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Encyclopedia > Dibenzepin
Dibenzepin chemical structure
Dibenzepin
Systematic (IUPAC) name
?
Identifiers
CAS number 4498-32-2
ATC code N06AA08
PubChem 9419
Chemical data
Formula C18H21N3O
Mol. weight 295.379
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.

? IUPAC nomenclature is a systematic way of naming organic chemical compounds. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... A section of the Anatomical Therapeutic Chemical Classification System. ... PubChem is a database of chemical molecules . ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Santorio Santorio (1561-1636) in his steelyard balance, from Ars de statica medecina, first published 1614 Metabolism (from μεταβολισμος (metabolismos)) is the biochemical modification of chemical compounds in living organisms anggjgjhnd cell (b). ... The liver is an organ in vertebrates including humans. ... The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ... Excretion is the biological process by which an organism chemically separates waste products from its body. ... Kidneys viewed from behind with spine removed The kidneys are bean-shaped excretory organs in vertebrates. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother. ...

Legal status

? The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...

Routes Oral

Dibenzepin (Noveril®) is a muscarinic antagonist. It is indicated for use as an antidepressant. In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... Muscarinic receptors are those membrane-bound acetylcholine receptors that are more sensitive to muscarine than to nicotine. ... An antidepressant is a medication designed to treat or alleviate the symptoms of clinical depression. ...



  Antidepressants (ATC N06A)  v·d·e 
Monoamine oxidase inhibitors (MAOI): {Harmaline} {Nialamide} {Selegiline} {Isocarboxazid} {Iproniazid} {Iproclozide} {Phenelzine} {Toloxatone} {Tranylcypromine}

Reversible Inhibitor of Monoamine oxidase A (RIMA): {Brofaromine} {Moclobemide} An antidepressant is a medication designed to treat or alleviate the symptoms of clinical depression. ... A section of the Anatomical Therapeutic Chemical Classification System. ... Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. ... Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. ... Harmala, also known at various times as Telepathine and Banisterine, is a blanket term for a group of naturally occurring beta-carbolines including harmine, harmaline, and others. ... Nialamide (Espril®, Niamid®, Niaquitil®, Nuredal®, Nyazin®, and Psicodisten®) was one of the first MAOI (monoamine oxidase inhibitor) antidepressants. ... Selegiline (l-deprenyl, Eldepryl® or Anipryl® [veterinary]) is a drug used for the treatment of early-stage Parkinsons disease and senile dementia. ... Isocarboxazid is a nonselective hydrazine-derived monoamine oxidase inhibitor used in treatment resistant depression. ... Iproniazid is a monamine oxidase inhibitor (MAOI) that was developed as the first anti-depressant (Also first psychiatric drug). ... Phenelzine (brand name Nardil) is an antidepressant drug that belongs to the monoamine oxidase inhibitor (MAOI) class of drugs. ... Tranylcypromine is an antidepressant drug. ... These drugs, a subset of monoamine oxidase inhibitors (MAOIs), inhibit only isoenzyme A and are reversible. ... These drugs, a subset of monoamine oxidase inhibitors (MAOIs), inhibit only isoenzyme A and are reversible. ... Brofarmine is a psychiatric drug primarily used to treat depression and anxiety. ... Moclobemide (sold as Aurorix®, Manerix®) is a psychiatric drug primarily used to treat depression and social anxiety. ...


Dopamine Reuptake Inhibitor (DARI): {Amineptine} {Methylphenidate} {Phenmetrazine} {Vanoxerine} {Nomifensine} This article or section does not cite its references or sources. ... Amineptine is an atypical tricyclic antidepressant that selectively inhibits the reuptake of dopamine and to a lesser extent norepinephrine, thus exerting a powerful and fast-acting antidepressant effect. ... Methylphenidate (MPH) is an amphetamine-like prescription stimulant commonly used to treat Attention Deficit Hyperactivity Disorder (ADHD) in children and adults. ... Phenmetrazine is an amphetamine-like drug. ... Vanoxerine, also known as GBR-12909, is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. ... Nomifensine is a dopamine reuptake inhibitor that increases the amount of synaptic dopamine available to receptors by blocking dopamines re-uptake transporter. ...


