on the QRS dysrhythmia.[5] A cardiac arrhythmia, also called cardiac dysrhythmia, is a disturbance in the regular rhythm of the heartbeat. ...
Sodium bicarbonate is the chemical compound with the formula NaHCO3. ...
C) Seizures may result from either opioid or local anesthetic effects.[1] This article is about the medical term, epileptic seizure, as distinct from psychogenic non-epileptic seizure. ...
D) Pulmonary edema may result from direct pulmonary toxicity, neurogenic/anoxic effects, or cardiovascular depression.[3] Pulmonary edema is swelling and/or fluid accumulation in the lungs. ...
The nervous system of an animal coordinates the activity of the muscles, monitors the organs, constructs and processes input from the senses, and initiates actions. ...
Hypoxia is a pathological condition in which the body as a whole (generalised hypoxia) or region of the body (tissue hypoxia) is deprived of adequate oxygen supply. ...
Recreational use Those who take dextropropoxyphene for recreational purposes tend to take anywhere from 240 to 420 milligrams of dextropropoxyphene and, if it is not extracted, the acetaminophen that is present in the preparation. Some adverse effects of recreational dextropropoxyphene use are: a persistent dry mouth, decreased appetite, urinary retention and constipation that may lead to diverticulitis. Xerostomia is the medical term for a dry mouth due to a lack of saliva. ...
Anorexia (deriving from the Greek ÏŒÏεξη (orexe) = appetite) is the decreased sensation of appetite. ...
Urinary retention also known as ischuria is a lack of ability to urinate. ...
Constipation or irregularity, is a condition of the digestive system where a person (or animal) experiences hard feces that are difficult to eliminate; it may be extremely painful, and in severe cases (fecal impaction) lead to symptoms of bowel obstruction. ...
Diverticulitis is a common disease of the bowel, in particular the large intestine. ...
ALVIN CHONG GETS OWNED BY CHRISTOPHER PATTERSON in GEARS OF WAR! YEAH SON!
External links - Links to external chemical sources
References - ^ a b c Nickander et al., 1984
- ^ Bredgaard, Sorensen et al., 1984
- ^ a b c Strom et al., 1985b
- ^ Holland & Steinberg, 1979
- ^ Stork et al., 1995
| v • d • e Analgesics (N02A, N02B) | | Opioids: | Acetorphine, Acetyldihydrocodeine, Acetyldihydrocodeinone, Acetylmorphone, Alfentanil, Allylprodine, Alphaprodine, Anileridine, Bemidone, Benzylmorphine, beta-4-morpholinylethylmorphine, Betaprodine, Betmeprodine, Bezitramide, Buprenorphine, Butorphanol, Carfentanil, Clonitazene, Codeine, Codeine-N-Oxide, Codeinone, Cyclazocine, Cyclorphan, Desomorphine, Dextromoramide, Dextropropoxyphene, Dezocine, Diacetyldihydrocodeine, Diacetyldihydromorphine, Diethylthiambutene, Difenoxin, Dihydrocodeine, Dihydrocodeinone enol acetate, Dihydrohydroxycodeinone, Dihydrodesoxymorphine. Dihydroetorphine, Dihydroheroin, Dihydroisocodeine, Dihydromorphine, Dimethylthiambutene, Diphenoxylate, Dipipanone, Diprenorphine, Dipropanoylmorphine, Dromoran, Ethylketocyclazocine, Ethylmorphine, Etonitazene, Etorphine, Fentanyl, Diamorphine (Heroin), Hydrocodone, Hydromorphone, Isomethadone, Ketobemidone, Laudanum, Lefetamine, Levallorphan, Levo-alphacetylmethadol, Levomethorphan, Levomethadone, Levorphanol, Levopropoxyphene, Loperamide, Meptazinol, Metazocine, Methadone, Metopon, Monoacetylmorphine, Morphine-N-Oxide, Morphine, Morphinone, Morphine-6-glucuronide, MPPP, Myorphine, Nalbuphine, Nalmefene, Nalorphine, Naloxone, Naltrexone, Nicocodeine, Nicodicodeine, Nicomorphine, Norcodeine, N-allyl-normorphine, Ohmefentanyl, Omnopon, Opium, Oxycodone, Oxymorphone, Pantopon, Papaveretum, Paregoric, Pentazocine, PEPAP, Pethidine (Meperidine), Phenadoxone, Phenazocine, Phenoperidine, Pholcodeine, Piminodine, Prodine, Proheptazine, Propiram, Propoxyphene, Racemethorphan, Racemorphan, Remifentanil, Sufentanil, Tetrapon, Thebacon, Thebaine, Thiofentanil, Tilidine, Tramadol, Trimeperidine An analgesic (colloquially known as a painkiller) is any member of the diverse group of drugs used to relieve pain (achieve analgesia). ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ...
