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Encyclopedia > Docetaxel
Docetaxel chemical structure
Docetaxel chemical structure

Docetaxel is a chemotherapy drug used in the treatment of cancer. It has been developed after the related drug, paclitaxel. It is derived from a species of yew, Taxus baccata. Together with paclitaxel, it forms the drug category of the taxanes. Image File history File links Docetaxel, chemical structure. ... Image File history File links Docetaxel, chemical structure. ... A medication is a licenced drug taken to cure or reduce symptoms of an illness or medical condition. ... When normal cells are damaged beyond repair, they are eliminated by apoptosis. ... Paclitaxel is a drug used in the treatment of cancer. ... Species Taxus baccata - European Yew Taxus brevifolia - Pacific (or Western) Yew Taxus canadensis - Canadian Yew Taxus chinensis - Chinese Yew Taxus cuspidata - Japanese Yew Taxus floridana - Florida Yew Taxus globosa - Mexican Yew Taxus sumatrana - Sumatran Yew Taxus wallichiana - Himalayan Yew Taxus is a genus of yews, small coniferous trees or shrubs... Binomial name Taxus baccata L. Taxus baccata is a conifer native to western, central and southern Europe, northwest Africa, northern Iran and southwest Asia. ... Paclitaxel is a drug used in the treatment of cancer. ... The taxanes are a widely used class of chemotherapy drugs. ...


It is mainly used in lung cancer, breast cancer, as well as in prostate cancer. The incidence of lung cancer is highly correlated with smoking. ... Breast cancer is cancer of breast tissue. ... Prostate cancer is a disease in which cancer develops in the prostate, a gland in the male reproductive system. ...


It is marketed as Taxotere in the U.S.



Chemotherapeutic agents edit - Chemotherapy regimens

ALKYLATING AGENTS: {Busulfan} {Carboplatin} {Chlorambucil} {Cisplatin} {Cyclophosphamide} {Ifosfamide} {Melphalan} {Mechlorethamine} {Oxaliplatin} {Uramustine} Chemotherapy is the use of chemical substances to treat disease. ... Chemotherapy regimens are often identified with acronyms, identifying the agents used in combination. ... Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. ... Busulfan is a chemotherapy drug that is an alkylating agent. ... |} Carboplatin is a chemotherapy drug used against some form of cancer. ... Chlorambucil (marketed as Leukeran) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. ... Cisplatin or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e. ... Cyclophosphamide is a nitrogen mustard alkylating agent, used to treat various types of cancer and some autoimmune disorders. ... Ifosfamide (Mitoxana®) Ifosfamide (pronounced i fos fa mide) is chemotherapy that is given as a treatment for many different types of cancer. ... Melphalan chemical structure Melphalan hydrochloride ( Alkeran®) is a chemotherapy drug belonging to the class of alkylating agents. ... Mechloretamine: chemical structure Mechlorethamine also known as nitrogen mustard and HN2 and sold under the brand name Mustargen, is the first anticancer drug to be widely used clinically. ... Oxaliplatin - Wikipedia /**/ @import /w/skins-1. ...


ANTI-METABOLITES: {Azathioprine} {Capecitabine} {Cytarabine} {Fludarabine} {Fluorouracil} {Gemcitabine} {Methotrexate} {Pemetrexed} An antimetabolite is a chemical with a similar structural to a substance (a metabolite) required for normal biochemical reactions, yet different enough to interfere with the normal functions of cells, including cell division. ... Azathioprine is a chemotherapy drug, now rarely used for chemotherapy but more for immunosuppression in organ transplantation and autoimmune disease such as rheumatoid arthritis or inflammatory bowel disease or Crohns disease. ... Capecitabine - Wikipedia /**/ @import /w/skins-1. ... Cytarabine is a shortened form of cytosine arabinoside, a commonly used chemotherapy agent used mainly in the treatment of leukemia and non-Hodgkin lymphoma. ... Fludarabine is a chemotherapy drug used in the firstline treatment of chronic lymphocytic leukemia. ... Fluorouracil (5-FU) is a drug that is used in the treatment of cancer. ... Gemcitabine is a nucleoside used as chemotherapy. ... Methotrexate (abbreviated MTX; formerly known as amethopterin) is an antimetabolite drug used in treatment of cancer and autoimmune disease. ... Pemetrexed chemical structure Pemetrexed (brand name Alimta) is a chemotherapy drug. ...


