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Diabetic retinopathy is retinopathy (damage to the retina) caused by complications of diabetes mellitus, which could eventually lead to blindness. It is an ocular manifestation of systemic disease which affects up to 80% of all diabetics who have had diabetes for 15 years or more[citation needed]. Despite these intimidating statistics, research indicates that at least 90% of these new cases could be reduced if there was proper and vigilant treatment and monitoring of the eyes[citation needed]. The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...
The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). ...
// H00-H59 - Diseases of the eye and adnexa (H00-H06) Disorders of eyelid, lacrimal system and orbit (H00) Hordeolum and chalazion (H000) Hordeolum and other deep inflammation of eyelid (H001) Chalazion (H01) Other inflammation of eyelid (H010) Blepharitis (H011) Noninfectious dermatoses of eyelid (H02) Other disorders of eyelid (H020) Entropion...
// E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other...
// E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other...
// E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other...
// E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other...
// E00-E35 - Endocrine diseases (E00-E07) Disorders of thyroid gland (E00) Congenital iodine-deficiency syndrome (E01) Iodine-deficiency-related thyroid disorders and allied conditions (E02) Subclinical iodine-deficiency hypothyroidism (E03) Other hypothyroidism (E030) Congenital hypothyroidism with diffuse goitre (E031) Congenital hypothyroidism without goitre (E032) Hypothyroidism due to medicaments and other...
The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify diseases and a wide variety of signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or disease. ...
The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. ...
The Disease Bold textDatabase is a free website that provides information about the relationships between medical conditions, symptoms, and medications. ...
MedlinePlus (medlineplus. ...
eMedicine is an online clinical medical knowledge base that was founded in 1996. ...
Retinopathy is a general term that refers to some form of non-inflammatory damage to the retina of the eye. ...
Human eye cross-sectional view. ...
For the disease characterized by excretion of large amounts of very dilute urine, see diabetes insipidus. ...
Blindness is the condition of lacking visual perception due to physiological or psychological factors. ...
Many systemic diseases have symptoms or manifestations related to the eye or visual system. ...
The same view with diabetic retinopathy. human eyesight two children and ball normal vision Copyright: public domain, US gov. ...
human eyesight two children and ball normal vision Copyright: public domain, US gov. ...
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for medical research. ...
The National Eye Institute (NEI) is one of the US National Institutes of Health that was established in 1968. ...
human eyesight two children and ball with diabetic retinopathy Copyright: public domain, US gov. ...
human eyesight two children and ball with diabetic retinopathy Copyright: public domain, US gov. ...
Signs and symptoms Diabetic retinopathy often has no early warning signs. Even macular edema, which may cause vision loss more rapidly, may not have any warning signs for some time. In general, however, a person with macular edema is likely to have blurred vision, making it hard to do things like read and drive. In some cases, the vision will get better or worse during the day. Macular edema occurs when fluid and protein deposits collect on or under the macula, causing it to thicken and swell. ...
As new blood vessels form at the back of the eye as a part of proliferative diabetic retinopathy (PDR), they can bleed (haemorrhage) and blur vision. The first time this happens, it may not be very severe. In most cases, it will leave just a few specks of blood, or spots, floating in a person's visual field, though the spots often go away after a few hours. Hemorrhage (alternate spelling is Haemorrhage) is the medical term meaning bleeding. ...
Human blood smear: a - erythrocytes; b - neutrophil; c - eosinophil; d - lymphocyte. ...
These spots are often followed within a few days or weeks by a much greater leakage of blood, which blurs vision. In extreme cases, a person will only be able to tell light from dark in that eye. It may take the blood anywhere from a few days to months or even years to clear from the inside of the eye, and in some cases the blood will not clear. These types of large hemorrhages tend to happen more than once, often during sleep. A child sleeping Sleep is the state of natural rest observed in humans and throughout the animal kingdom, including in all mammals and birds, and in many reptiles, amphibians and fish. ...
On fundoscopic exam, a doctor will see cotton wool spots, flame hemorrhages, and dot-blot hemorrhages. The ophthalmoscope is an instrument used to examine the eye. ...
Cotton wool spots are an abnormal finding on fundoscopic exam of the retina. ...
Diabetes mellitus
| | Types of Diabetes | Diabetes mellitus type 1 Diabetes mellitus type 2 Gestational diabetes Pre-diabetes: Impaired fasting glycaemia Impaired glucose tolerance For the disease characterized by excretion of large amounts of very dilute urine, see diabetes insipidus. ...
Diabetes mellitus type 1 (Type 1 diabetes, Type I diabetes, T1D, IDDM) is a form of diabetes mellitus. ...
See diabetes mellitus for further general information on diabetes. ...
Gestational diabetes is a form of diabetes found in pregnant women. ...
Impaired fasting glycaemia (IFG) is a pre-diabetic state of dysglycemia, associated with insulin resistance and increased risk cardiovascular pathology, although of lesser risk than Impaired glucose tolerance (IGT). ...
Impaired Glucose Tolerance (IGT) is a pre-diabetic state of dysglycemia, that is associated with insulin resistance and increased risk of cardiovascular pathology. ...
| | Disease Management | Diabetes management: •Diabetic diet •Anti-diabetic drugs •Conventional insulinotherapy •Intensive insulinotherapy | | Other Concerns | | Cardiovascular disease Diabetic comas: •Diabetic hypoglycemia •Diabetic ketoacidosis •Nonketotic hyperosmolar This article is about the management of diabetes mellitus. ...