Norepinephrine-dopamine reuptake inhibitors: {Bupropion} A Norepinephrine-dopamine reuptake inhibitor is a class of drugs that is both: Dopamine reuptake inhibitor Norepinephrine reuptake inhibitor An example is Bupropion. ... Bupropion (amfebutamone) (brand names Wellbutrin and Zyban) is an antidepressant of the aminoketone class, chemically unrelated to tricyclics or selective serotonin reuptake inhibitors (SSRIs). ...


Norepinephrine Reuptake Inhibitor (NRI) or (NARI): {Atomoxetine} {Reboxetine} {Viloxazine} {Maprotiline} Norepinephrine reuptake inhibitors (NRIs) are compounds that increase amounts of the neurotransmitter norepinephrine in the brain by inhibiting its reuptake at synapses. ... Atomoxetine is a drug used in the treatment of attention-deficit hyperactivity disorder (ADHD). ... Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesilate ( methanesulfonate) salt is sold under tradenames including Edronax®, Norebox®, Prolift®, Solvex® or Vestra®. Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine. ... Viloxazine is a bicyclic antidepressants[2] that inhibits the reuptake of serotonin, and to a lesser extent, dopamine and norepinephrine. ... To meet Wikipedias quality standards, this article may require cleanup. ...


Serotonin-Norepinephrine Reuptake Inhibitor (SNRI): {Desipramine} {Duloxetine} {Milnacipran} {Venlafaxine} Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant used in the treatment of clinical depression and other affective disorders. ... Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. ... Duloxetine hydrochloride (brand names: Cymbalta/Yentreve) is a medically used drug that primarily targets major depressive disorders (MDD), pain related to diabetic peripheral neuropathy and stress urinary incontinence (SUI). ... Milnacipran is an antidepressant of the serotonin-norepinephrine reuptake inhibitor class. ... Venlafaxine hydrochloride is a prescription antidepressant first introduced by Wyeth in 1993. ...


Selective Serotonin Reuptake Inhibitor (SSRI): {Alaproclate} {Etoperidone} {Citalopram} {Escitalopram} {Fluoxetine} {Fluvoxamine} {Paroxetine} {Sertraline} {Zimelidine} Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants for treating depression, anxiety disorders and some personality disorders. ... Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants for treating depression, anxiety disorders and some personality disorders. ... Alaproclate is an antidepressant that increases serotonin levels by inhibiting the uptake of 5-HT. Today, its primarily used to stagment the cravings for cocaine. ... Etoperidone is a 5-HT agonist used primarily in the 1970s to impede the effects of LSD. ... Citalopram or nitalapram is an antidepressant drug used to treat the depression associated with mood disorders. ... Escitalopram is a medication developed by the Danish pharmaceutical company Lundbeck, that acts as a selective serotonin reuptake inhibitor or SSRI. It is typically used as an antidepressant to treat depression associated with mood disorders although also may be used in the treatment of body dysmorphic disorder and anxiety. ... Fluoxetine hydrochloride is an antidepressant drug used medically in the treatment of depression, obsessive-compulsive disorder, bulimia nervosa, premenstrual dysphoric disorder and panic disorder. ... Fluvoxamine maleate (sold under the brand-names Luvox® and Faverin®) is a selective serotonin reuptake inhibitor. ... To meet Wikipedias quality standards, this article or section may require cleanup. ... Sertraline hydrochloride (Zoloft®, Sertralin®, Lustral®, Apo-Sertral®, Asentra®, Gladem®, Serlift®, Stimuloton®, Xydep®, Serlain®, Concorz®) is an orally administered antidepressant of the selective serotonin reuptake inhibitor (SSRI) type. ... // General Remars and History Zimelidine is a pyridylallylamine and has a structure different from other antidepressants. ...


Selective Serotonin Reuptake Enhancer (SSRE): {Tianeptine} Tianeptine (INN) (Stablon®, Coaxil®, Tatinol®), is structurally similar to the tricyclic antidepressants. ... Tianeptine (INN) (Stablon®, Coaxil®, Tatinol®), is structurally similar to the tricyclic antidepressants. ... Tianeptine (INN) (Stablon®, Coaxil®, Tatinol®), is an SSRE, or Selective Serotonin Reuptake Enhancer, structurally similar to the tricyclic antidepressants. ...


