Granuloma inguinale or Donovanosis is a bacterialdisease caused by the organism Calymmatobacterium granulomatis. The disease is commonly found in tropical and subtropical areas such as Southeast India, Guyana, and New Guinea, but it occurs on occasion in the United States, typically in the Southeast. There are approximately 100 cases reported per year in the United States.
Men are affected more than twice as often as women, with most infections occurring in people aged 20 to 40 years. The disease is seldom seen in children or the elderly.
It is thought that anal intercourse, rather than vaginal intercourse, is the most frequent source of infection. About 50 percent of infected men and women have lesions in the anal area.
External link
U.S. NIH on Granuloma inguinale (http://www.nlm.nih.gov/medlineplus/ency/article/000636.htm)
Although donovanosis is an intrinsically benign condition effectively treated by numerous antibiotics, the disease is associated with substantial morbidity and mortality.
Pudendal lesions of donovanosis are usually red as opposed to pale condylomata lata of secondary syphilis.
Extragenital lesions are estimated to occur in approximately 6% of cases of donovanosis but many more cases probably remain undetected because of diverse non-specific presentations and a low index of suspicion.
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