The diet recommended for people who suffer from diabetes mellitus is one that is high in dietary fibre, especially soluble fibre, but low in fat (especially saturated fat) and sugar. ...
An anti-diabetic drug or oral hypoglycemic agent is used to treat diabetes mellitus. ...
Conventional insulinotherapy is a therapeutic regimen for diabetes mellitus treatment. ...
Intensive insulinotherapy or flexible insulin therapy is a therapeutic regimen for diabetes mellitus treatment. ...
Cardiovascular disease refers to the class of diseases that involve the heart and/or blood vessels (arteries and veins). ...
Diabetic coma is a medical emergency in which a person with diabetes mellitus is comatose (unconscious) because of one of three acute complications of diabetes: Severe diabetic hypoglycemia Advanced diabetic ketoacidosis advanced enough to result in unconsciousness from a combination of severe hyperglycemia, dehydration and shock, and exhaustion Hyperosmolar nonketotic...
Diabetic hypoglycemia describes low blood glucose (hypoglycemia) occurring in a person with diabetes mellitus. ...
Diabetic ketoacidosis (DKA) is a life-threatening complication in patients with untreated diabetes mellitus (chronic high blood sugar or hyperglycemia). ...
Nonketotic hyperosmolar coma is a type of diabetic coma associated with a high mortality seen in diabetes mellitus type 2. ...
Diabetic myonecrosis Diabetic nephropathy Diabetic neuropathy Diabetic retinopathy Please wikify (format) this article or section as suggested in the Guide to layout and the Manual of Style. ...
Photomicrography of nodular glomerulosclerosis in Kimmelstein-Wilson syndrome. ...
Diabetic neuropathies are neuropathic disorders that are associated with diabetes mellitus. ...
Diabetes and pregnancy For women with diabetes mellitus, pregnancy can present some particular challenges for both mother and child. ...
| | Blood tests | Fructosamine Glucose tolerance test Glycosylated hemoglobin | Fructosamine, also known as Glycated Serum Protein (GSP) or Glycated Albumin, is used primarily to identify the plasma glucose concentration over time and so assess diabetic control . ...
A glucose tolerance test in medical practice is the administration of glucose to determine how quickly it is cleared from the blood. ...
Glycosylated (or glycated) hemoglobin (hemoglobin A1c, Hb1c , HbA1c or HgA1c) is a form of hemoglobin used primarily to identify the plasma glucose concentration over time. ...
Pathogenesis Small blood vessels – such as those in the eye – are especially vulnerable to poor blood glucose control. An overaccumulation of glucose and/or fructose damages the tiny blood vessels in the retina. During the initial stage, called nonproliferative diabetic retinopathy (NPDR), most people do not notice any changes in their vision. f you all The blood vessels are part of the circulatory system and function to transport blood throughout the body. ...
In medicine, blood sugar is glucose in the blood. ...
Glucose (Glc), a monosaccharide (or simple sugar), is the most important carbohydrate in biology. ...
Fructose (or levulose) is a simple sugar (monosaccharide) found in many foods and is one of the three most important blood sugars along with glucose and galactose. ...
Some people develop a condition called macular edema. It occurs when the damaged blood vessels leak fluid and lipids onto the macula, the part of the retina that lets us see detail. The fluid makes the macula swell, which blurs vision. Macular edema occurs when fluid and protein deposits collect on or under the macula, causing it to thicken and swell. ...
A polyunsaturated triglyceride. ...
Human eye cross-sectional view. ...
As the disease progresses, severe nonproliferative diabetic retinopathy enters an advanced, or proliferative, stage. The lack of oxygen in the retina causes fragile, new, blood vessels to grow along the retina and in the clear, gel-like vitreous that fills the inside of the eye. Without timely treatment, these new blood vessels can bleed, cloud vision, and destroy the retina. Fibrovascular proliferation can also cause tractional retinal detachment. The new blood vessels can also grow into the angle of the anterior chamber of the eye and cause Neovascular Glaucoma. Nonproliferative diabetic retinopathy shows up as cotton wool spots, or microvascular abnormalities or as superficial retinal hemorrhages. Even so, the advanced proliferative diabetic retinopathy (PDR) can remain asymptomatic for a very long time, and so should be monitored closely with regular checkups. General Name, Symbol, Number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, Period, Block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ...
Vitreous refers to a material in a glassy state. ...
Strictly, Cotton wool is the silky fibers from cotton plants in their raw state. ...
In medicine, a disease is asymptomatic when it is at a stage where the patient does not experience symptoms. ...
Risk factors All people with diabetes mellitus are at risk – those with Type I diabetes (juvenile onset) and those with Type II diabetes (adult onset). The longer a person has diabetes, the higher the risk of developing some ocular problem. Between 40 to 45 percent of Americans diagnosed with diabetes have some stage of diabetic retinopathy. [1] After 20 years of diabetes, nearly all patients with type 1 diabetes and >60% of patients with type 2 diabetes have some degree of retinopathy.[2] During pregnancy, diabetic retinopathy may also be a problem for women with diabetes. It is recommended that all pregnant women with diabetes have dilated eye examinations each trimester to protect their vision. A pregnant woman near the end of her term Pregnancy is the carrying of one or more embryos or fetuses by female mammals, including humans, inside their bodies. ...
Traditional Snellen chart used for visual acuity testing. ...
The human gestation period of approximately 40 weeks between the time of the last menstrual cycle and delivery is traditionally divided into three periods of three months, or trimesters. ...
Diagnosis Diabetic retinopathy is detected during an eye examination that includes: Traditional Snellen chart used for visual acuity testing. ...