Tricyclic antidepressants (TCA): {Amitriptyline} {Butriptyline} {Clomipramine} {Desipramine} {Dibenzepin} {Dothiepin} {Doxepin} {Imipramine} {Lofepramine} {Nortriptyline} {Protriptyline} {Trimipramine} {Melitracen} {Iprindole} {Opipramol} {Amoxapine} Chemical structure of the tricyclic antidepressant amitriptyline Tricyclic antidepressants are a class of antidepressant drugs first used in the 1950s. ... Chemical structure of the tricyclic antidepressant amitriptyline Tricyclic antidepressants are a class of antidepressant drugs first used in the 1950s. ... Amitriptyline hydrochloride is an antidepressant drug from the tricyclic antidepressant group, which is sold under the trade names Elavil®, Tryptanol® or Endep®. It is a white, odorless, crystalline compound which is freely soluble in water. ... Butriptyline (Dl-10,11-Dihydro-N,N,beta-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine) is a tricyclic antidepressant with sedative properties and uses similar to that of amitriptyline. ... Clomipramine (brand-name Anafranil®) is a tricyclic antidepressant. ... Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. ... Dosulepin hydrochloride (sometimes known outside the USA as dothiepin hydrochloride) is an antidepressant of the tricyclic family. ... Doxepin is a tricyclic antidepressant, known under many brand-names such as Aponal®, the original preparation by Boehringer-Ingelheim, now part of the Roche group; Adapine®, Sinquan® and Sinequan® (Pfizer Inc. ... Imipramine (tradenames: Janimine®, Tofranil®) is an antidepressant medication belonging to a class called tricyclic antidepressants of the dibenzazepine group, mainly used in the treatment of clinical depression and enuresis. ... Nortriptyline is a tricyclic antidepressant marketed under the tradenames Aventyl® and Pamelor®. It is used to treat depression. ... Trimipramine is an tricyclic antidepressant with sedative and anxiolytic properties. ... Amoxapine (Asendin®; Asendis®; Defanyl®; Demolox®; Moxadil®) is a tricyclic antidepressant of the dibenzoxazepine class. ...


Tetracyclic antidepressants: {Maprotiline} {Mianserin} {Trazodone} {Nefazodone} The structure of the tetracyclic antidepressant mirtazapine A tetracyclic antidepressant is an antidepressant drug from the tetracyclic drug group. ... To meet Wikipedias quality standards, this article may require cleanup. ... Mianserin is a tetracyclic antidepressant that has an antihistaminic and hypnosedative, but almost no anticholinergic effect. ... Trazodone (Desyrel®, Trittico®, Thombran®, Trialodine®) is a psychoactive compound with sedative, anxiolytic, and antidepressant properties. ... // Introduction Serzone (nefazodone) Serzone ( Nefazodone HCl ) is an antidepressant drug formerly marketed by Bristol-Myers Squibb. ...


Noradrenergic and Specific Serotonergic Antidepressant (NaSSA): {Mirtazapine} Noradrenergic and specific serotonergic antidepressants (abbreviated: NaSSAs) are a relatively new class of antidepressants. ... Noradrenergic and specific serotonergic antidepressants (abbreviated: NaSSAs) are a relatively new class of antidepressants. ... Mirtazapine is a prescription antidepressant introduced by Organon International in 1996. ...


  Results from FactBites:
 
Dibenzepin overdose causing pulmonary edema -- Wirtheim and Bloch 30 (7): 789 -- The Annals of Pharmacotherapy (224 words)
OBJECTIVE: To report a case of pulmonary edema due to dibenzepin overdose.
CASE SUMMARY: A 39-year-old woman was hospitalized 24 hours after she ingested eight tablets of dibenzepin hydrochloride delayed-release 240 mg/tablet (approximately 35 mg/kg body weight).
Forty-five hours after ingestion of the dibenzepin she developed pulmonary edema and was treated with furosemide, morphine, and mechanical ventilation through an endotracheal tube for 48 hours.
  More results at FactBites »


 
 

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