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Dosulepin hydrochloride (sometimes known outside the USA as dothiepin hydrochloride) is an antidepressant of the tricyclic family. IUPAC nomenclature is a systematic way of naming organic chemical compounds. ...
CAS registry numbers are unique numerical identifiers for chemical compounds, polymers, biological sequences and alloys. ...
The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
PubChem is a database of chemical molecules . ...
A chemical formula (also called molecular formula) is a concise way of expressing information about the atoms that constitute a particular chemical compound. ...
General Name, Symbol, Number carbon, C, 6 Chemical series nonmetals Group, Period, Block 14, 2, p Appearance black (graphite) colorless (diamond) Atomic mass 12. ...
General Name, Symbol, Number hydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1, 1, s Appearance colorless Atomic mass 1. ...
General Name, Symbol, Number nitrogen, N, 7 Chemical series nonmetals Group, Period, Block 15, 2, p Appearance colorless Atomic mass 14. ...
General Name, Symbol, Number sulfur, S, 16 Chemical series nonmetals Group, Period, Block 16, 3, p Appearance lemon yellow Atomic mass 32. ...
General Name, Symbol, Number chlorine, Cl, 17 Chemical series halogens Group, Period, Block 17, 3, p Appearance yellowish green Atomic mass 35. ...
The molecular mass of a substance (less accurately called molecular weight and abbreviated as MW) is the mass of one molecule of that substance, relative to the unified atomic mass unit u (equal to 1/12 the mass of one atom of carbon-12). ...
In pharmacology, bioavailability is used to describe the fraction of an administered dose of medication that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. ...
Santorio Santorio (1561-1636) in his steelyard balance, from Ars de statica medecina, first published 1614 Metabolism (from μεÏαβολιÏÎ¼Î¿Ï (metabolismos)) is the biochemical modification of chemical compounds in living organisms anggjgjhnd cell (b). ...
The elimination half-life of a drug (or any xenobiotic agent) refers to the timecourse necessary for the quantity of the xenobiotic agent in the body (or plasma concentration) to be reduced to half of its original level through various elimination processes. ...
Excretion is the biological process by which an organism chemically separates waste products from its body. ...
The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother. ...
The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction. ...
In pharmacology and toxicology, a route of administration is the path by which a drug, fluid, poison or other substance is brought into contact with the body 1. ...
An antidepressant is a medication designed to treat or alleviate the symptoms of clinical depression. ...
Chemical structure of the tricyclic antidepressant amitriptyline Tricyclic antidepressants are a class of antidepressant drugs first used in the 1950s. ...
Dosulepin is relatively mild and is used for low level anxiety depression and similar disorders, particularly where insomnia and/or loss of appetite are present. It can take between two and four weeks of regular usage to become effective, it is often started at a low level and the dosage increased if this is ineffective. The drug causes drowsiness as a side-effect, and this may be used as part of the treatment, since anxiety depressive patients may have difficulty sleeping, but it can be combined with other drugs such as temazepam. To meet Wikipedias quality standards, this article or section may require cleanup. ...
It is recommended that patients on Dosulepin avoid alcohol while taking the medication as this may increase some side-effects. Dosulepin is not addictive, but should not be stopped suddenly or without consulting your physician. There are potential side-effects from ceasing the drug.
Side-effects
The commonest side-effects are drowsiness and dry mouth. Other less common side-effects may include: These side-effects cease when treatment ceases. Constipation or irregularity, is a condition of the digestive system where a person (or animal) experiences hard feces that are difficult to eliminate; it may be extremely painful, and in severe cases (fecal impaction) lead to symptoms of bowel obstruction. ...
Tachycardia is an abnormally rapid beating of the heart, defined as a resting heart rate of 100 or more beats per minute in an average adult. ...
Urinary retention is a lack of ability to urinate. ...
For other uses, see Tremor (disambiguation). ...
In physiology and medicine, hypotension refers to an abnormally low blood pressure. ...
Sexual problems, also called sexual dysfunction or sexual malfunction, are defined as difficulty during any stage of the sexual act (which includes desire, arousal, orgasm, and resolution) that prevents the individual or couple from enjoying sexual activity. ...
Sweating (also called perspiration or sometimes transpiration) is the loss of a watery fluid, consisting mainly of sodium chloride (commonly known as salt) and urea in solution, that is secreted by the sweat glands in the skin of mammals. ...