- Visual acuity test: This test uses an eye chart to measure how well a person sees at various distances (i.e., visual acuity).
- Pupil dilation: The eye care professional places drops into the eye to widen the pupil. This allows him or her to see more of the retina and look for signs of diabetic retinopathy. After the examination, close-up vision may remain blurred for several hours.
- Ophthalmoscopy: This is an examination of the retina in which the eye care professional: (1) looks through a device with a special magnifying lens that provides a narrow view of the retina, or (2) wearing a headset with a bright light, looks through a special magnifying glass and gains a wide view of the retina. Note that hand-held ophthalmoscopy is insufficient to rule out significant and treatable diabetic retinopathy.
- Tonometry: A standard test that determines the fluid pressure (intraocular pressure) inside the eye. Elevated pressure is a possible sign of glaucoma, another common eye problem in people with diabetes.
- Digital Retinal Screening Programs: Systematic programs for the early detection of eye disease including diabetic retinopathy are becoming more common, such as in the UK, where all people with diabetes mellitus are offered retinal screening at least annually. This involves digital image capture and transmission of the images to a digital reading center for evaluation and treatment referral. See Vanderbilt Ophthalmic Imaging Center [1] and the UK National Screening Committee [2]
- Slit Lamp Biomicroscopy Retinal Screening Programs: Systematic programs for the early detection of diabetic retinopathy using slit-lamp biomicroscopy. These exist either as a standalone scheme or as part of the Digital program (above) where the digital photograph was considered to lack enough clarity for detection and/or diagnosis of any retinal abnormality.
The eye care professional will look at the retina for early signs of the disease, such as: (1) leaking blood vessels, (2) retinal swelling, such as macular edema, (3) pale, fatty deposits on the retina (exudates) – signs of leaking blood vessels, (4) damaged nerve tissue (neuropathy), and (5) any changes in the blood vessels. Traditional Snellen chart. ...
Traditional Snellen chart used for visual acuity testing. ...
The human eye The pupil is the central transparent area (showing as black). ...
In medicine, a sign is a feature of disease as detected by the doctor. ...
In medicine the ophthalmoscope was invented by Hermann von Helmholtz and is an instrument that is used to look into the human eye. ...
Intraocular pressure is the fluid pressure inside the eye. ...
For the disease characterized by excretion of large amounts of very dilute urine, see diabetes insipidus. ...
Nerves (yellow) Nerves redirects here. ...
Neuropathy is usually short for peripheral neuropathy, meaning a disease of the peripheral nervous system. ...
Should the doctor suspect macular edema, he or she may perform a test called fluorescein angiography. In this test, a special dye is injected into the arm. Pictures are then taken as the dye passes through the blood vessels in the retina. This test allows the doctor to find the leaking blood vessels. Macular edema occurs when fluid and protein deposits collect on or under the macula, causing it to thicken and swell. ...
Fluorescein angiography, or fluorescent angiography, is a technique for examining the circulation of the retina. ...
Look up dye in Wiktionary, the free dictionary. ...
Look up ARM in Wiktionary, the free dictionary. ...
For images in Wikipedia, see Wikipedia:Images. ...
Management There are three major treatments for diabetic retinopathy, which are very effective in reducing vision loss from this disease. In fact, even people with advanced retinopathy have a 90 percent chance of keeping their vision when they get treatment before the retina is severely damaged. Still, the best way of addressing diabetic retinopathy is to monitor it vigilantly and ensure that it does not happen in the first place by careful blood glucose control and limitation of dietary fructose. Fructose (or levulose) is a simple sugar (monosaccharide) found in many foods and is one of the three most important blood sugars along with glucose and galactose. ...
These three treatments are laser surgery, injection of triamcinolone into the eye and vitrectomy. It is important to note that although these treatments are very successful, they do not cure diabetic retinopathy. Caution should be exercised in treatment with laser surgery since it causes a loss of retinal tissue. It is often more prudent to inject triamcinolone. In some patients it results in a marked increase of vision, especially if there is an edema of the macula. Vitreous humour is the clear gel that fills the eyeball, lying between the lens and the retina in the eye. ...
Avoiding tobacco use and correction of associated hypertension are important therapeutic measures in the management of diabetic retinopathy. [3]
Laser surgery A type of laser surgery called panretinal photocoagulation, or PRP, is used to treat severe macular edema and proliferative retinopathy. The goal is to create 1 000 - 2 000 burns in the retina with the hope of reducing the retina's oxygen demand, and hence the possibility of ischemia. In treating advanced diabetic retinopathy, the burns are used to destroy the abnormal blood vessels that form at the back of the eye. Before the surgery, the ophthalmologist dilates the pupil and applies anesthetic drops to numb the eye. In some cases, the doctor also may numb the area behind the eye to prevent any discomfort. The lights in the office are also dimmed to aid in dilating the pupil. The patient sits facing the laser machine while the doctor holds a special lens to the eye. During the procedure, the patient may see flashes of light. These flashes may eventually create an uncomfortable stinging sensation for the patient. After the laser treatment, patients should be advised not to drive for a few hours while the pupils are still dilated. Vision may remain a little blurry for the rest of the day, though there should not be much pain in the eye. Ophthalmology is the branch of medicine which deals with the diseases of the eye and their treatment. ...
Anesthesia (AE), also anaesthesia (BE), is the process of blocking the perception of pain and other sensations. ...
This article does not cite any references or sources. ...
