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Encyclopedia > Diproqualone

Diproqualone is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other european countries. It has sedative, anxiolytic, antihistamine and analgesic properties, and is used primarily for the treatment of inflammatory pain associated with osteoarthritis and rheumatoid arthritis[1], and more rarely for treating insomnia, anxiety and neuralgia. [2] Methaqualone tablets and capsules. ... A sedative is a substance which depresses the central nervous system (CNS), resulting in calmness, relaxation, reduction of anxiety, sleepiness, slowed breathing, slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes. ... An anxiolytic is a drug prescribed for the treatment of symptoms of anxiety. ... An antihistamine is a drug which serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions, through action at the histamine receptor. ... This article or section does not adequately cite its references or sources. ... Osteoarthritis (OA, also known as degenerative arthritis or degenerative joint disease, and sometimes referred to as arthrosis or osteoarthrosis or in more colloquial terms wear and tear), is a condition in which low-grade inflammation results in pain in the joints, caused by wearing of the cartilage that covers and... Rheumatoid arthritis (RA) is traditionally considered a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. ... This article is about the sleeping disorder. ... This article includes a list of works cited or a list of external links, but its sources remain unclear because it lacks in-text citations. ... Neuralgia is a painful disorder of the nerves. ...


Diproqualone is the only analogue of methaqualone that is still in widespread clinical use, due to its useful anti-inflammatory and analgesic effects in addition to the sedative and anxiolytic actions common to other drugs of this class. There are still some concerns about the potential of diproqualone for abuse and overdose, and so it is not sold as a pure drug but only as the camphosulfonate salt in combination mixtures with other medicines such as Ethenzamide. Ethenzamide is a common analgesic and antiinflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains. ...


Image:diproqualone.png


3-(2,3-dihydroxypropyl)-2-methyl-quinazolin-4-one


CAS number 36518-02-2 CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ...


See Also

Methaqualone tablets and capsules. ...

References

  1. ^ Audeval B, Bouchacourt P, Rondier J. Comparative study of diproqualone-ethenzamide versus glafenine for the treatment of rheumatic pain of gonarthrosis and coxarthrosis. (French) Gazette médicale de France 1988; 95(25):70-72
  2. ^ http://www.biam2.org/www/subMCCAMSILATE_DE_DIPROQUALONE.html


 
 

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