Acetyldihydrocodeine is an opiate derivative developed as a cough suppressant and analgesic. ...
Acetylmorphone (Dihydromorphinone acetate) is an opiate analogue that is an acetylated derivative of hydromorphone which was developed in the early 1900s as a potential cough suppressant and analgesic. ...
Alfentanil (Alfenta) is a parenteral short-acting opioid painkiller, used for anaesthesia in surgery. ...
Anileridine (Leritine®) is a synthetic opioid and strong analgesic medication. ...
Bezitramide (4-[4-(2-oxo-3-propanoyl-benzoimidazol-1-yl)-1-piperidyl]-2,2-diphenyl-butanenitrile MW: 492. ...
Buprenorphine, also colloquially referred to as bupe, is an opioid drug with partial agonist and antagonist actions. ...
Butorphanol (INN) is a morphinan-type synthetic opioid analgesic marketed in the US under the trade name Stadol. ...
Carfentanil, also Carfentanyl, is an analogue of the popular opioid Fentanyl, and is currently the most potent opioid known [Actually Ohmefentanil is 13,000X morphine]. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl (activity in humans starting at about 1...
Codeine (INN) or methylmorphine is an opiate used for its analgesic, antitussive and antidiarrheal properties. ...
Codeinone is a strong Opiod. ...
Cyclazocine is a mixed opiate agonist-antagonist. ...
Dextromoramide (Palfium®, Palphium®, Jetrium®, Dimorlin®) is the right-handed isomer of the moramide molecule. ...
Diacetyldihydromorphine (Paralaudin, Dihydroheroin) is a potent opiate derivative which is rarely used in some countries for the treatment of strong pain such as that caused by terminal cancer, as a more potent form of diamorphine. ...
Dihydrocodeine, also called DHC and Paracodeine and by the brand names of SS Bron, Drocode, Paracodin, Codidol, Didor Continus, Dicogesic, and DF-118 amongst others, is a semi-synthetic opioid analgesic prescribed for postoperative pain, severe dyspnea, or as an antitussive. ...
The chemical structure of dihydrocodeinone enol acetate Dihydrocodeinone Enol Acetate, or Thebacon, formerly marketed as its hydrochloride salt under the trade name Acedicon, is a semisynthetic opioid once used as an antitussive, primarily in Europe. ...
Not to be confused with oxytocin. ...
Dihydromorphine is a semi-synthetic opioid invented in Germany in the first years of the twentieth century. ...
On opiod agonist used for the treatment of diarrhea. ...
Dipipanone hydrochloride is an opioid painkiller. ...
Dipropanoylmorphine is the 3,6-dipropanoyl ester of morphine. ...
A potent, easily synthesized opioid often used as a substitute for morphine or a stronger opioid (such as fentanyl) when used in illegal drugs. ...
Ethylmorphine is a drug in the class of both opiates (representing a minor synthetic change from morphine) and opioids (being effective in the CNSs opioid reception system) . Its effects in humans mainly stem from its metabolic conversion to morphine. ...
Etonitazene, (2-(p-Ethoxybenzyl)-1-diethylaminoethyl-5-nitrobenzimidazole), is a schedule I opiate. ...
Etorphine (Immobilon® or M99) is a synthetic cousin of morphine and 1000 - 80,000 times more powerful. ...
To meet Wikipedias quality standards, this article or section may require cleanup. ...
Heroin, also known as diamorphine (BAN) or diacetylmorphine (INN), is a semi-synthetic opioid. ...
It has been suggested that Vicodin be merged into this article or section. ...