Scatter laser treatment Rather than focus the light on a single spot, the eye care professional may make hundreds of small laser burns away from the center of the retina, a procedure called scatter laser treatment or panretinal photocoagulation. The treatment shrinks the abnormal blood vessels. Patients may lose some of their peripheral vision after this surgery, but the procedure saves the rest of the patient's sight. Laser surgery may also slightly reduce colour and night vision. A person with proliferative retinopathy will always be at risk for new bleeding as well as glaucoma, a complication from the new blood vessels. This means that multiple treatments may be required to protect vision.
Vitrectomy Instead of laser surgery, some people need an eye operation called a vitrectomy to restore vision. A vitrectomy is performed when there is a lot of blood in the vitreous. It involves removing the cloudy vitreous and replacing it with a saline solution made up of salt and water. Because the vitreous is mostly water, there should be no change between the saline solution and the normal vitreous. Vitreous humour is the clear gel that fills the eyeball, lying between the lens and the retina in the eye. ...
Vitreous humour is the clear aqueous solution that fills the space between the lens and the retina of the vertebrate eyeball. ...
For other uses, see Salt (disambiguation). ...
Impact from a water drop causes an upward rebound jet surrounded by circular capillary waves. ...
Studies show that people who have a vitrectomy soon after a large hemorrhage are more likely to protect their vision than someone who waits to have the operation. Early vitrectomy is especially effective in people with insulin-dependent diabetes, who may be at greater risk of blindness from a hemorrhage into the eye. Vitrectomy is often done under local anesthesia. The doctor makes a tiny incision in the sclera, or white of the eye. Next, a small instrument is placed into the eye to remove the vitreous and insert the saline solution into the eye. Local anesthesia is any technique to render part of the body insensitive to pain without affecting consciousness. ...
Schematic diagram of the human eye. ...
Patients may be able to return home soon after the vitrectomy, or may be asked to stay in the hospital overnight. After the operation, the eye will be red and sensitive, and patients usually need to wear an eyepatch for a few days or weeks to protect the eye. Medicated eye drops are also prescribed to protect against infection. For the record label, see Hospital Records. ...
Red is any of a number of similar colors evoked by light consisting predominantly of the longest wavelengths of light discernible by the human eye, in the wavelength range of roughly 625â750 nm. ...
An infection is the detrimental colonization of a host organism by a foreign species. ...
References - ^ NIHSeniorHealth: Diabetic Retinopathy - Causes and Risk Factors. Diabetic Retinopathy. NIHSenior Health (2005).
- ^ Screening for Diabetic Retinopathy. Diabetic Retinopathy. American Diabetes Association (2002).
- ^ Diabetes Ocular complications. Chronic Complications of Diabetes. Armenian Medical Network (2006).
- The original text of this document was taken from the public domain resource document "Facts About Diabetic Retinopathy", at http://www.nei.nih.gov/health/diabetic/retinopathy.asp See the copyright statement at http://www.nei.nih.gov/order/index.htm, which says "Our publications are not copyrighted and may be reproduced without permission. However, we do ask that credit be given to the National Eye Institute, National Institutes of Health."
- Basic ophthalmology for medical students and primary care residents, 7th edition
- Kawasaki T, Ogata N, Akanuma H, Sakai T, Watanabe H, Ichiyanagi K, Yamanouchi T. Postprandial plasma fructose level is associated with retinopathy in patients with type 2 diabetes. Metabolism 2004;53:583-8. Fulltext. PMID 15131761.
- Eye Care for Diabetics
Shortcut: WP:PD There are many resources available on the net that are in the public domain, and therefore freely usable without restrictions for Wikipedia content. ...
External Links - National Diabetes Information Clearinghouse
- Lions Eye Institute, Perth, Australia
- Educational website on Diabetic Retinopathy
| Endocrine pathology: endocrine diseases (E00-35, 240-259) | | Thyroid | Hypothyroidism (Iodine deficiency, Cretinism, Congenital hypothyroidism, Goitre) - Hyperthyroidism (Graves disease, Toxic multinodular goitre, Teratoma with thyroid tissue or Struma ovarii) - Thyroiditis (De Quervain's thyroiditis, Hashimoto's thyroiditis) | | Pancreas | Diabetes mellitus (type 1, type 2, coma, angiopathy, ketoacidosis, nephropathy, neuropathy, retinopathy) - Hypoglycemia - Hyperinsulinism - Zollinger-Ellison syndrome | | Parathyroid | Hypoparathyroidism (Pseudohypoparathyroidism) - Hyperparathyroidism (Primary, Secondary, Tertiary) | | Pituitary | hyperfunction (Acromegaly, Hyperprolactinaemia, Syndrome of inappropriate antidiuretic hormone) - Hypopituitarism (Sheehan's syndrome, Kallmann syndrome, Simmonds' disease, Growth hormone deficiency) - Diabetes insipidus - Hypothalamic-pituitary dysfunction | | Adrenal | Cushing's syndrome (Nelson's syndrome, Pseudo-Cushing's syndrome) - Congenital adrenal hyperplasia (due to 21-hydroxylase deficiency) - Hyperaldosteronism (Conn syndrome, Bartter syndrome) - Adrenal insufficiency (Addison's disease) - Hypoaldosteronism | | Gonads | Polycystic ovary syndrome - 5-alpha-reductase deficiency - Hypogonadism - Delayed puberty - Precocious puberty | | Other | Autoimmune polyendocrine syndrome - Carcinoid syndrome - Laron syndrome - Multiple