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A dissociative is a drug which reduces (or blocks) signals to the conscious mind from other parts of the brain, typically, but not necessarily, or limited to the physical senses. Such a state of sensory deprivation and dissociation can facilitate self exploration, hallucinations, and dreamlike states of mind which may resemble some psychedelic mindstates. Essentially similar states of mind can be reached via contrasting paths—psychedelic or dissociative. That said, the entire experience, risks and benefits are markedly different. Senses are the physiological methods of perception. ...
A prisoner at the United States Camp X-ray facility at Guantanamo Bay in Cuba being subjected to sensory deprivation, through the use of ear muffs, visor, breathing mask and heavy mittens. ...
Dissociation is a psychological state or condition in which certain thoughts, emotions, sensations, or memories are separated from the rest of the psyche. ...
An hallucination is a sensory perception experienced in the absence of an external stimulus, as distinct from an illusion, which is a misperception of an external stimulus. ...
Pierre-Cécile Puvis de Chavannes: The Dream, 1883 A dream is the experience of envisioned images, voices, or other sensations during sleep. ...
The word psychedelic is a neologism coined from the Greek words for mind, ψυχη (psyche), and manifest, δηλειν (delein). ...
The primary dissociatives are similar in action to phencyclidine (PCP), and include ketamine and dextromethorphan. Also included are nitrous oxide (laughing gas), salvia divinorum, and muscimol from the amanita muscaria (fly agaric) mushroom. Phencyclidine (a contraction of the chemical name phenylcyclohexylpiperidine), abbreviated PCP, is a dissociative drug formerly used as an anaesthetic agent, exhibiting hallucinogenic and neurotoxic effects. ...
For the collaborative acoustic project, see Katamine. ...
Dextromethorphan (DM or DXM) is an antitussive drug that is found in many over-the-counter cold and cough preparations, usually in the form of dextromethorphan hydrobromide. ...
This article is about nitrous oxide, or laughing gas. ...
Binomial name Salvia divinorum Salvia divinorum (also known as Diviners sage, Magic Mint, MarÃa Pastora, or simply Salvia, although the genus name is shared among many plants) is a psychoactive plant, a member of the sage genus and the Lamiaceae (mint) family. ...
Muscimol (agarin, pantherine) is the psychoactive compound present in Amanita muscaria and Amanita Pantherina. ...
Binomial name Amanita muscaria (Linnaeus) Hook. ...
Many dissociatives also have central nervous system depressant effects, thereby carrying similar risks as opioids to slowing breathing or heart rate to levels resulting in death, when using very high doses. A diagram showing the CNS: 1. ...
See also sedative. ...
An opioid is any agent that binds to opioid receptors found principally in the central nervous system and gastrointestinal tract. ...
Heart rate is a term used to describe the frequency of the cardiac cycle. ...
Death is the full cessation of vital functions in the biological life. ...
Their effects are characterized by intense feelings of depersonalization, derealization, and analgesia. It has been suggested that Depersonalization disorder be merged into this article or section. ...
For other uses of painkiller, see painkiller (disambiguation) An analgesic (colloquially known as painkiller) is any member of the diverse group of drugs used to relieve pain. ...
Pharmacological classes of dissociatives, and their general subjective effects Entries marked with a # are naturally occurring.
NMDA receptor antagonists and sigma1 ligands NMDA (N-methyl-D-aspartic acid) is an amino acid derivative acting as specific agonist at the NMDA receptor, and therefore mimics the action of the neurotransmitter glutamate on that receptor. ...
Dextromethorphan (DM or DXM) is an antitussive drug that is found in many over-the-counter cold and cough preparations, usually in the form of dextromethorphan hydrobromide. ...
For the collaborative acoustic project, see Katamine. ...
The psychedelic (from the Greek words for mind, ψυχη psyche, and manifest, δηλειν delein) drugs are classified as those whose primary action is that of enhancing or amplifying the thought processes of the brain. ...
Phencyclidine (a contraction of the chemical name phenylcyclohexylpiperidine), abbreviated PCP, is a dissociative drug formerly used as an anaesthetic agent, exhibiting hallucinogenic and neurotoxic effects. ...
Ibogaine is an indole alkaloid, a strong hallucinogen which has gained attention due to its application in the treatment of opioid addiction and similar addiction syndromes. ...
The psychedelic (from the Greek words for mind, ψυχη psyche, and manifest, δηλειν delein) drugs are classified as those whose primary action is that of enhancing or amplifying the thought processes of the brain. ...
Dizocilpine (also known as MK-801) is a non-competitive NMDA receptor antagonist. ...
Riluzole is a drug used to treat amyotrophic lateral sclerosis. ...
Opioid receptors are a group of G-protein coupled receptors with opioids as ligands. ...
Salvinorin A is the main active psychotropic constituent of the plant Salvia divinorum (diviners sage, Mexican mint), which has a long history of use as an entheogen. ...
Binomial name Salvia divinorum Salvia divinorum (also known as Diviners sage, Magic Mint, MarÃa Pastora, or simply Salvia, although the genus name is shared among many plants) is a psychoactive plant, a member of the sage genus and the Lamiaceae (mint) family. ...
Binomial name Salvia divinorum Salvia divinorum (also known as diviners sage or simply salvia) is a psychoactive plant, a member of the sage genus and the Lamiaceae (mint) family. ...
Ibogaine is an indole alkaloid, a strong hallucinogen which has gained attention due to its application in the treatment of opioid addiction and similar addiction syndromes. ...
Inhalants This article is about nitrous oxide, or laughing gas. ...
These four groups of dissociatives have slightly different effects but also share similarities separating them from other classes of hallucinogens. They are markedly different from psychedelics such as LSD, where alert and fully conscious users experience cognitive distortion while simultaneously interacting with the "real world". Hallucinations from these dissociatives are generally only experienced in dark rooms or with eyes closed, unless at very high doses above what is normally consumed recreationally. Nitrous oxide has very different effects however, and even at low doses includes auditory distortions. Unlike with many other psychedelic chemicals, salvia users are generally not ambulatory and the experience is frequently dissociative. Often a very brief trance is entered, where the user experiences an intense and very realistic dream state. On the other hand, the effect of salvia on emotion has been reported to be less marked than that of true psychedelics. Binomial name Amanita muscaria (Linnaeus) Hook. ...
Muscimol (agarin, pantherine) is the psychoactive compound present in Amanita muscaria and Amanita Pantherina. ...
The GABA-a pentameric receptor The GABAA receptor is one of the three ligand-gated ion channels responsible for mediating the effects of Gamma-AminoButyric Acid (GABA), the major inhibitory neurotransmitter in the human body. ...
Categories: Stub | Amino acids ...
Muscarine, L-(+)-muscarine, or muscarin is a natural product found in certain mushrooms, particularly in Inocybe and Clitocybe species. ...
Muscarinic receptors are those membrane-bound acetylcholine receptors that are more sensitive to muscarine than to nicotine. ...
To meet Wikipedias quality standards, this article or section may require cleanup. ...
For other uses, see LSD (disambiguation). ...
It has been suggested that Feeling be merged into this article or section. ...
Although muscimol does not usually cause normal hallucinations, it has a tendency to put the user to sleep, during which the user is able to have very vivid dreams with good dream recall.
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