Hydromorphone is a drug used to relieve moderate to severe pain. ...
Ketobemidone structure Ketobemidone is a powerful opioid analgesic. ...
Laudanum is an opium tincture, sometimes sweetened with sugar and also called wine of opium. ...
Lefetamine is a psychoactive drug which has effects similar to both morphine and methylphenidate. ...
Levo-alpha-acetyl-methadol (LAAM for short) is a synthetic opioid similar in structure to methadone. ...
Levomethorphan is an optical isomer of dextromethorphan. ...
Levorphanol is an opioid medication used to treat severe pain. ...
The structure of Levopropoxyphene Levopropoxyphene is an antitussive. ...
Loperamide, usually as hydrochloride, is a drug effective against diarrhea resulting from gastroenteritis or inflammatory bowel disease. ...
Methadone is a synthetic opioid, used medically as an analgesic and in the treatment of narcotic addiction. ...
6-monoacetylmorphine (6-MAM) is one of 2 active metabolites of heroin (diacetylmorphine), the other being the much less active 3-monoacetylmorphine (3-MAM). ...
Morphine (INN) (IPA: ) is an highly potent opiate analgesic drug and is the principal active agent in opium and the prototypical opiate. ...
Morphinone is a very strong Opiod. ...
Morphine-6-glucuronide (M6G) is of more than simply academic interest, since it is the major active metabolite of morphine, and as such is the molecule responsible for much of the pain-relieving effects of morphine (and heroin and codeine). ...
MPPP (1-methyl 4-phenyl 4-propionoxypiperidine) is an opioid analgesic drug. ...
Nalbuphine (nalbuphine hydrochloride) is a synthetic opioid used commercially as an analgesic under a variety of trade names, including Nubain. ...
Nalmefene (Revex) is an opioid receptor antagonist used primarily in the management of alcohol dependence, and also has been investigated for the treatment of other addictions such as pathological gambling and addiction to shopping. ...
Naloxone is a drug used to counter the effects of opioid overdose, for example heroin and morphine overdose. ...
Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. ...
Nicocodeine (Lyopect) is an opiate derivative developed as a cough suppressant and analgesic. ...
Nicodicodeine is an opiate derivative developed as a cough suppressant and analgesic. ...
Nicomorphine (Vilan) is the 3,6-dinicotinate ester of morphine. ...
// Ohmefentanyl (OMF) is related to a fentanyl analogue called 3-methyl-fentanyl (3-MF)[1],[2]. OMF is more sophisticated than 3-MF though since it also has a β-hydroxy group situated on the phenethyl tail. ...
Opium, or opïum is a narcotic analgesic drug which is obtained from the unripe seed pods of the opium poppy (Papaver somniferum L. or the synonym paeoniflorum). ...
Not to be confused with oxytocin. ...
Oxymorphone (Numorphan) is a powerful semi-synthetic narcotic analgesic that is derived from morphine, and is approximately 6-8 times more potent. ...
Pantopon is a preparation of opiates made up of all of the alkaloids present in opium in their natural proportions as hydrochloride salts . ...
Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. ...
Paregoric, also known as Camphorated Opium Tincture, is a medicine known for its antidiarrhoeal and systemic properties. ...
Pentazocine is a synthetically-prepared narcotic drug used to treat mild to moderate pain. ...
Pethidine (INN) or meperidine (USAN) (also referred to as: isonipecaine; lidol; operidine; pethanol; piridosal; Algil®; Alodan®; Centralgin®; Demerol®; Dispadol®; Dolantin®; Dolestine®; Dolosal®; Dolsin®; Mefedina®) is a fast-acting opioid analgesic drug. ...
Phenoperidine is an opiod general anesthetic. ...
Pholcodeine is an opioid used primarily as an antitussant (to treat cough) with little abuse potential. ...
Dextropropoxyphene is an analgesic in the opioid category that is used to treat severe pain and severe coughs. ...
Racemethorphan is a racemic mixture of the stereoisomers of methorphan , namely dextromethorphan , which is the active ingredient in DM cough syrups , and the lesser known levomethorphan which is described as a controlled substance in The Merck Index - likely because it has more potential for abuse than its dextro enantiomer . ...