endocrine neoplasia - Psychogenic dwarfism - Androgen insensitivity syndrome - Progeria | | Pathology of the eye (primarily H00-H59, 360-379) | | Eyelid, lacrimal system and orbit | Stye - Chalazion - Blepharitis - Entropion - Ectropion - Lagophthalmos - Blepharochalasis - Ptosis - Xanthelasma - Trichiasis - Dacryoadenitis - Epiphora - Exophthalmos - Enophthalmos | | Conjunctiva | Conjunctivitis - Pterygium - Pinguecula - Subconjunctival hemorrhage | | Sclera and cornea | Scleritis - Keratitis - Corneal ulcer - Snow blindness - Thygeson's superficial punctate keratopathy - Fuchs' dystrophy - Keratoconus - Keratoconjunctivitis sicca - Arc eye - Keratoconjunctivitis - Corneal neovascularization - Kayser-Fleischer ring - Arcus senilis | | Iris and ciliary body | Iritis - Uveitis - Iridocyclitis - Hyphema - Persistent pupillary membrane | | Lens | Cataract - Aphakia | | Choroid and retina | Retinal detachment - Retinoschisis - Retinopathy (Hypertensive retinopathy, Diabetic retinopathy, Retinopathy of prematurity) - Macular degeneration - Retinitis pigmentosa - Macular edema - Epiretinal membrane - Macular pucker | | Optic nerve and visual pathways | Optic neuritis - Papilledema - Optic atrophy | | Ocular muscles, binocular movement, accommodation and refraction | Paralytic strabismus: Ophthalmoparesis - Progressive external ophthalmoplegia - Palsy (III, IV, VI) - Kearns-Sayre syndrome Other strabismus: Esotropia/Exotropia - Hypertropia - Heterophoria (Esophoria, Exophoria) - Brown's syndrome - Duane syndrome Endocrinology is a branch of medicine dealing with disorders of the endocrine system and its specific secretions called hormones. ...
Pathology (from Greek pathos, feeling, pain, suffering; and logos, study of; see also -ology) is the study of the processes underlying disease and other forms of illness, harmful abnormality, or dysfunction. ...
Among the hundreds of endocrine diseases (or endocrinological diseases) are: Adrenal disorders: Adrenal insufficiency Addisons disease Congenital adrenal hyperplasia (adrenogenital syndrome) Mineralocorticoid deficiency Conns syndrome Cushings syndrome Pheochromocytoma Adrenocortical carcinoma Glucose homeostasis disorders: Diabetes mellitus Hypoglycemia Idiopathic hypoglycemia Insulinoma Metabolic bone disease: Osteoporosis Osteitis deformans (Pagets...
This article or section does not cite its references or sources. ...
This article does not cite any references or sources. ...
Cretinism (most likely from the Latin ChristiÄnum, Christian) is a condition of severely stunted physical and mental growth due to untreated congenital deficiency of thyroid hormones (hypothyroidism). ...
Congenital hypothyroidism (CHT) is a condition of thyroid hormone deficiency present at birth. ...
A goitre (or goiter) (Latin struma), also called a bronchocele, is a swelling in the neck (just below Adams apple or larynx) due to an enlarged thyroid gland. ...
Hyperthyroidism (or overactive thyroid gland) is the clinical syndrome caused by an excess of circulating free thyroxine (T4) or free triiodothyronine (T3), or both. ...
Graves disease is a thyroid disorder characterized by goiter, exophthalmos, orange-peel skin, and hyperthyroidism. ...
Toxic multinodular goitre (also known as toxic nodular goitre, toxic nodular struma) is a form of hyperthyroidism - where there is excess production of thyroid hormones. ...
A teratoma is a type of neoplasm (specifically, a tumor). ...
A teratoma is a type of tumor that derives from pluripotent germ cells. ...
de Quervains thyroiditis, is also known as subacute granulomatous thyroiditis or subacute thyroiditis; usually occurs in women between 30 and 50 years of age. ...
This disease was discovered by Mr. ...
The pancreas is an organ in the digestive and endocrine system (of vertebrates[2]). It is both exocrine (secreting pancreatic juice containing digestive enzymes) and endocrine (producing several important hormones, including insulin, glucagon, and somatostatin). ...
For the disease characterized by excretion of large amounts of very dilute urine, see diabetes insipidus. ...
Diabetes mellitus type 1 (Type 1 diabetes, Type I diabetes, T1D, IDDM) is a form of diabetes mellitus. ...
See diabetes mellitus for further general information on diabetes. ...
Diabetic coma is a medical emergency in which a person with diabetes mellitus is comatose (unconscious) because of one of three acute complications of diabetes: Severe diabetic hypoglycemia Advanced diabetic ketoacidosis advanced enough to result in unconsciousness from a combination of severe hyperglycemia, dehydration and shock, and exhaustion Hyperosmolar nonketotic...
Angiopathy is a disease of the blood vessels (arteries, veins, and capillaries) that occurs when someone has diabetes for a long time. ...
Diabetic ketoacidosis (DKA) is a life-threatening complication in patients with untreated diabetes mellitus (chronic high blood sugar or hyperglycemia). ...
Photomicrography of nodular glomerulosclerosis in Kimmelstein-Wilson syndrome. ...
Diabetic neuropathies are neuropathic disorders that are associated with diabetes mellitus. ...
Hypoglycemia (hypoglycæmia in the UK) is a medical term referring to a pathologic state produced by a lower than normal level of sugar (glucose) in the blood. ...
Hyperinsulism or hyperinsulinemia is a condition in which the bodys cells do not respond properly to insulin, the hormone that functions to control blood sugar levels. ...
Zollinger-Ellison syndrome is a disorder where increased levels of the hormone gastrin are produced, causing the stomach to produce excess hydrochloric acid. ...
The four human parathyroid glands are adjacent to the thyroid. ...
