Dixon Hall Lewis (August 10, 1802–October 25, 1848) was an American politician who served as a Representative and a Senator from Alabama.

Lewis was born on Bothwick plantation, Dinwiddie County, Virginia, and moved to Hancock County, Georgia, with his parents in 1806. He graduated from Mount Zion Academy and from South Carolina College at Columbia in 1820. He moved to Autauga County, Alabama, the same year, where he studied law and was admitted to the bar in 1823. He began to practice law in Montgomery, Alabama, and was elected a member of the State house of representatives in 1826, serving until 1828. He was elected as a States Rights Democrat to the Twenty-first and to the seven succeeding Congresses and served from March 4, 1829, to April 22, 1844, when he resigned, having been appointed Senator. In the House, he served as chairman of the Committee on Indian Affairs from 1831 to 1835.

Lewis was appointed and subsequently elected as a Democrat to the United States Senate to fill the vacancy caused by the resignation of William R. King in 1844. He was reelected in 1847 and served from April 22, 1844, until his death in New York City on October 25, 1848. In the Senate he served as chairman of the Finance Committee (1845-1847).