Directly Observed Treatment (DOT) or Directly Observed Therapy is watching the patient take his/her medication to ensure medications are taken in the right combination and for the correct duration. It is used for diseases such as tuberculosis or HIV to assure compliance and avoid drug resistance.
Also, DOTS (Directly Observed Treatment, Short-course). The brand name given to the WHO-recommended TB control strategy that combines five components: government commitment, case detection by sputum smear microscopy, standardized treatment regimen with directly observed treatment for at least the first two months, a regular drug supply, and a standardized recording and reporting sysystem that allows assessment of treatment results.
DOTS-PLUS for multidrug-resistant tuberculosis (MDR-TB).
Reference
What is DOTS? (http://www.who.int/gtb/publications/whatisdots/index.htm) A guide to Understanding the WHO-recommended TB Control Strategy Known as DOTS by World Health Organization 1999
External link
DOTS program (http://www.who.int/gtb/dots/) WHO - DOTS
This report summarizes evaluations of treatment outcomes for patients enrolled during the first 6 months of the project in Orel oblast and indicates that treatment success rates among TB patients in Orel were high.
Treatment success (i.e., patients with bacteriologically documented cure and those who completed treatment) was attained for 88% of new and 60% of retreatment TB patients.
The higher treatment success rates among Orel patients in whom asymptomatic TB was diagnosed using chest radiograph (without bacteriologic confirmation) compared with those with bacteriologic confirmation may reflect either early diagnosis of disease or incorrect diagnosis.
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