In medicine (endocrinology), hypoparathyroidism is decreased function of the parathyroid glands, leading to decreased levels of parathyroid hormone (PTH). ...
Pseudohypoparathyroidism is a condition that mimics hypoparathyroidism, but is due to a resistance to parathyroid hormone, rather than a lack of the hormone (akin to the distinction between Type 1 diabetes and Type 2 diabetes. ...
Hyperparathyroidism is overactivity of the parathyroid glands resulting in excess production of parathyroid hormone (PTH). ...
Primary hyperparathyroidism causes hypercalcemia (elevated blood calcium levels) through the excessive secretion of parathyroid hormone (PTH), usually by an adenoma (benign tumors) of the parathyroid glands. ...
Secondary hyperparathyroidism refers to the excessive secretion of parathyroid hormone (PTH) by the parathyroid glands in response to hypocalcemia (low blood calcium levels) and associated hypertrophy of the glands. ...
Tertiary hyperparathyroidism is a state of excessive secretion of parathyroid hormone (PTH) after a long period of secondary hyperparathyroidism and resulting in hypercalcemia. ...
The pituitary gland, or hypophysis, is an endocrine gland about the size of a pea that sits in a small, bony cavity (pituitary fossa) covered by a dural fold (sellar diaphragm) at the base of the brain. ...
Acromegaly (from Greek akros high and megas large - extremities enlargement) is a hormonal disorder that results when the pituitary gland produces excess growth hormone (hGH). ...
Prolactin is a hormone secreted by lactotropes in the adenohypophysis (anterior pituitary gland) which is made up of 199 amino acids with a molecular weight of about 23,000 daltons. ...
The syndrome of inappropriate antidiuretic hormone (SIADH) is a condition commonly found in the hospital population, especially in patients being hospitalized for central nervous system (CNS) injury. ...
Hypopituitarism is a medical term describing deficiency (hypo) of one or more hormones of the pituitary gland. ...
Sheehan syndrome, also known as postpartum hypopituitarism or postpartum pituitary necrosis, is hypopituitarism (decreased functioning of the pituitary gland), caused by necrosis due to blood loss and hypovolemic shock during and after childbirth. ...
Kallmann syndrome is an example of hypogonadism (decreased functioning of the sex hormone-producing glands) caused by a deficiency of gonadotropin-releasing hormone (GnRH), which is created by the hypothalamus. ...
Simmonds disease (also Simmonds syndrome) refers to panhypopituitarism caused by the destruction of the pituitary gland due to infiltrative processes (e. ...
Growth hormone deficiency is the medical condition of inadequate production of growth hormone (GH) and its effects on children and adults. ...
Diabetes insipidus (DI) is a disease characterized by excretion of large amounts of severely diluted urine, which cannot be reduced when fluid intake is reduced. ...
Hypothalamic-pituitary dysfunction is a term to describe a nonorganic relative inactivity of the gonadotropin-releasing hormone (GnRH) system of the hypothalamus and its dependent pituitary gonadotrophs that normally produce follicle stimulating hormone, FSH, and luteinizing hormone, LH. The condition occurs during the reproductive years and leads to hypogonadotropic hypogonadism. ...
In mammals, the adrenal gland (also known as suprarenal glands) are the triangle-shaped endocrine glands that sit atop the kidneys; their name indicates that position (ad, near or at + renes, kidneys). They are chiefly responsible for regulating the stress response through the synthesis of corticosteroids and catecholamines, including cortisol...
Wikipedia does not have an article with this exact name. ...
Pseudo-Cushings syndrome is a medical condition in which patients display the signs, symptoms, and abnormal hormone levels seen in Cushings syndrome. ...
Congenital adrenal hyperplasia (CAH) refers to any of several autosomal recessive diseases resulting from defects in steps of the synthesis of cortisol from cholesterol by the adrenal glands. ...
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency, in all its forms, accounts for about 95% of diagnosed cases of congenital adrenal hyperplasia, and CAH in most contexts refers to 21-hydroxylase deficiency. ...
Conns syndrome is overproduction of the mineralocorticoid hormone aldosterone by the adrenal glands. ...
Bartter syndrome is a rare genetic disease characterized by low potassium levels (hypokalemia), decreased acidity of blood (alkalosis), and normal to low blood pressure. ...
In medicine, adrenal insufficiency (or hypocortisolism) is the inability of the adrenal gland to produce adequate amounts of cortisol in response to stress. ...
Addisons disease (also known as chronic adrenal insufficiency, or hypocortisolism) is a rare endocrine disorder in which the body produces insufficient amounts of adrenal steroid hormones (glucocorticoids and often mineralocorticoids). ...
In medicine (endocrinology), hypoaldosteronism refers to decreased levels of the hormone aldosterone. ...
The gonad is the organ that makes gametes. ...
Polycystic ovary syndrome (PCOS, also known clinically as Stein-Leventhal syndrome), is an endocrine disorder that affects 4%â7% of women. ...
It has been suggested that this article or section be merged with Guevedoche. ...
Hypogonadism is a medical term for a defect of the reproductive system which results in lack of function of the gonads (ovaries or testes). ...
Puberty is described as delayed when a boy or girl has passed the usual age of onset of puberty with no physical or hormonal signs that it is beginning. ...
Precocious puberty means early puberty. ...
In medicine, autoimmune polyendocrine syndromes are a heterogenous group of rare diseases characterised by autoimmune activity against more than one endocrine organs, although non-endocrine organs can be affected. ...
Carcinoid syndrome refers to the array of symptoms that occur secondary to carcinoid tumors. ...
