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| | Dipipanone | | Systematic (IUPAC) name | | 4,4-Diphenyl-6-(1-piperidinyl)-3-heptanone | | Identifiers | | CAS number | 467-83-4 | | ATC code | ? | | PubChem | ? | | Chemical data | | Formula | C24H31NO | | Mol. mass | 349.52 | | Pharmacokinetic data | | Bioavailability | ? | | Metabolism | ? | | Half life | ? | | Excretion | ? | | Therapeutic considerations | | Pregnancy cat. | ? Image File history File links No higher resolution available. ...
IUPAC nomenclature is a system of naming chemical compounds and of describing the science of chemistry in general. ...
CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences, mixtures and alloys. ...
The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
PubChem is a database of chemical molecules. ...
A chemical formula is a concise way of expressing information about the atoms that constitute a particular chemical compound. ...
For other uses, see Carbon (disambiguation). ...
General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ...
General Name, symbol, number nitrogen, N, 7 Chemical series nonmetals Group, period, block 15, 2, p Appearance colorless gas Standard atomic weight 14. ...
General Name, symbol, number oxygen, O, 8 Chemical series nonmetals, chalcogens Group, period, block 16, 2, p Appearance colorless (gas) very pale blue (liquid) Standard atomic weight 15. ...
The molecular mass (abbreviated Mr) of a substance, formerly also called molecular weight and abbreviated as MW, is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
Drug metabolism is the metabolism of drugs, their biochemical modification or degradation, usually through specialized enzymatic systems. ...
It has been suggested that Effective half-life be merged into this article or section. ...
The kidneys are important excretory organs in vertebrates. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. ...
| | Legal status | | | Routes | ? | Dipipanone hydrochloride is an opioid painkiller. In combination with cyclizine hydrochloride, it is marketed as Diconal, indicated for relief of moderate to severe pain. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...
In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body. ...
An opioid is a chemical substance that has a morphine-like action in the body. ...
Cyclizine is an antihistamine drug used to treat nausea, vomiting and dizziness associated with motion sickness, vertigo and post-operative following administration of general anaesthesia and opioids. ...
Chemically, dipipanone belongs to the class of opiates called the 3-diphenyl heptanones. It closely resembles methadone, the only structural difference being the N,N-dimethyl moiety of methadone being replaced with a piperidine ring. It's usage is now officially discouraged because of the abuse risk. The combination with cyclizine lends a very strong rush if the drug is injected. During the late 1970s to early 1980s in the UK, a whole spate of deaths were blamed on this preparation. As supplies became unavailable, opiate users would mix crushed methadone tablets with crushed Valoid (a cyclizine containing antihistamine) tablets in an attempt to replecate the affect of dipipanone. R-phrases , , Related Compounds Related compounds pyridine pyrrolidine piperazine Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references Piperidine is an organic compound with the molecular formula C5H11N. It is a heterocyclic amine with a six-membered...
See P. A. J. Janssen, Synthetic Analgesics. Part 1. Diphenylpropylamines, Pergamon Press, NY. for details on the synthesis of methadone and its cogeners before 1960. The general procedure for synthesis is illustrated by nucleophillic attack of diphenylacetonitrile on 2-chloro--1-dimethylaminoethane. The resulting aminonitrile is then converted to the ethyl ketone with ethyl magnesium bromide by way of the kitimine which is hydrolized by cold aqueous acid (Casey & Parfitt, Opioid Analgesics, Plenum Press, NY, london).
External links
| Opioids | | Opiate derivatives | 6-methyldihydromorphine • Acetyldihydrocodeine • Acetyldihydrocodeinone • Acetylmorphone • Benzylmorphine • β-4-morpholinylethylmorphine • Codeine • Codeine-N-Oxide • Codeinone • Desomorphine • Diacetyldihydromorphine • Dihydrocodeine • Dihydrocodeinone enol acetate • Dihydrohydroxycodeinone • Dihydrodesoxymorphine • Dihydroheroin • Dihydroisocodeine • Dihydromorphine • Dipropanoylmorphine • Ethylmorphine • Heroin (Diamorphine) • Heterocodeine • Hydrocodone • Hydromorphinol • Hydromorphone • Laudanum • Methyldesorphine • Methyldihydromorphine • Metopon • Monoacetylmorphine • Morphine-N-Oxide • Morphine • Morphinone • Morphine-6-glucuronide • Myorphine • Nalbuphine • Nalmefene • Nalorphine • Naloxone • Naltrexone • Nicocodeine • Nicodicodeine • Nicomorphine • Norcodeine • Normorphine • Omnopon • Opium • Oripavine • Oxycodone • Oxymorphone • Pantopon • Papaveretum • Paregoric • Pholcodeine • Pseudomorphine • Tetrapon • Thebacon • Thebaine An opioid is a chemical substance that has a morphine-like action in the body. ...
