? IUPAC nomenclature is a systematic way of naming organic chemical compounds. ... CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ... The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ... A section of the Anatomical Therapeutic Chemical Classification System. ... PubChem is a database of chemical molecules . ... DrugBank is a database available at the University of Alberta that provides information about thousands of products. ... A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ... The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ... In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ... Santorio Santorio (1561-1636) in his steelyard balance, from Ars de statica medecina, first published 1614 Metabolism (from μεταβολισμος (metabolismos)) is the biochemical modification of chemical compounds in living organisms anggjgjhnd cell (b). ... The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ... Excretion is the biological process by which an organism chemically separates waste products from its body. ... The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother. ...
Dirithromycin is a macrolideglycopeptide antibiotic. The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ... In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ... The macrolides are a group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, are attached. ... Glycopeptide antibiotics are a class of antibiotic drugs. ...
External links
Duran D, Aviyente V, Baysal C (2004). "A computational approach to the synthesis of dirithromycin.". J Mol Model (Online)10 (2): 94-101. PMID 14722740.
Castaldo R, Celli B, Gomez F, LaVallee N, Souhrada J, Hanrahan J (2003). "A comparison of 5-day courses of dirithromycin and azithromycin in the treatment of acute exacerbations of chronic obstructive pulmonary disease.". Clin Ther25 (2): 542-57. PMID 12749513.
Mazzei T, Surrenti C, Novelli A, Biagini M, Fallani S, Cassetta M, Conti S, Surrenti E (1999). "Pharmacokinetics of dirithromycin in patients with mild or moderate cirrhosis.". Antimicrob Agents Chemother43 (7): 1556-9. PMID 10390202.
J01FA: Macrolides {01-Erythromycin} {08-Troleandomycin} {09-Clarithromycin} {10-Azithromycin} {13-Dirithromycin} Wikipedia does not yet have an article with this exact name. ... A section of the Anatomical Therapeutic Chemical Classification System. ... A section of the Anatomical Therapeutic Chemical Classification System. ... The macrolides are a group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, are attached. ... Erythromycin is a macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins - this is not necessarily a good idea , as after all , erythromycin is itself a penicillin derivative. ... Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia (especially atypical pneumonias associated with Chlamydia pneumoniae or TWAR), skin and skin structure infections, and, in HIV and AIDS patients to prevent, and to treat, disseminated Mycobacterium avium complex or... Azithromycin is an azalide, a subclass of macrolide antibiotics. ...
Others: {DF01-Aztreonam/Monobactam} {XA01-Vancomycin} {XA02-Teicoplanin} Categories: Stub | Monobactam antibiotics ... Vancomycin is an antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive bacteria. ... Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria. ...
Dirithromycin is known to crystallize as a solvated crystal from acetonitrile; however, the acetonitrile solvate of dirithromycin is known to be unstable.
The Form II dirithromycin may be prepared via the acetone, 1-butanol, 1-propanol, or 2-propanol solvates of dirithromycin or from Form I. These solvates of dirithromycin, are novel compounds that facilitate the isolation of pharmaceutically acceptable dirithromycin Form II by removing impurities, as demonstrated by HPLC chromatogram.
Dirithromycin (Form II), magnesium carbonate, microcrystalline cellulose, sodium starch glycolate, hydroxypropyl cellulose, and magnesium stearate are thoroughly blended in a ribbon mixer or other type of suitable mixer such as a V-blender, conical mixer, etc. The resulting powder mixture is compacted using a roller compactor or equivalent dry granulating equipment.
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