Laron syndrome is a disorder characterized by an insensitivity to growth hormone, caused by a variant of the growth hormone receptor. ...
Multiple endocrine neoplasia (MEN) (or multiple endocrine adenomas, or multiple endocrine adenomatosis -- MEA) consists of three syndromes featuring tumors of endocrine glands, each with its own characteristic pattern. ...
Psychogenic dwarfism, Psychosocial dwarfism or Stress dwarfism is a growth disorder that is observed between the ages of 2 and 15, caused by extreme emotional deprivation or stress. ...
Androgen insensitivity syndrome (AIS, or Androgen resistance syndrome) is a set of disorders of sexual differentiation that results from mutations of the gene encoding the androgen receptor. ...
The term Progeria narrowly refers to Hutchinson-Gilford Progeria syndrome, but the term is also used more generally to describe any of the so-called accelerated aging diseases. The word progeria is derived from the Greek for prematurely old. Because the accelerated aging diseases display different aspects of aging, but...
Pathology (from Greek pathos, feeling, pain, suffering; and logos, study of; see also -ology) is the study of the processes underlying disease and other forms of illness, harmful abnormality, or dysfunction. ...
// A human eye. ...
An eyelid is a thin fold of skin and muscle that covers and protects an eye. ...
Tears are a liquid produced by the bodys process of lacrimation to clean and lubricate the eyes. ...
In anatomy, the orbit is the cavity or socket of the skull in which the eye and its appendages are situated. ...
A stye or hordeolum {IPA|/ËhoɹËdi. ...
A chalazion, also known as a Meibomian gland lipogranuloma, is a cyst in the eyelid that is caused by inflammation of the meibomian gland, usually on the upper eyelid. ...
Blepharitis is inflammation of the eyelids. ...
Entropion is a medical condition in which the eyelids fold inward. ...
Ectropion is a condition of loose eyelids. ...
Lagophthalmos describes difficulty in complete closure of the eyelid over the eyeball. ...
Blepharochalasis is an inflammation of the eyelid that is characterized by exacerbations and remissions of eyelid edema, which results in a stretching and subsequent atrophy of the eyelid tissue. ...
In ophthalmology, ptosis is an abnormally low position (drooping) of the upper eyelid. ...
Xanthelasma (or xanthelasma palpebrarum) are sharply demarcated yellowish collections of cholesterol underneath the skin, usually around the eyes. ...
Trichiasis is a medical term for ingrown eyelashes. ...
Dacryoadenitis is inflammation of the lacrimal glands (the tear-producing glands). ...
Epiphora is excessive tear production, usually a result from an irritation of the eye. ...
Exophthalmos (or proptosis) is a bulging of the eye anteriorly out of the orbit. ...
Enophthalmos is recession of the eyeball within the orbit. ...
The conjunctiva is a membrane that covers the sclera (white part of the eye) and lines the inside of the eyelids. ...
A pterygium, meaning wing, is a benign growth of the conjunctiva. ...
A Pinguecula is a type of conjunctival degeneration in the eye. ...
A subconjunctival hemorrhage is a common and relatively minor post-LASIK complication. ...
Schematic diagram of the human eye. ...
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber, providing most of an eyes optical power [1]. Together with the lens, the cornea refracts light and, as a result, helps the eye to focus. ...
Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as the sclera. ...
A corneal ulcer is an inflammatory condition of the cornea involving loss of its outer layer. ...
For other meanings see Snowblind. ...
Thygesons superficial punctate keratopathy (TSPK) is a disease of the eyes. ...
Fuchs dystrophy is a slowly progressing corneal disease that usually affects both eyes and is slightly more common in women than in men. ...
Keratoconus (from Greek: kerato- horn, cornea; and konos cone), is a degenerative non-inflammatory disorder of the eye in which structural changes within the cornea cause it to thin and change to a more conical shape than its normal gradual curve. ...
Keratoconjunctivitis sicca (KCS), also called keratitis sicca,[1] sicca syndrome,[1] xerophthalmia,[1] dry eye syndrome (DES),[1] or simply dry eyes,[1] is an eye disease caused by decreased tear production or increased tear film evaporation commonly found in humans and some animals[2]. Keratoconjunctivitis sicca is Latin and...
Arc eye, also known as arc flash, welders flash, corneal flash burns, or flash burns, is a painful ocular condition sometimes experienced by welders who have failed to use adequate eye protection. ...
Keratoconjunctivitis sicca or KCS is an eye disease caused by decreased tear production or increased tear film evaporation commonly found in people and small animals. ...
Corneal neovascularization is the excessive ingrowth of blood vessels from the limbal vascular plexus into the cornea. ...
Kayser-Fleischer rings are pigmented rings in the peripheral cornea, resulting from copper deposition in Descemets membrane. ...
Arcus senilis (or Arcus senilis corneae. ...
The human iris The iris is the green/grey/brown area. ...
Schematic diagram of the human eye The ciliary body is the part of the eye containing the ciliary muscle and ciliary processes. ...
Iritis is a form of anterior uveitis and refers to the inflammation of the iris of the eye. ...
Uveitis specifically refers to inflammation of the middle layer of the eye, termed the uvea but in common usage may refer to any inflammatory process involving the interior of the eye. ...
Iridocyclitis, also known as anterior uveitis, is a condition in which the uvea of the eye suffers inflammation. ...
Caused by a blunt blow to the eye. ...
Persistent pupillary membrane (PPM) is a condition of the eye involving remnants of a fetal membrane that persist as strands of tissue crossing the pupil. ...