Scoring the poppy pod. ...
Acetyldihydrocodeine is an opiate derivative developed as a cough suppressant and analgesic. ...
This article or section does not adequately cite its references or sources. ...
Acetylmorphone (Dihydromorphinone acetate) is an opiate analogue that is an acetylated derivative of hydromorphone which was developed in the early 1900s as a potential cough suppressant and analgesic. ...
This article needs additional references or sources to facilitate its verification. ...
Codeine (INN) or methylmorphine is an opiate used for its analgesic, antitussive and antidiarrheal properties. ...
Codeinone is a strong Opiod. ...
Diacetyldihydromorphine (Paralaudin, Dihydroheroin) is a potent opiate derivative which is rarely used in some countries for the treatment of strong pain such as that caused by terminal cancer, as a more potent form of diamorphine. ...
Dihydrocodeine, also called DHC and Paracodeine and by the brand names of Synalgos DC, Panlor DC, Panlor SS, SS Bron, Drocode, Paracodin, Codidol, Didor Continus, Dicogesic, and DF-118 amongst others, is a semi-synthetic opioid analgesic prescribed for postoperative pain, severe dyspnea, or as an antitussive. ...
The chemical structure of dihydrocodeinone enol acetate Dihydrocodeinone Enol Acetate, or Thebacon, formerly marketed as its hydrochloride salt under the trade name Acedicon, is a semisynthetic opioid once used as an antitussive, primarily in Europe. ...
Not to be confused with oxytocin. ...
Diacetyldihydromorphine (Paralaudin, Dihydroheroin) is a potent opiate derivative developed in Germany in 1929 which is rarely used in some countries for the treatment of strong pain such as that caused by terminal cancer, as a more potent form of diamorphine. ...
Dihydromorphine is a semi-synthetic opioid invented in Germany in the first years of the twentieth century. ...
Dipropanoylmorphine is the 3,6-dipropanoyl ester of morphine, CAS number 10589-79-4. ...
Ethylmorphine is a drug in the class of both opiates (representing a minor synthetic change from morphine) and opioids (being effective in the CNSs opioid reception system) . Its effects in humans mainly stem from its metabolic conversion to morphine. ...
For other uses, see Heroin (disambiguation). ...
Heterocodeine (6-methylmorphine) is an opiate derivative, the 6-methyl ether of morphine, and a structural isomer of codeine. ...
Hydrocodone or dihydrocodeinone (marketed as Vicodin, Anexsia, Dicodid, Hycodan (or generically Hydromet), Hycomine, Lorcet, Lortab, Norco, Novahistex, Hydroco, Tussionex, Vicoprofen, Xodol) is a semi-synthetic opioid derived from two of the naturally occurring opiates, codeine and thebaine. ...
Hydromorphone is a drug developed in Germany in the 1920s and introduced to the mass market beginning in 1926. ...
Laudanum is an opium tincture, sometimes sweetened with sugar and also called wine of opium. ...
Metopon (5-methylhydromorphone hydrochloride) is an opiate analogue that is a methylated derivative of hydromorphone which was invented in 1948 as an analgesic. ...
6-monoacetylmorphine (6-MAM) is one of 2 active metabolites of heroin (diacetylmorphine), the other being the much less active 3-monoacetylmorphine (3-MAM). ...
Morphine (INN) (IPA: ) is a highly potent opiate analgesic drug and is the principal active agent in opium and the prototypical opiate. ...
Morphinone is a very strong Opiod. ...