Possible side-effects of aprupt withdrawal include: - nausea
- vomiting
- loss of appetite
- headache
- giddiness
- chills
- insomnia
- anxiety
This list also includes some of the symptoms which are indications for the drug in the first place.
Contra-indications Contra-indications include: The drug can interact dangerously with vasoconstrictors and should not be taken in combination with phenylephrine or adrenaline in particular. Other specific contra-indications include monoamine oxidase inhibitor antidepressants (MAOI) (treatment should not be started until 2 weeks after stopping a MAOI); any selective serotonin reuptake inhibitor antidepressants (SSRI, e.g. fluoxetine); and any medication which affects the electrical impulses to the heart (e.g. astemizole, halofantrine or terfenadine). A cardiac arrhythmia, also called cardiac dysrhythmia, is a disturbance in the regular rhythm of the heartbeat. ...
A myocardial infarction occurs when an atherosclerotic plaque slowly builds up in the inner lining of a coronary artery and then suddenly ruptures, totally occluding the artery and preventing blood flow downstream. ...
Mania is a medical condition characterised by severely elevated mood. ...
The liver is an organ in vertebrates including humans. ...
The thyroid gland and its relations The thyroid is one of the larger endocrine glands in the body. ...
A pheochromocytoma (also phaeochromocytoma, English spelling) is a tumor in the medulla of the adrenal glands (or, rarely, the ganglia of the sympathetic nervous system) which secretes excessive amounts of catecholamines, usually epinephrine and norepinephrine. ...
This article is about the disease that features high blood sugar. ...
In physiology and medicine, hypotension refers to an abnormally low blood pressure. ...
Urinary retention is a lack of ability to urinate. ...
This article is about the disease. ...
Vasoconstriction is the constriction of blood vessels, in other words, when the lumen narrows. ...
Phenylephrine or neosynephrine is an α-agonist used primarily as a decongestant, as an agent to dilate the pupil, and rarely to increase blood pressure. ...
Epinephrine (INN) or adrenaline (BAN) is a hormone and a neurotransmitter. ...
Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. ...
Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants. ...
Fluoxetine hydrochloride is an antidepressant drug used medically in the treatment of depression, obsessive-compulsive disorder, bulimia nervosa, premenstrual dysphoric disorder and panic disorder. ...
Astemizole is a second generation antihistamine that has a long duration of action. ...
Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. ...
The drug is not recommended for use by children, and you should always consult a doctor before taking this or any other medication. Dosulepin is not recommended to be taken in combination with some other drugs, including herbal remedies. Caution should be used when taking any over-the-counter medications in combination with Dosulepin; if in doubt consult your pharmacist or doctor.
| | | Monoamine oxidase inhibitors (MAOI): {Harmaline} {Nialamide} {Selegiline} {Isocarboxazid} {Iproniazid} {Iproclozide} {Phenelzine} {Toloxatone} {Tranylcypromine} Reversible Inhibitor of Monoamine oxidase A (RIMA): {Brofaromine} {Moclobemide} An antidepressant is a medication designed to treat or alleviate the symptoms of clinical depression. ...
A section of the Anatomical Therapeutic Chemical Classification System. ...
Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. ...
Monoamine oxidase inhibitors (MAOIs) are a class of antidepressant drugs prescribed for the treatment of depression. ...
Harmala, also known at various times as Telepathine and Banisterine, is a blanket term for a group of naturally occurring beta-carbolines including harmine, harmaline, and others. ...
Nialamide (Espril®, Niamid®, Niaquitil®, Nuredal®, Nyazin®, and Psicodisten®) was one of the first MAOI (monoamine oxidase inhibitor) antidepressants. ...
Selegiline (l-deprenyl, Eldepryl® or Anipryl® [veterinary]) is a drug used for the treatment of early-stage Parkinsons disease and senile dementia. ...
Isocarboxazid is a nonselective hydrazine-derived monoamine oxidase inhibitor used in treatment resistant depression. ...
Iproniazid is a monamine oxidase inhibitor (MAOI) that was developed as the first anti-depressant (Also first psychiatric drug). ...
Phenelzine (brand name Nardil) is an antidepressant drug that belongs to the monoamine oxidase inhibitor (MAOI) class of drugs. ...
Tranylcypromine is an antidepressant drug. ...