PLANT ALKALOIDS: {Docetaxel} {Etoposide} {Paclitaxel} {Vinblastine} {Vincristine} (Vinorelbine) An alkaloid is a nitrogenous organic molecule that has a pharmacological effect on humans and animals. ... Etoposide: chemical structure Etoposide phosphate (Eposin®, Etopophos®, Vepesid®, VP-16®) is an inhibitor of the enzyme topoisomerase II. It is used as a form of chemotherapy for malignancies such as lung cancer, testicular cancer, lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme. ... Paclitaxel is a drug used in the treatment of cancer. ... Vinblastine: chemical structure Vinblastine is a drug used to treat certain kinds of cancer, including lymphoma and breast cancer or testicular cancer. ... Vincristine (Oncovin®) is an alkaloid from the Madagascar periwinkle (Catharanthus roseus, formerly Vinca rosea and hence its name). ... Vinorelbine (Navelbine) is a chemotherapy drug that is given as a treatment for some types of cancer including breast cancer and non-small-cell lung cancer. ...


TOPOISOMERASE INHIBITORS: {Irinotecan} {Topotecan} Topoisomerases (type I: EC 5. ... Irinotecan is a chemotherapy agent that is a topoisomerase 1 inhibitor. ...


ANTITUMOUR ANTIBIOTICS: {Bleomycin} {Daunorubicin} {Doxorubicin} {Epirubicin} {Hydroxyurea} {Idarubicin} {Mitomycin} {Mitoxantrone} herbs that have the specific action of inhibiting and combating the development of tumors. ... Bleomycin is an anti-cancer agent. ... Daunorubicin is chemotherapy that is given as a treatment for some types of cancer. ... Doxorubicin is a pharmaceutical drug widely used in cancer chemotherapy. ... Epirubicin is an anthracycline drug used for chemotherapy. ... Hydroxyurea chemical structure Hydroxyurea or hydroxycarbamide (rINN), (brand names include Hydrea®) is an antineoplastic drug used in hematological malignancies. ... Idarubicin chemical structure Idarubicin or 4-demethoxydaunorubicin is an anthracycline drug that is used in the treatment of cancer. ... Mitomycin or mitomycin C is a form of chemotherapy given intravenously to treat upper gastro-intestinal (e. ... Mitoxantrone belongs to the general group of medicines known as antineoplastics, specifically the anthracycline class. ...


  Results from FactBites:
 
Docetaxel: Encyclopedia of Cancer (752 words)
Docetaxel is an antineoplastic agent used to treat breast cancer and non-small cell lung carcinoma.
Docetaxel is a synthetic derivative of the naturally occurring compound paclitaxel.
Docetaxel should not be administered to patients who are known to have severe hypersensitivity to polysorbate 80, which is a component of the treatment that helps dissolve the drug.
CancerNetwork: (3374 words)
The docetaxel (Taxotere)-containing regimens were developed following one of three important strategies: (1) the sequential administration of docetaxel to existing, commonly used combinations; (2) the simultaneous addition of docetaxel to an existing regimen; and (3) the substitution of docetaxel for one of the drugs included in standard combinations.
Docetaxel is active in NSCLC and should be investigated further in combination with novel molecularly targeted drugs such as tyrosine kinase inhibitors, and farnesyl transferase inhibitors.
Preclinical data indicate that docetaxel is a potent radiosensitizer and its initial evaluation with concurrent radiation in patients with locally advanced unresectable squamous cell cancer of the head and neck suggests feasibility.
  More results at FactBites »


 
 

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