Morphine-6-glucuronide (M6G) is of more than simply academic interest, since it is the major active metabolite of morphine, and as such is the molecule responsible for much of the pain-relieving effects of morphine (and heroin and codeine). ...
Nalbuphine (nalbuphine hydrochloride) is a synthetic opioid used commercially as an analgesic under a variety of trade names, including Nubain. ...
Nalmefene (Revex) is an opioid receptor antagonist used primarily in the management of alcohol dependence, and also has been investigated for the treatment of other addictions such as pathological gambling and addiction to shopping. ...
Nalorphine (INN, also known as N-allyl-normorphine) is a narcotic antagonist. ...
Naloxone is a drug used to counter the effects of opioid overdose, for example heroin and morphine overdose. ...
Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. ...
Nicocodeine (Lyopect) is an opiate derivative developed as a cough suppressant and analgesic. ...
Nicodicodeine is an opiate derivative developed as a cough suppressant and analgesic. ...
Nicomorphine (Vilan) is the 3,6-dinicotinate ester of morphine. ...
Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. ...
This article is about the drug. ...
Oripavine is an opiate and the major metabolite of thebaine. ...
Not to be confused with oxytocin. ...
Oxymorphone (Opana, Numorphan) or 14-Hydroxydihydromorphinone is a powerful semi-synthetic opioid analgesic that is derived from thebaine, and is approximately 6-8 times more potent than morphine. ...
Pantopon is a preparation of opiates made up of all of the alkaloids present in opium in their natural proportions as hydrochloride salts . ...
Papaveretum (BAN) is a preparation containing a mixture of hydrochloride salts of opium alkaloids. ...
Paregoric, or camphorated tincture of opium, is a medication known for its antidiarrheal, antitussive, and analgesic properties. ...
Pholcodeine is an opioid used primarily as an antitussant (to treat cough) with little abuse potential. ...
The chemical structure of dihydrocodeinone enol acetate Dihydrocodeinone Enol Acetate, or Thebacon, formerly marketed as its hydrochloride salt under the trade name Acedicon, is a semisynthetic opioid once used as an antitussive, primarily in Europe. ...
A minor constituent of opium, thebaine or paramorphine (C19H21NO3) is chemically similar to both morphine and codeine, but produces stimulatory rather than depressant effects. ...
| | Morphinans | Butorphanol • Cyclorphan • Dextro-3-hydroxy-N-allylmorphinan • Dextorphan • Levallorphan • Levorphanol • Levorphan • Levophenacylmorphan • Levomethorphan • Norlevorphanol • Phenomorphan • Racemethorphan Morphinan is the base chemical structures of a subgroup of opioids. ...
Butorphanol (INN) is a morphinan-type synthetic opioid analgesic marketed in the U.S. under the trade name Stadol. ...
Levorphanol is an opioid medication used to treat severe pain. ...
Levomethorphan is an optical isomer of dextromethorphan. ...
Phenomorphan is an opioid analgesic. ...
Racemethorphan is a racemic mixture of the stereoisomers of methorphan , namely dextromethorphan , which is the active ingredient in DM cough syrups , and the lesser known levomethorphan which is described as a controlled substance in The Merck Index - likely because it has more potential for abuse than its dextro enantiomer . ...
| | Benzomorphans | Cyclazocine • Dezocine • Ethylketocyclazocine • Ketazocine • Metazocine • Pentazocine • Phenazocine Cyclazocine is a mixed opiate agonist-antagonist. ...
Dezocine (Dalgan, WY-16225) is an opioid analgesic related to pentazocine, with a similar profile of effects that include analgesic action and euphoria at low doses,[1] but produces dysphoria and hallucinations at high doses, most likely due to action at κ-opioid receptors. ...
Ketazocine (INN) is a cyclazocine derivative used in opioid receptor research. ...
Metazocine is an opioid analgesic related to pentazocine. ...
Pentazocine is a synthetically-prepared narcotic drug used to treat mild to moderate pain. ...
| | 4-Phenylpiperidines | Anileridine • Carbetidine • Carperidine • Difenoxin • Diphenoxylate • Etoxeridine • Furethidine • Ipropethidine • Loperamide • Morpheridine • MPPP • Oxpheneridine • PEPAP • Pethidine (Meperidine) • Pethidine Intermediate A • Pethidine Intermediate B • Pethidine Intermediate C • Pheneridine • Phenoperidine • Piminodine • Properidine • Sameridine • Trimeperidine Anileridine (Leritine®) is a synthetic opioid and strong analgesic medication. ...