Remifentanil is a potent ultra short-acting synthetic opioid analgesic drug. ...
Sufentanil is a drug that belongs to the class of drugs known as the opioid analgesic drugs. ...
The chemical structure of dihydrocodeinone enol acetate Dihydrocodeinone Enol Acetate, or Thebacon, formerly marketed as its hydrochloride salt under the trade name Acedicon, is a semisynthetic opioid once used as an antitussive, primarily in Europe. ...
A minor constituent of opium, thebaine or paramorphine (C19H21NO3) is chemically similar to both morphine and codeine, but produces stimulatory rather than depressant effects. ...
Tramadol (INN) (IPA: ) is an atypical opioid which is a centrally acting analgesic, used for treating moderate to severe pain. ...
| | Salicylic acid and derivatives: | Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide -- See also: NSAIDs Salicylic acid is the chemical compound with the formula C6H4(OH)CO2H, where the OH group is adjacent to the carboxylic acid group. ...
Aspirin or acetylsalicylic acid (acetosal) is a drug in the family of salicylates, often used as an analgesic (against minor pains and aches), antipyretic (against fever), and anti-inflammatory. ...
Diflunisal is a generic NSAID (Non Steroidal Anti Inflammatory Drug). ...
Ethenzamide is a common analgesic and antiinflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains. ...
| | Pyrazolones: | Aminophenazone, Metamizole, Phenazone Pyrazole Phenazone Ampyrone Phenylbutazone Pyrazolone, a five-membered-ring lactam, is a derivative of pyrazole that has an additional keto (=O) group. ...
Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. ...
Metamizole sodium ( [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl) methylamino] methanesulfonate ) is a non-steroidal anti-inflammatory drug ( NSAID ), commonly used in the past as a powerful painkiller and fever reducer. ...
Phenazone is an analgesics. ...
| | Anilides: | Paracetamol (acetaminophen), Phenacetin Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2 (or C6H7N). ...
Paracetamol (INN) (IPA: ) or acetaminophen (USAN), is a common analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. ...
Phenacetin, introduced in 1887, is used principally as an analgesic. ...
| | Others: | Ziconotide, Tetrahydrocannabinol, Ibuprofen, Ketoprofen, Mefenamic Acid, Naproxen, Diclofenac, Flurbiprofen, Diflunisal, Fenoprofen, Indomethacin, Ketorolac, Meclofenamate, Meloxicam, Piroxicam, Tolmetin Ziconotide is a non-opioid, non local anesthetic used for the amelioration of chronic pain. ...
Tetrahydrocannabinol, also known as THC, Δ9-THC, Δ9-tetrahydrocannabinol (delta-9-tetrahydrocannabinol), Δ¹-tetrahydrocannabinol (using an older numbering scheme), or dronabinol, is the main psychoactive substance found in the Cannabis plant. ...
Ibuprofen (INN) (IPA: ) is a non-steroidal anti-inflammatory drug (NSAID) widely marketed under various trademarks including Herron Blue, Act-3, Advil, Brufen, Motrin, Nuprin, Dorival and Nurofen. ...
Ketoprofen, (RS)2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects. ...
This article needs to be cleaned up to conform to a higher standard of quality. ...
Naproxen (trade names: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury, menstrual cramps, tendinitis, bursitis, and the...
Diclofenac (marketed as Voltaren®, Voltarol®, Diclon®, Dicloflex® Difen and Cataflam®) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and an analgesic reducing pain in conditions such as in arthritis or acute injury. ...
Flurbiprofen is an NSAID (non-steroidal anti-inflammatory drug) used to treat the inflammation and pain of arthritis. ...
Diflunisal is a generic NSAID (Non Steroidal Anti Inflammatory Drug). ...
Indomethacin (USAN) or indometacin (INN) is a non-steroidal anti-inflammatory drug commonly used to reduce fever, pain, stiffness, and swelling. ...
Ketorolac or ketorolac tromethamine (marketed as Toradol® - generics have been approved) is a non-steroidal anti-inflammatory drug (NSAID) in the family of propionic acids, often used as an analgesic, antipyretic (fever reducer), and anti-inflammatory. ...
Meloxicam is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ...
Piroxicam (US trade name Feldene) is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component. ...
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