Light from a single point of a distant object and light from a single point of a near object being brought to a focus by changing the curvature of the lens. ...
Human eye cross-sectional view, showing position of human lens. ...
Aphakia is the absence of the lens of the eye, due to surgical removal, perforating wound or ulcer, or congenital anomaly; causes a loss of accommodation, hyperopia, and a deep anterior chamber. ...
The choroid, also known as the choroidea or choroid coat, is the vascular layer of the eye lying between the retina and the sclera. ...
Human eye cross-sectional view. ...
Retinal detachment is a disorder of the eye in which the retina peels away from its underlying layer of support tissue. ...
Retinoschisis is an uncommon eye disease characterized by the abnormal splitting of the retinas sensory layers, usually in the outer plexiform layer, with resulting loss of visual function [1]. The retina, which consists of multiple layers of interconnected nerve and pigment cells, separates into separate layers resulting in a...
Retinopathy is a general term that refers to some form of non-inflammatory damage to the retina of the eye. ...
Hypertension, or high blood pressure that does not respond to treatment, has several ocular manifestations. ...
Retinopathy of prematurity (ROP), previously known as retrolental fibroplasia (RLF), is a disease of the eye that affects prematurely born babies. ...
Listen to this article · (info) · play in browser This audio file was created from an article revision dated 2005-07-19, and may not reflect subsequent edits to the article. ...
Normal vision. ...
Macular edema occurs when fluid and protein deposits collect on or under the macula, causing it to thicken and swell. ...
Human eye cross-sectional view. ...
Human eye cross-sectional view. ...
This article is about the anatomical structure. ...
The visual system is the part of the nervous system which allows organisms to see. ...
Optic [[neuritis](or retrobulbar neuritis) is the inflammation of the optic nerve that may cause a complete or partial loss of vision. ...
Papilledema is optic disc swelling that is caused by increased intracranial pressure. ...
Optic atrophy is a pathological term and somewhat misleading. ...
MRI scan showing lateral and medial rectus muscles. ...
Binocular vision is vision in which both eyes are used together. ...
Light from a single point of a distant object and light from a single point of a near object being brought to a focus by changing the curvature of the lens. ...
The straw seems to be broken, due to refraction of light as it emerges into the air. ...
Ophthalmoparesis is a physical finding in certain neurologic illnesses. ...
Progressive external ophthalmoplegia is a disorder of the mitochondria. ...
Damage to the oculomotor nerve, termed oculomotor nerve palsy is known by the down n out symptoms. ...
Fourth nerve palsy is a condition present at birth characterized by a vertical misalignment of the eyes due to a weakness or paralysis of the superior oblique muscle. ...
Sixth nerve palsy, or abducens nerve palsy, is a disorder associated with dysfunction of cranial nerve VI (the abducens nerve) which is responsible for contracting the lateral rectus muscle to abduct (i. ...
Kearns-Sayre syndrome (abbreviated KSS) is a disease caused by a 5,000 base deletion in the mitochondrial DNA. As such, it is a rare genetic disease in that it can be heteroplasmic, that is, more than one genome can be in a cell at any given time. ...
For the protein Strabismus, see Strabismus (protein) Strabismus, also known as heterotropia, squint, crossed eye, cockeyed, wandering eye,weak eye or wall eyed, is a condition in which the eyes are not properly aligned with each other. ...
Person exhibiting esotropia of the right eye Esotropia is a form of strabismus where one or both of the eyes turn inward. ...
Exotropia is a form of strabismus where the eyes are deviated outward. ...
Hypertropia is a condition of misalignment of the eyes (strabismus), whereby the visual axis of one eye is higher than the fellow fixating eye. ...
Heterophoria is a type of eye condition where the motion of the eyes is not parallel to each other. ...
Esophoria is characterised by inward deviation of the eye usually due to extra-ocular muscle imbalance. ...
This article or section does not cite any references or sources. ...
Browns syndrome is due to fibrous adhesions in the upper medial quadrant of the orbit. ...
An individual diagnosed with Duane syndrome in the left eye. ...
Other binocular: Conjugate gaze palsy - Convergence insufficiency - Internuclear ophthalmoplegia - One and a half syndrome Conjugate gaze palsy refers to an inability of both eyes to move in the same direction at the same time. ...
Convergence insufficiency is a sensory and neuromuscular anomaly of the binocular vision system, characterized by an inability to converge the eyes or sustain convergence. ...
Internuclear ophthalmoplegia is a physical finding, or sign, that is a particular form of [[[ophthalmoparesis]]. It can affect either the right or left eye. ...
Schematic representation of most common extra-ocular movement abnormality in one and a half syndrome. ...
Refractive error: Hyperopia/Myopia - Astigmatism - Anisometropia/Aniseikonia - Presbyopia | | Visual disturbances and blindness | Amblyopia - Leber's congenital amaurosis - Subjective (Asthenopia, Hemeralopia, Photophobia, Scintillating scotoma) - Diplopia - Scotoma - Anopsia (Binasal hemianopsia, Bitemporal hemianopsia, Homonymous hemianopsia, Quadrantanopia) - Color blindness (Achromatopsia) - Nyctalopia - Blindness/Low vision | | Pupil | Anisocoria - Argyll Robertson pupil - Marcus Gunn pupil/Marcus Gunn phenomenon - Adie syndrome | | Infectious diseases | Trachoma - Onchocerciasis | | Other | Nystagmus - Mydriasis - Glaucoma - Floater - Leber's hereditary optic neuropathy - Red eye - Keratomycosis - Xerophthalmia - Aniridia | |