On opiod agonist used for the treatment of diarrhea. ...
Properidine is an opiate analgesic and the isopropyl analog of Meperidine. ...
Loperamide, usually as hydrochloride, is a drug effective against diarrhea resulting from gastroenteritis or inflammatory bowel disease. ...
MPPP (1-methyl 4-phenyl 4-propionoxypiperidine) is an opioid analgesic drug. ...
Pethidine (INN) or meperidine (USAN) (also referred to as: isonipecaine; lidol; pethanol; piridosal; Algil®; Alodan®; Centralgin®; Demerol®; Dispadol®; Dolantin®; Dolargan® (in Poland);[1] Dolestine®; Dolosal®; Dolsin®; Mefedina®) is a fast-acting opioid analgesic drug. ...
Phenoperidine is an opiod general anesthetic. ...
Properidine is an opiate analgesic and the isopropyl analog of Meperidine. ...
| | Prodines | α-prodine • Allylprodine • β-prodine • β-meprodine • Prodine • | | Bemidones | Bemidone • Hydroxypethidine • Ketobemidone • Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of pethidine (meperidine). ...
Ketobemidone structure Ketobemidone is a powerful opioid analgesic. ...
| | Anilidopiperidines | 3-methylfentanyl • 3-methylthiofentanyl • Alfentanil • α-methylacetylfentanyl • α-methylfentanyl • α-methylthiofentanyl • β-hydroxyfentanyl • β-hydroxythiofentanyl • Bezitramide • Brifentanil • Carfentanil • Fentanyl • Lofentanil • Ohmefentanyl • Parafluorofentanyl • Remifentanil • Sufentanil • Thiofentanyl • Trefentanil 3-Methylfentanyl (3-MF, mefentanyl) is an opioid analgesic that is an analogue of fentanyl. ...
3-methyl-thiofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
Alfentanil (Alfenta) is a parenteral short-acting opioid painkiller, used for anaesthesia in surgery. ...
α-methylacetylfentanyl is an opioid analgesic that is an analogue of fentanyl. ...
α-methylfentanyl is an opioid analgesic that is an analogue of fentanyl. ...
α-methyl-thiofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
β-hydroxyfentanyl is an opioid analgesic that is an analogue of fentanyl. ...
β-hydroxythiofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
Bezitramide (4-[4-(2-oxo-3-propanoyl-benzoimidazol-1-yl)-1-piperidyl]-2,2-diphenyl-butanenitrile MW: 492. ...
Brifentanil (A-3331) is an opioid analgesic that is an analogue of fentanyl and was developed in the early 1990s. ...
Carfentanil, also Carfentanyl, is an analogue of the popular opioid Fentanyl, and is currently the most potent opioid known [Actually Ohmefentanil is 13,000X morphine]. It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl (activity in humans starting at about 1...
Fentanyl is an opioid analgesic, first synthesized by Janssen Pharmaceutica (Belgium) in the late 1950s, with a potency many times that of morphine. ...
Lofentanil is an opioid analgesic that is an analogue of fentanyl and was developed in the early 1980s. ...
This article or section is not written in the formal tone expected of an encyclopedia article. ...
Para-fluorofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
Remifentanil is a potent ultra short-acting synthetic opioid analgesic drug. ...
Sufentanil is a synthetic opioid analgesic drug approximately 5 to 10 times more potent than fentanyl. ...
Thiofentanyl is an opioid analgesic that is an analogue of fentanyl. ...
Trefentanil (A-3665) is an opioid analgesic that is an analogue of fentanyl and was developed in the early 1990s. ...
| | Open chain opioids | β-acetylmethadol • Dextromethadone • Dextromoramide • Dextropropoxyphene • Diethylthiambutene • Dimethylthiambutene • Dipipanone • Ethylmethylthiambutene • Isomethadone • Lefetamine • Levo-α-acetylmethadol • Levomethadone • Levomoramide • Levopropoxyphene • Methadone • Methadone Intermediate • Moramide Intermediate • Noracymethadol • Norpipanone • Phenadoxone • Propoxyphene • Racemoramide Dextromoramide (Palfium®, Palphium®, Jetrium®, Dimorlin®) is the right-handed isomer of the moramide molecule. ...