These drugs, a subset of monoamine oxidase inhibitors (MAOIs), inhibit only isoenzyme A and are reversible. ...
These drugs, a subset of monoamine oxidase inhibitors (MAOIs), inhibit only isoenzyme A and are reversible. ...
Brofarmine is a psychiatric drug primarily used to treat depression and anxiety. ...
Moclobemide (sold as Aurorix®, Manerix®) is a psychiatric drug primarily used to treat depression and social anxiety. ...
Dopamine Reuptake Inhibitor (DARI): {Amineptine} {Methylphenidate} {Phenmetrazine} {Vanoxerine} {Nomifensine} This article or section does not cite its references or sources. ...
Amineptine is an atypical tricyclic antidepressant that selectively inhibits the reuptake of dopamine and to a lesser extent norepinephrine, thus exerting a powerful and fast-acting antidepressant effect. ...
Methylphenidate (MPH) is an amphetamine-like prescription stimulant commonly used to treat Attention Deficit Hyperactivity Disorder (ADHD) in children and adults. ...
Phenmetrazine is an amphetamine-like drug. ...
Vanoxerine, also known as GBR-12909, is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. ...
Nomifensine is a dopamine reuptake inhibitor that increases the amount of synaptic dopamine available to receptors by blocking dopamines re-uptake transporter. ...
Norepinephrine-dopamine reuptake inhibitors: {Bupropion} A Norepinephrine-dopamine reuptake inhibitor is a class of drugs that is both: Dopamine reuptake inhibitor Norepinephrine reuptake inhibitor An example is Bupropion. ...
Bupropion (amfebutamone) (brand names Wellbutrin and Zyban) is an antidepressant of the aminoketone class, chemically unrelated to tricyclics or selective serotonin reuptake inhibitors (SSRIs). ...
Norepinephrine Reuptake Inhibitor (NRI) or (NARI): {Atomoxetine} {Reboxetine} {Viloxazine} {Maprotiline} Norepinephrine reuptake inhibitors (NRIs) are compounds that increase amounts of the neurotransmitter norepinephrine in the brain by inhibiting its reuptake at synapses. ...
Atomoxetine is a drug used in the treatment of attention-deficit hyperactivity disorder (ADHD). ...
Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesilate ( methanesulfonate) salt is sold under tradenames including Edronax®, Norebox®, Prolift®, Solvex® or Vestra®. Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine. ...
Viloxazine is a bicyclic antidepressants[2] that inhibits the reuptake of serotonin, and to a lesser extent, dopamine and norepinephrine. ...
To meet Wikipedias quality standards, this article may require cleanup. ...
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI): {Desipramine} {Duloxetine} {Milnacipran} {Venlafaxine} Serotonin-norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant used in the treatment of clinical depression and other affective disorders. ...
Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. ...
Duloxetine hydrochloride (brand names: Cymbalta/Yentreve) is a medically used drug that primarily targets major depressive disorders (MDD), pain related to diabetic peripheral neuropathy and stress urinary incontinence (SUI). ...
Milnacipran is an antidepressant of the serotonin-norepinephrine reuptake inhibitor class. ...
Venlafaxine hydrochloride is a prescription antidepressant first introduced by Wyeth in 1993. ...
Selective Serotonin Reuptake Inhibitor (SSRI): {Alaproclate} {Etoperidone} {Citalopram} {Escitalopram} {Fluoxetine} {Fluvoxamine} {Paroxetine} {Sertraline} {Zimelidine} Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants for treating depression, anxiety disorders and some personality disorders. ...
Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants for treating depression, anxiety disorders and some personality disorders. ...
Alaproclate is an antidepressant that increases serotonin levels by inhibiting the uptake of 5-HT. Today, its primarily used to stagment the cravings for cocaine. ...
Etoperidone is a 5-HT agonist used primarily in the 1970s to impede the effects of LSD. ...
Citalopram or nitalapram is an antidepressant drug used to treat the depression associated with mood disorders. ...
Escitalopram is a medication developed by the Danish pharmaceutical company Lundbeck, that acts as a selective serotonin reuptake inhibitor or SSRI. It is typically used as an antidepressant to treat depression associated with mood disorders although also may be used in the treatment of body dysmorphic disorder and anxiety. ...