Dextropropoxyphene is an analgesic in the opioid category. ...
Diethylthiambutene (N,N-Diethyl-1-methyl-3,3-di-2-thienylallylamine, Diethibutin, Themalon) is an opioid analgesic drug which was mainly used in veterinary medicine. ...
Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug. ...
Ethylmethylthiambutene (N-ethyl-N-methyl-1-methyl-3,3-di-2-thienylallylamine, Emethibutin) is an opioid analgesic drug. ...
Lefetamine is a psychoactive drug which has effects similar to both morphine and methylphenidate. ...
Levomethadyl acetate, also known as levo-α-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone. ...
The structure of Levopropoxyphene Levopropoxyphene is an antitussive. ...
Methadone is a synthetic opioid, used medically as an analgesic and in the treatment of narcotic addiction. ...
Phenadoxone (Heptalgin®) is an opioid analgesic of the open chain class (methadone and relatives) invented in Germany in 1947. ...
Dextropropoxyphene is an analgesic in the opioid category that is used to treat severe pain and severe coughs. ...
| | Oripavine derivatives | Acetorphine • Buprenorphine • Cyprenorphine • Dihydroetorphine • Diprenorphine • Etorphine Oripavine is an opiate and the major metabolite of thebaine. ...
Acetorphine is a potent analgesic drug (painkiller), several thousand times stronger than morphine by weight. ...
Buprenorphine, is an opioid drug with partial agonist and antagonist actions. ...
Cyprenorphine (M-285) is a drug which is an opioid derivative. ...
China is one of the only countries in the world to prescribe Dihydroetorphine, (a close relative of Etorphine) to humans. ...
Diprenorphine (Revivon, M5050) is an opiate antagonist used to reverse the effects of the super-potent opioid analgesics such as etorphine and carfentanil that are used for tranquilizing large animals in veterinary medicine. ...
Etorphine (Immobilon® or M99) is a synthetic cousin of morphine and 1000 - 80,000 times more powerful. ...
| | Phenalkoxams | Dextropropoxyphene • Dimenoxadol • Dioxaphetyl Butyrate • Dextropropoxyphene is an analgesic in the opioid category. ...
| | Ampromides | Diampromide • Phenampromide • Propiram • | | Others | Ciramadol • Clonitazene • Codomine • Dimepheptanol • Dithienylbutenyl dimethylamine • Drotebanol • Ethoheptazine • Etonitazene • Faxeladol • Heptazone • Meptazinol • Metheptazine • Narcotine • O-Desmethyltramadol • Picenadol • Piritramide • Proheptazine • Racemorphan • Semorphone • Tapentadol • Tilidine • Tramadol • Zipeprol Ciramadol (WY-15705) is an opioid analgesic that was developed in the late 1970s. ...
Etonitazene is a highly potent narcotic analgesic (1000-1500x morphine). ...
Faxeladol is an opioid analgesic. ...
Noscapine (also known as Narcotine) is an alkaloid opioid agonist from plants of the Papaveraceae family, without significant painkilling properties [1]. It is grouped as part of the benzylisoquinolines, of which papaverine is also included. ...
O-Desmethyltramadol (M1) is an opioid analgesic which is made in the body from tramadol. ...
Piritramide (Dipidolor®) is a synthetic opioid analgesic with about 65-75 percent of the mg-for-mg strength of morphine. ...
Tapentadol (INN) is a centrally-acting analgesic with a unique dual mode of action as an agonist at the μ-opioid receptor and as a norepinephrine reuptake inhibitor. ...
Tilidine (INN, USAN), or tilidate (BAN) (Valoron®, Valtran®, Tilidin) is a synthetic opioid analgesic, used for treatment of moderate to severe pain, both acute and chronic[1]. Considered a low- to medium-potency opioid, it has the oral potency of about 0. ...
Tramadol (INN) (IPA: ) is an atypical opioid which is a centrally acting analgesic, used for treating mild to moderate pain. ...
Zipeprol is a cough suppressant. ...
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