Fluoxetine hydrochloride is an antidepressant drug used medically in the treatment of depression, obsessive-compulsive disorder, bulimia nervosa, premenstrual dysphoric disorder and panic disorder. ...
Fluvoxamine maleate (sold under the brand-names Luvox® and Faverin®) is a selective serotonin reuptake inhibitor. ...
To meet Wikipedias quality standards, this article or section may require cleanup. ...
Sertraline hydrochloride (Zoloft®, Sertralin®, Lustral®, Apo-Sertral®, Asentra®, Gladem®, Serlift®, Stimuloton®, Xydep®, Serlain®, Concorz®) is an orally administered antidepressant of the selective serotonin reuptake inhibitor (SSRI) type. ...
// General Remars and History Zimelidine is a pyridylallylamine and has a structure different from other antidepressants. ...
Selective Serotonin Reuptake Enhancer (SSRE): {Tianeptine} Tianeptine (INN) (Stablon®, Coaxil®, Tatinol®), is structurally similar to the tricyclic antidepressants. ...
Tianeptine (INN) (Stablon®, Coaxil®, Tatinol®), is structurally similar to the tricyclic antidepressants. ...
Tianeptine (INN) (Stablon®, Coaxil®, Tatinol®), is an SSRE, or Selective Serotonin Reuptake Enhancer, structurally similar to the tricyclic antidepressants. ...
Tricyclic antidepressants (TCA): {Amitriptyline} {Butriptyline} {Clomipramine} {Desipramine} {Dothiepin} {Doxepin} {Imipramine} {Lofepramine} {Nortriptyline} {Protriptyline} {Trimipramine} {Iprindole} {Opipramol} {Amoxapine} Chemical structure of the tricyclic antidepressant amitriptyline Tricyclic antidepressants are a class of antidepressant drugs first used in the 1950s. ...
Chemical structure of the tricyclic antidepressant amitriptyline Tricyclic antidepressants are a class of antidepressant drugs first used in the 1950s. ...
Amitriptyline hydrochloride is an antidepressant drug from the tricyclic antidepressant group, which is sold under the trade names Elavil®, Tryptanol® or Endep®. It is a white, odorless, crystalline compound which is freely soluble in water. ...
Clomipramine (brand-name Anafranil®) is a tricyclic antidepressant. ...
Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. ...
Doxepin is a tricyclic antidepressant, known under many brand-names such as Aponal®, the original preparation by Boehringer-Ingelheim, now part of the Roche group; Adapine®, Sinquan® and Sinequan® (Pfizer Inc. ...
Imipramine (tradenames: Janimine®, Tofranil®) is an antidepressant medication belonging to a class called tricyclic antidepressants of the dibenzazepine group, mainly used in the treatment of clinical depression and enuresis. ...
Nortriptyline is a tricyclic antidepressant marketed under the tradenames Aventyl® and Pamelor®. It is used to treat depression. ...
Trimipramine is an tricyclic antidepressant with sedative and anxiolytic properties. ...
Amoxapine (Asendin®; Asendis®; Defanyl®; Demolox®; Moxadil®) is a tricyclic antidepressant of the dibenzoxazepine class. ...
Tetracyclic antidepressants: {Maprotiline} {Mianserin} {Trazodone} {Nefazodone} The structure of the tetracyclic antidepressant mirtazapine A tetracyclic antidepressant is an antidepressant drug from the tetracyclic drug group. ...
To meet Wikipedias quality standards, this article may require cleanup. ...
Mianserin is a tetracyclic antidepressant that has an antihistaminic and hypnosedative, but almost no anticholinergic effect. ...
Trazodone (Desyrel®, Trittico®, Thombran®, Trialodine®) is a psychoactive compound with sedative, anxiolytic, and antidepressant properties. ...
// Introduction Serzone (nefazodone) Serzone ( Nefazodone HCl ) is an antidepressant drug formerly marketed by Bristol-Myers Squibb. ...
Noradrenergic and Specific Serotonergic Antidepressant (NaSSA): {Mirtazapine} Noradrenergic and specific serotonergic antidepressants (abbreviated: NaSSAs) are a relatively new class of antidepressants. ...
Noradrenergic and specific serotonergic antidepressants (abbreviated: NaSSAs) are a relatively new class of antidepressants. ...
Mirtazapine is a prescription antidepressant introduced by Organon International in 1996. ...
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